Anti-Cytomegalovirus pp65抗体[3A12] - BSA and Azide free (ab6503)
Key features and details
- Mouse monoclonal [3A12] to Cytomegalovirus pp65 - BSA and Azide free
- Suitable for: WB, ICC/IF
- Reacts with: Human cytomegalovirus
- Isotype: IgG2a
概述
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产品名称
Anti-Cytomegalovirus pp65抗体[3A12] - BSA and Azide free
参阅全部 Cytomegalovirus pp65 一抗 -
描述
小鼠单克隆抗体[3A12] to Cytomegalovirus pp65 - BSA and Azide free -
宿主
Mouse -
特异性
Cytomegalovirus pp65 (Lower Matrix Protein). -
经测试应用
适用于: WB, ICC/IFmore details -
种属反应性
与反应: Human cytomegalovirus -
免疫原
Tissue, cells or virus corresponding to Cytomegalovirus pp65.
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常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles. -
存储溶液
pH: 7.40
Constituent: 100% PBS -
无载体
是 -
Concentration information loading... -
纯度
Protein A purified -
克隆
单克隆 -
克隆编号
3A12 -
骨髓瘤
NS1/1-Ag4-1 -
同种型
IgG2a -
轻链类型
kappa -
研究领域
相关产品
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Compatible Secondaries
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Isotype control
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Recombinant Protein
应用
| 应用 | Ab评论 | 说明 |
|---|---|---|
| WB |
1/16000.
|
|
| ICC/IF |
1/3200.
|
| 说明 |
|---|
|
WB
1/16000. |
|
ICC/IF
1/3200. |
靶标
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相关性
Cytomegalovirus is a member of the herpes virus group, which includes herpes simplex virus types 1 and 2, varicella zoster virus (which causes chicken pox), and Epstein Barr virus (which causes infectious mononucleosis). These viruses share a characteristic ability to remain dormant within the body over a long period. CMV viral genes are co-ordinately expressed in groups at various times after infection. Early viral proteins are expressed in the nucleus of infected cells within 3 to 24 hours of infection prior to the commencement of viral DNA replication. This is followed by expression of the early intermediate genes, which encode enzymes required for viral DNA replication. After 48 to 72 hours, a number of late viral antigens may be demonstrated in the nuclei and cytoplasm of infected cells. pp65 is a 65kD phosphorylated glycoprotein and is the most abundant of the late antigens. -
数据库链接
- Entrez Gene: 1487754 Human cytomegalovirus
- SwissProt: P06725 Human cytomegalovirus
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别名
- 65 kDa matrix phosphoprotein antibody
- 65 kDa phosphoprotein antibody
- Tegument protein pp65 antibody
- Tegument protein UL83 antibody
实验方案
数据表及文件
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SDS download
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Datasheet download
文献 (26)
ab6503 被引用在 26 文献中.
- Vezzani G et al. The Human Cytomegalovirus UL116 Glycoprotein Is a Chaperone to Control gH-Based Complexes Levels on Virions. Front Microbiol 12:630121 (2021). PubMed: 33889136
- Gonzalez-Perez AC et al. The Zinc Finger Antiviral Protein ZAP Restricts Human Cytomegalovirus and Selectively Binds and Destabilizes Viral UL4/UL5 Transcripts. mBio 12:N/A (2021). PubMed: 33947766
- Liu M et al. Ferulic acid inhibits LPS-induced apoptosis in bovine mammary epithelial cells by regulating the NF-κB and Nrf2 signalling pathways to restore mitochondrial dynamics and ROS generation. Vet Res 52:104 (2021). PubMed: 34256834
- Le-Trilling VTK et al. The Human Cytomegalovirus pUL145 Isoforms Act as Viral DDB1-Cullin-Associated Factors to Instruct Host Protein Degradation to Impede Innate Immunity. Cell Rep 30:2248-2260.e5 (2020). PubMed: 32075763
- Weathers SP et al. Glioblastoma-mediated Immune Dysfunction Limits CMV-specific T Cells and Therapeutic Responses: Results from a Phase I/II Trial. Clin Cancer Res 26:3565-3577 (2020). PubMed: 32299815