Anti-Cytomegalovirus IE1 and IE2抗体[CH160] - BSA and Azide free (ab53495)
Key features and details
- Mouse monoclonal [CH160] to Cytomegalovirus IE1 and IE2 - BSA and Azide free
- Suitable for: WB, ICC/IF
- Reacts with: Human cytomegalovirus
- Isotype: IgG1
概述
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产品名称
Anti-Cytomegalovirus IE1 and IE2抗体[CH160] - BSA and Azide free -
描述
小鼠单克隆抗体[CH160] to Cytomegalovirus IE1 and IE2 - BSA and Azide free -
宿主
Mouse -
特异性
ab53495 reacts with cytomegalovirus IE1 and IE2. -
经测试应用
适用于: WB, ICC/IFmore details -
种属反应性
与反应: Human cytomegalovirus -
免疫原
Tissue, cells or virus corresponding to Cytomegalovirus IE1 and IE2. HCMV AD169 IC Extract.
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常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles. -
存储溶液
pH: 7.40
Constituent: PBS -
无载体
是 -
Concentration information loading... -
纯度
Protein G purified -
克隆
单克隆 -
克隆编号
CH160 -
同种型
IgG1 -
研究领域
相关产品
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Compatible Secondaries
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Isotype control
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab53495于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度；实际最佳的稀释度/浓度应由使用者检定。
| 应用 | Ab评论 | 说明 |
|---|---|---|
| WB |
Use a concentration of 10 µg/ml.
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| ICC/IF |
Use a concentration of 10 µg/ml.
|
| 说明 |
|---|
|
WB
Use a concentration of 10 µg/ml. |
|
ICC/IF
Use a concentration of 10 µg/ml. |
靶标
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相关性
The IE1/2 transcriptional control region of human cytomegalovirus drives the expression of the HCMV major immediate-early genes (UL123-122), which encode proteins necessary for initiation of the virus replicative cycle. Nucleotide sequence polymorphism in this region of the viral genome could account for variations in the replication of human cytomegalovirus strains. -
数据库链接
- Entrez Gene: 1487821 Human cytomegalovirus
- Entrez Gene: 1487822 Human cytomegalovirus
- SwissProt: P13202 Human cytomegalovirus
- SwissProt: P19893 Human cytomegalovirus
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别名
- 45 kDa immediate-early protein 2 antibody
- 55 kDa immediate-early protein 2 antibody
- HCMV antibody
see all
实验方案
数据表及文件
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Datasheet download
文献 (21)
ab53495 被引用在 21 文献中.
- Li J et al. Analysis of the mRNA export protein ZC3H11A in HCMV infection and pan-cancer. Front Microbiol 14:1296725 (2023). PubMed: 38033582
- Schwartz M et al. Molecular characterization of human cytomegalovirus infection with single-cell transcriptomics. Nat Microbiol 8:455-468 (2023). PubMed: 36732471
- Ma G et al. HCMV-IE2 promotes atherosclerosis by inhibiting vascular smooth muscle cells' pyroptosis. Front Microbiol 14:1177391 (2023). PubMed: 37234524
- Niu D et al. Human Cytomegalovirus IE2 Disrupts Neural Progenitor Development and Induces Microcephaly in Transgenic Mouse. Mol Neurobiol 60:3883-3897 (2023). PubMed: 36991278
- Zhang X et al. Human Cytomegalovirus-IE2 Affects Embryonic Liver Development and Survival in Transgenic Mouse. Cell Mol Gastroenterol Hepatol 14:494-511 (2022). PubMed: 35569816
