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AB169783

Anti-DC-SIGNR 抗体 [EPR11211]

Anti-DC-SIGNR antibody [EPR11211]

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(4 Publications)

Rabbit Recombinant Monoclonal DC-SIGNR antibody. Suitable for IHC-P, WB and reacts with Human samples. Cited in 4 publications.

查看别名

CD299, CD209L, CD209L1, CLEC4M, C-type lectin domain family 4 member M, CD209 antigen-like protein 1, DC-SIGN-related protein, Dendritic cell-specific ICAM-3-grabbing non-integrin 2, Liver/lymph node-specific ICAM-3-grabbing non-integrin, DC-SIGNR, DC-SIGN2, L-SIGN

6 Images
Western blot - Anti-DC-SIGNR antibody [EPR11211] (AB169783)
  • WB

Lab

Western blot - Anti-DC-SIGNR antibody [EPR11211] (AB169783)

All lanes:

Western blot - Anti-DC-SIGNR antibody [EPR11211] (ab169783) at 1/10000 dilution

All lanes:

Human liver lysates at 15 µg

Secondary

All lanes:

Goat Anti-Rabbit IgG (HRP) with minimal cross-reactivity with human IgG at 1/2000 dilution

Predicted band size: 45 kDa

Observed band size: 45 kDa

false

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-DC-SIGNR antibody [EPR11211] (AB169783)
  • IHC-P

Unknown

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-DC-SIGNR antibody [EPR11211] (AB169783)

Immunohistochemical analysis of formalin-fixed, paraffin-embedded Human placenta tissue, labeling DC-SIGNR using unpurified ab169783 at a 1/100 dilution.

Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-DC-SIGNR antibody [EPR11211] (AB169783)
  • IHC-P

Unknown

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-DC-SIGNR antibody [EPR11211] (AB169783)

Immunohistochemical analysis of formalin-fixed, paraffin-embedded Human liver tissue, labeling DC-SIGNR using ab169783 at a 1/100 dilution.

Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-DC-SIGNR antibody [EPR11211] (AB169783)
  • IHC-P

Unknown

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-DC-SIGNR antibody [EPR11211] (AB169783)

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) analysis of human placenta tissue sections labeling DC-SIGNR with purified ab169783 at 1/500 dilution (0.502 μg/ml). Heat mediated antigen retrieval using Bond™ Epitope Retrieval Solution 1 (pH 6.0). Rabbit specific IHC polymer detection kit HRP/DAB (ab209101) was used as the secondary antibody. Negative control : PBS instead of the primary antibody. Hematoxylin was used as a counterstain.

Western blot - Anti-DC-SIGNR antibody [EPR11211] (AB169783)
  • WB

Lab

Western blot - Anti-DC-SIGNR antibody [EPR11211] (AB169783)

All lanes:

Western blot - Anti-DC-SIGNR antibody [EPR11211] (ab169783) at 1/10000 dilution

All lanes:

Human kidney lysates at 15 µg

Secondary

All lanes:

Goat Anti-Rabbit IgG (HRP) with minimal cross-reactivity with human IgG at 1/2000 dilution

Predicted band size: 45 kDa

Observed band size: 45 kDa

false

Western blot - Anti-DC-SIGNR antibody [EPR11211] (AB169783)
  • WB

Lab

Western blot - Anti-DC-SIGNR antibody [EPR11211] (AB169783)

All lanes:

Western blot - Anti-DC-SIGNR antibody [EPR11211] (ab169783) at 1/1000 dilution

All lanes:

Human placenta lysates at 15 µg

Secondary

All lanes:

Goat Anti-Rabbit IgG (HRP) with minimal cross-reactivity with human IgG at 1/2000 dilution

Predicted band size: 45 kDa

Observed band size: 45 kDa

false

不同偶联物与剂型 (1)

  • Carrier free

    Anti-DC-SIGNR antibody [EPR11211] - BSA and Azide free

关键信息

宿主种属

Rabbit

克隆

Monoclonal

克隆号

EPR11211

亚型

IgG

不含载体蛋白

No

反应种属

Human

应用

WB, IHC-P

applications

免疫原

The exact immunogen used to generate this antibody is proprietary information.

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反应性数据

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "IHCP" : {"fullname" : "Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)", "shortname":"IHC-P"}, "IP" : {"fullname" : "Immunoprecipitation", "shortname":"IP"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"}, "ICCIF" : {"fullname" : "Immunocytochemistry/ Immunofluorescence", "shortname":"ICC/IF"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "IHCP-species-checked": "testedAndGuaranteed", "IHCP-species-dilution-info": "1/500", "IHCP-species-notes": "<p><strong>For unpurified use at 1/100 - 1/250</strong></p> Perform heat-mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.", "IP-species-checked": "notRecommended", "IP-species-dilution-info": "", "IP-species-notes": "<p></p>", "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "1/1000 - 1/10000", "WB-species-notes": "<p></p>", "ICCIF-species-checked": "notRecommended", "ICCIF-species-dilution-info": "", "ICCIF-species-notes": "<p></p>" }, "Chimpanzee": { "IHCP-species-checked": "predicted", "IHCP-species-dilution-info": "", "IHCP-species-notes": "", "IP-species-checked": "notRecommended", "IP-species-dilution-info": "", "IP-species-notes": "", "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "", "ICCIF-species-checked": "notRecommended", "ICCIF-species-dilution-info": "", "ICCIF-species-notes": "" }, "Gorilla": { "IHCP-species-checked": "predicted", "IHCP-species-dilution-info": "", "IHCP-species-notes": "", "IP-species-checked": "notRecommended", "IP-species-dilution-info": "", "IP-species-notes": "", "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "", "ICCIF-species-checked": "notRecommended", "ICCIF-species-dilution-info": "", "ICCIF-species-notes": "" } } }
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为什么推荐这个？

我们推荐这个产品，因为它经常被用于相同的实验或相关的研究。

我们建议您务必查阅产品说明书，以确认其是否符合您的实验需求；若有疑问，也可联系我们的技术团队获取协助。

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产品详情

Species reactivity
Mouse, Rat: We have preliminary internal testing data to indicate this antibody may not react with these species.
Please contact us for more information.

Patented technology
Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb® patents.

What are the advantages of a recombinant monoclonal antibody?
This product is a recombinant monoclonal antibody, which offers several advantages including:

  • - High batch-to-batch consistency and reproducibility
  • - Improved sensitivity and specificity
  • - Long-term security of supply
  • - Animal-free batch production

For more information, read more on recombinant antibodies.

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性能和储存信息

形式
Liquid
纯化工艺
Affinity purification Protein A
存储溶液
Preservative: 0.01% Sodium azide Constituents: PBS, 40% Glycerol (glycerin, glycerine), 0.05% BSA
运输条件
Blue Ice
推荐的短期储存时间
1-2 weeks
推荐的短期储存条件
+4°C
推荐的长期储存条件
-20°C
分装信息
Upon delivery aliquot
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产品实验方案

For this product, it's our understanding that no specific protocols are required. You can visit:
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靶点信息

Probable pathogen-recognition receptor involved in peripheral immune surveillance in liver. May mediate the endocytosis of pathogens which are subsequently degraded in lysosomal compartments. Is a receptor for ICAM3, probably by binding to mannose-like carbohydrates.. (Microbial infection) Acts as an attachment receptor for Ebolavirus.. (Microbial infection) Acts as an attachment receptor for Hepatitis C virus.. (Microbial infection) Acts as an attachment receptor for HIV-1.. (Microbial infection) Acts as an attachment receptor for Human coronavirus 229E.. (Microbial infection) Acts as an attachment receptor for Human cytomegalovirus/HHV-5.. (Microbial infection) Acts as an attachment receptor for Influenzavirus.. (Microbial infection) Acts as an attachment receptor for SARS-CoV.. (Microbial infection) Acts as an attachment receptor for West-nile virus.. (Microbial infection) Acts as an attachment receptor for Japanese encephalitis virus.. (Microbial infection) Acts as an attachment receptor for Marburg virus glycoprotein.. (Microbial infection) Recognition of M.bovis by dendritic cells may occur partially via this molecule.
See full target information CLEC4M
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文献 (4)

Recent publications for all applications. Explore the full list and refine your search

International journal of general medicine 16:1317-1332 PubMed37089135

2023

Investigation of Diagnostic and Prognostic Value of CLEC4M of Non-Small Cell Lung Carcinoma Associated with Immune Microenvironment.

Applications

Unspecified application

Species

Unspecified reactive species

Huan Liu,Zhiping Yu,Yueguang Liu,Mingzhen Li,Cheng Chen,Zhiyu Zhu,Fang Liu,Liming Tan

Oncology letters 19:1711-1720 PubMed32194663

2020

High expression levels of CLEC4M indicate poor prognosis in patients with hepatocellular carcinoma.

Applications

Unspecified application

Species

Unspecified reactive species

Liuping Luo,Lihong Chen,Kun Ke,Bixing Zhao,Lili Wang,Cuilin Zhang,Fei Wang,Naishun Liao,Xiaoyuan Zheng,Xiaolong Liu,Yingchao Wang,Jingfeng Liu

Oncology letters 19:69-76 PubMed31897116

2020

Decreased DC-SIGNR expression in hepatocellular carcinoma predicts poor patient prognosis.

Applications

Unspecified application

Species

Unspecified reactive species

Hai-Bing Xia,Hui-Ju Wang,Shu-Shu Song,Jun-Gang Zhang,Xiang-Lei He,Zhi-Ming Hu,Cheng-Wu Zhang,Dong-Sheng Huang,Xiao-Zhou Mou

Oncology letters 14:2813-2821 PubMed28927040

2017

Overexpression of dendritic cell-specific intercellular adhesion molecule-3-grabbing nonintegrin-related protein in cervical cancer and correlation with squamous cell carcinoma antigen.

Applications

Unspecified application

Species

Unspecified reactive species

Xiangdong Wang,Yangmei Jiang,Menglang Yuan,Chunlin Chen,Keyong Wang,Qianshi Zhang,Yunfei Zuo,Shuangyi Ren
View all publications
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