重组Anti-DBC1抗体[EPR7311] (ab128890)
Key features and details
- Produced recombinantly (animal-free) for high batch-to-batch consistency and long term security of supply
- Rabbit monoclonal [EPR7311] to DBC1
- Suitable for: Flow Cyt (Intra), WB
- Reacts with: Human
Related conjugates and formulations
概述
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产品名称
Anti-DBC1抗体[EPR7311]
参阅全部 DBC1 一抗 -
描述
兔单克隆抗体[EPR7311] to DBC1 -
宿主
Rabbit -
经测试应用
适用于: Flow Cyt (Intra), WBmore details
不适用于: ICC/IF,IHC-P or IP -
种属反应性
与反应: Human
预测可用于: Mouse, Rat -
免疫原
Synthetic peptide within Human DBC1 aa 1-100. The exact sequence is proprietary.
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阳性对照
- Human fetal heart and MCF7 cell lysates; MCF7 cells.
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常规说明
This product is a recombinant monoclonal antibody, which offers several advantages including:
- - High batch-to-batch consistency and reproducibility
- - Improved sensitivity and specificity
- - Long-term security of supply
- - Animal-free production
Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb® patents.
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Store at -20°C. Stable for 12 months at -20°C. -
解离常数(KD)
KD = 1.39 x 10 -10 M Learn more about KD -
存储溶液
pH: 7.20
Preservative: 0.01% Sodium azide
Constituents: 9% PBS, 40% Glycerol (glycerin, glycerine), 0.05% BSA, 50% Tissue culture supernatant -
Concentration information loading...
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纯度
Tissue culture supernatant -
克隆
单克隆 -
克隆编号
EPR7311 -
同种型
IgG -
研究领域
相关产品
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Alternative Versions
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Isotype control
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab128890于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度;实际最佳的稀释度/浓度应由使用者检定。
应用 | Ab评论 | 说明 |
---|---|---|
Flow Cyt (Intra) |
1/10 - 1/100.
ab172730 - Rabbit monoclonal IgG, is suitable for use as an isotype control with this antibody. |
|
WB |
1/10000 - 1/50000. Detects a band of approximately 88 kDa (predicted molecular weight: 89 kDa).
|
说明 |
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Flow Cyt (Intra)
1/10 - 1/100. ab172730 - Rabbit monoclonal IgG, is suitable for use as an isotype control with this antibody. |
WB
1/10000 - 1/50000. Detects a band of approximately 88 kDa (predicted molecular weight: 89 kDa). |
靶标
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功能
Inhibits cell proliferation by negative regulation of the G1/S transition. Mediates cell death which is not of the classical apoptotic type and regulates expression of components of the plasminogen pathway. -
组织特异性
Highly expressed in brain. Weakly expressed in heart, lung, skeletal muscle, kidney, thymus, prostate, testis and small intestine. -
序列相似性
Belongs to the FAM5 family.
Contains 1 MACPF domain. -
细胞定位
Cytoplasm. - Information by UniProt
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数据库链接
- Entrez Gene: 1620 Human
- Entrez Gene: 56710 Mouse
- Entrez Gene: 140610 Rat
- Omim: 602865 Human
- SwissProt: O60477 Human
- SwissProt: Q920P3 Mouse
- SwissProt: Q925T8 Rat
- Unigene: 532316 Human
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别名
- BMP/retinoic acid-inducible neural-specific protein 1 antibody
- BRINP1 antibody
- DBC1 antibody
see all
图片
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All lanes : Anti-DBC1 antibody [EPR7311] (ab128890) at 1/10000 dilution
Lane 1 : Human fetal heart tissue lysate
Lane 2 : MCF7 cell lysate
Lysates/proteins at 10 µg per lane.
Secondary
All lanes : HRP labelled goat anti-rabbit IgG at 1/2000 dilution
Predicted band size: 89 kDa -
ab128890 at 1/10 dilution staining DBC1 in permeabilized MCF7 cells by intracellular flow cytometry (red). Rabbit IgG negative control (green).
数据表及文件
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SDS download
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Datasheet download
文献 (1)
ab128890 被引用在 1 文献中.
- Li L et al. NANOGP8 expression regulates gastric cancer cell progression by transactivating DBC1 in gastric cancer MKN-45 cells. Oncol Lett 17:555-563 (2019). PubMed: 30655801