Anti-DcR3抗体[7G5] (ab57956)
![Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-DcR3 antibody [7G5] (ab57956)](https://www.abcam.cn/ps/products/57/ab57956/Images/ab57956-71682-anti-dcr3-antibody-immunohistochemistry.jpg "Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-DcR3 antibody [7G5] (ab57956)")
Key features and details
- Mouse monoclonal [7G5] to DcR3
- Suitable for: WB, IHC-P
- Reacts with: Human, Recombinant fragment
- Isotype: IgG2a
概述
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产品名称
Anti-DcR3抗体[7G5]
参阅全部 DcR3 一抗 -
描述
小鼠单克隆抗体[7G5] to DcR3 -
宿主
Mouse -
经测试应用
适用于: WB, IHC-Pmore details -
种属反应性
与反应: Human, Recombinant fragment -
免疫原
Recombinant fragment, corresponding to amino acids 32-142 of Human DcR3
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常规说明
This product was changed from ascites to tissue culture supernatant on 12/3/19. Please note that the dilutions may need to be adjusted accordingly. If you have any questions, please do not hesitate to contact our scientific support team.
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles. -
存储溶液
pH: 7.40
Constituent: PBS -
Concentration information loading... -
纯度
Tissue culture supernatant -
克隆
单克隆 -
克隆编号
7G5 -
同种型
IgG2a -
轻链类型
kappa -
研究领域
相关产品
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Compatible Secondaries
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Isotype control
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Recombinant Protein
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab57956于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度；实际最佳的稀释度/浓度应由使用者检定。
| 应用 | Ab评论 | 说明 |
|---|---|---|
| WB |
Use at an assay dependent concentration.
This antibody has only been tested in WB against the recombinant fragment used as immunogen. We have no data on the detection of endogenous protein. |
|
| IHC-P |
Use at an assay dependent concentration.
|
| 说明 |
|---|
|
WB
Use at an assay dependent concentration. This antibody has only been tested in WB against the recombinant fragment used as immunogen. We have no data on the detection of endogenous protein. |
|
IHC-P
Use at an assay dependent concentration. |
靶标
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功能
Decoy receptor for the cytotoxic ligands TNFS14/LIGHT and TNFSF6/FASL. Protects against apoptosis. -
组织特异性
Detected in fetal lung, brain and liver. Detected in adult stomach, spinal cord, lymph node, trachea, spleen, colon and lung. Highly expressed in several primary tumors from colon, stomach, rectum, esophagus and in SW480 colon carcinoma cells. -
序列相似性
Contains 4 TNFR-Cys repeats. -
细胞定位
Secreted. - Information by UniProt
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数据库链接
- Entrez Gene: 8771 Human
- Omim: 603361 Human
- SwissProt: O95407 Human
- Unigene: 434878 Human
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别名
- DcR3 antibody
- Decoy receptor 3 antibody
- Decoy receptor for Fas ligand antibody
see all
图片
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-DcR3 antibody [7G5] (ab57956)
DcR3 antibody (ab57956) used in immunohistochemistry at 3ug/ml on formalin fixed and paraffin embedded human tonsil.
This image was generated using the ascites version of the product.
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![Western blot - Anti-DcR3 antibody [7G5] (ab57956)](https://www.abcam.cn/ps/products/57/ab57956/Images/ab57956-71681-anti-dcr3-antibody-western-blot.jpg)
Western blot - Anti-DcR3 antibody [7G5] (ab57956)Western blot against tagged recombinant protein immunogen using ab57956 DcR3 antibody at 1ug/ml. Predicted band size of immunogen is 38 kDa
This image was generated using the ascites version of the product.
数据表及文件
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Datasheet download
文献 (3)
ab57956 被引用在 3 文献中.
- Wei Y et al. DcR3 promotes proliferation and invasion of pancreatic cancer via a DcR3/STAT1/IRF1 feedback loop. Am J Cancer Res 9:2618-2633 (2019). PubMed: 31911850
- Zhang X et al. Protocadherin ? A3 is expressed in follicular lymphoma irrespective of BCL2 status and is associated with tumor cell growth. Mol Med Rep 14:4622-4628 (2016). IHC-P ; Human . PubMed: 27748813
- Chang WC et al. Expression of decoy receptor 3 in diffuse sclerosing variant of papillary thyroid carcinoma: correlation with M2 macrophage differentiation and lymphatic invasion. Thyroid 23:720-6 (2013). PubMed: 23186064
