Anti-Dab1 (phospho Y232)抗体(ab78200)
Key features and details
- Rabbit polyclonal to Dab1 (phospho Y232)
- Suitable for: WB
- Reacts with: Human
- Isotype: IgG
概述
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产品名称
Anti-Dab1 (phospho Y232)抗体
参阅全部 Dab1 一抗 -
描述
兔多克隆抗体to Dab1 (phospho Y232) -
宿主
Rabbit -
经测试应用
适用于: WBmore details -
种属反应性
与反应: Human
预测可用于: Mouse, Rat
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免疫原
Synthetic peptide corresponding to Human Dab1 (phospho Y232).
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阳性对照
- Extracts from LOVO cells.
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常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles. -
存储溶液
pH: 7
Preservative: 0.02% Sodium azide
Constituents: 50% Glycerol, 0.87% Sodium chloride, PBS -
Concentration information loading... -
纯度
Immunogen affinity purified -
纯化说明
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatography using non-phosphopeptide corresponding to the phosphorylation site. -
克隆
多克隆 -
同种型
IgG -
研究领域
相关产品
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Compatible Secondaries
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Isotype control
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab78200于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度；实际最佳的稀释度/浓度应由使用者检定。
| 应用 | Ab评论 | 说明 |
|---|---|---|
| WB |
1/500 - 1/1000. Detects a band of approximately 67 kDa (predicted molecular weight: 67 kDa).
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| 说明 |
|---|
|
WB
1/500 - 1/1000. Detects a band of approximately 67 kDa (predicted molecular weight: 67 kDa). |
靶标
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功能
Adapter molecule functioning in neural development. May regulate SIAH1 activity. -
序列相似性
Contains 1 PID domain. -
结构域
The PID domain specifically binds to the Asn-Pro-Xaa-Tyr(P) motif found in many tyrosine-phosphorylated proteins. -
翻译后修饰
Phosphorylated on Tyr-198 and Tyr-220 upon reelin induction in embryonic neurons (By similarity). Also phosphorylated on Ser-524 independently of reelin signaling. - Information by UniProt
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数据库链接
- Entrez Gene: 1600 Human
- Entrez Gene: 13131 Mouse
- Entrez Gene: 266729 Rat
- Omim: 603448 Human
- SwissProt: O75553 Human
- SwissProt: P97318 Mouse
- SwissProt: Q8CJH2 Rat
- Unigene: 477370 Human
see all -
别名
- Dab 1 antibody
- Dab reelin signal transducer 1 antibody
- Dab, reelin signal transducer, homolog 1 (Drosophila) antibody
see all
图片
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Western blot - Anti-Dab1 (phospho Y232) antibody (ab78200)All lanes : Anti-Dab1 (phospho Y232) antibody (ab78200) at 1/500 dilution
Lane 1 : Extracts from LOVO cells
Lane 2 : Extracts from LOVO cells plus 5µg immunizing peptide
Lysates/proteins at 5 µg per lane.
Predicted band size: 67 kDa
Observed band size: 67 kDa
数据表及文件
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SDS download
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Datasheet download
文献 (2)
ab78200 被引用在 2 文献中.
- Racetin A et al. Expression and localization of DAB1 and Reelin during normal human kidney development. Croat Med J 60:521-531 (2019). PubMed: 31894918
- Rogers JT et al. Reelin supplementation enhances cognitive ability, synaptic plasticity, and dendritic spine density. Learn Mem 18:558-64 (2011). PubMed: 21852430