AB54023

Anti-Cytomegalovirus Glycoprotein B抗体[HCMV37]

Name: Cytomegalovirus Glycoprotein B抗体[HCMV37] (ab54023)| Abcam中文官网
Brand: Abcam Limited
SKU: AB54023
Price: 4922 CNY
Availability: InStock

Anti-Cytomegalovirus Glycoprotein B antibody [HCMV37]

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(6 Publications)

Mouse Monoclonal GB antibody. Suitable for ICC/IF, FuncS (Neut/Block), IHC-Fr, ELISA and reacts with Human cytomegalovirus samples. Cited in 6 publications.

查看别名

UL55, gB, Envelope glycoprotein B

1 Images

Immunocytochemistry/ Immunofluorescence - Anti-Cytomegalovirus Glycoprotein B antibody [HCMV37] (AB54023)

ICC/IF

PubMed

Immunocytochemistry/ Immunofluorescence - Anti-Cytomegalovirus Glycoprotein B antibody [HCMV37] (AB54023)

ab54023, staining Cytomegalovirus Glycoprotein B in monocyte-derived dendritic cells infected with Human cytomegalovirus (VHL/E strain), cultured for 3 hours (left panels) and 24 hours (right panels), by Immunocytochemistry/ Immunofluorescence.

Cells were fixed with paraformaldehyde and permeabilized with 0.2% Triton X-100 in PBS for 10 minutes at room temperature. Samples were incubated with primary antibody and an AlexaFluor®568-conjugated goat anti-mouse monoclonal IgG was used as the secondary antibody.

Image from Haspot F et al., PLoS One. 2012;7(4):e34795. Epub 2012 Apr 9. Fig 2.; doi:10.1371/journal.pone.0034795; April 9, 2012, PLoS ONE 7(4): e34795.

不同偶联物与剂型 (1)

519 FITC

FITC Anti-Cytomegalovirus Glycoprotein B antibody [HCMV37]

关键信息

宿主种属

Mouse

克隆

Monoclonal

克隆号

HCMV37

亚型

IgG2a

不含载体蛋白

反应种属

Human cytomegalovirus

应用

FuncS (Neut/Block), IHC-Fr, ICC/IF, ELISA

applications

特异性

This antibody is specific for Cytomegalovirus glycoprotein B late neutralizing antigen. Reacts with MRC-5 infected cells but not uninfected cells.

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反应性数据

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "ICCIF" : {"fullname" : "Immunocytochemistry/ Immunofluorescence", "shortname":"ICC/IF"}, "FuncSNeutBlock" : {"fullname" : "Functional Studies (Neut/Block)", "shortname":"FuncS (Neut/Block)"}, "IHCFr" : {"fullname" : "Immunohistochemistry (Frozen sections)", "shortname":"IHC-Fr"}, "ELISA" : {"fullname" : "ELISA", "shortname":"ELISA"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human cytomegalovirus": { "ICCIF-species-checked": "guaranteed", "ICCIF-species-dilution-info": "", "ICCIF-species-notes": "", "FuncSNeutBlock-species-checked": "guaranteed", "FuncSNeutBlock-species-dilution-info": "", "FuncSNeutBlock-species-notes": "", "IHCFr-species-checked": "guaranteed", "IHCFr-species-dilution-info": "", "IHCFr-species-notes": "", "ELISA-species-checked": "guaranteed", "ELISA-species-dilution-info": "", "ELISA-species-notes": "" } } }

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性能和储存信息

形式

Liquid

纯化工艺

Affinity purification Protein A

存储溶液

Preservative: 0.09% Sodium azide Constituents: PBS

运输条件

Blue Ice

分装信息

Upon delivery aliquot

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产品实验方案

For this product, it's our understanding that no specific protocols are required. You can visit:

Visit the General protocols
Visit the Troubleshooting

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靶点信息

Envelope glycoprotein that plays a role in host cell entry, cell to-cell virus transmission, and fusion of infected cells. May be involved in the initial attachment via binding to heparan sulfate together with the gM/gN complex that binds heparin with higher affinity. Interacts with host integrin ITGB1, PDGFRA and EGFR that likely serve as postattachment entry receptors. Also participates in the fusion of viral and cellular membranes leading to virus entry into the host cell. Membrane fusion is mediated by the fusion machinery composed at least of gB and the heterodimer gH/gL.

See full target information gB

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文献 (6)

Recent publications for all applications. Explore the full list and refine your search

ACS sensors 5:147-153 PubMed31850749

2020

Nanoparticle Reservoirs for Paper-Only Immunosensors.

Applications

Unspecified application

Species

Unspecified reactive species

Alejandra Alba-Patiño,Cristina Adrover-Jaume,Roberto de la Rica

Oncotarget 8:25989-25999 PubMed27517625

2016

CMV70-3P miRNA contributes to the CMV mediated glioma stemness and represents a target for glioma experimental therapy.

Applications

Unspecified application

Species

Unspecified reactive species

Ilya V Ulasov,Natalya V Kaverina,Dhimankrishna Ghosh,Marya A Baryshnikova,Zaira G Kadagidze,Apollon I Karseladze,Anatoly Y Baryshnikov,Charles S Cobbs

Placenta 36:667-73 PubMed25814471

2015

Viperin is induced following toll-like receptor 3 (TLR3) ligation and has a virus-responsive function in human trophoblast cells.

Applications

Unspecified application

Species

Unspecified reactive species

B Wang,Y Fang,Y Wu,K Koga,Y Osuga,S Lv,D Chen,Y Zhu,J Wang,H Huang

Clinical and vaccine immunology : CVI 21:174-80 PubMed24334684

2013

Enveloped virus-like particle expression of human cytomegalovirus glycoprotein B antigen induces antibodies with potent and broad neutralizing activity.

Applications

Neut

Species

Unspecified reactive species

Marc Kirchmeier,Anne-Catherine Fluckiger,Catalina Soare,Jasminka Bozic,Barthelemy Ontsouka,Tanvir Ahmed,Abebaw Diress,Lenore Pereira,Florian Schödel,Stanley Plotkin,Charlotte Dalba,David Klatzmann,David E Anderson

PloS one 7:e34795 PubMed22496863

2012

Human cytomegalovirus entry into dendritic cells occurs via a macropinocytosis-like pathway in a pH-independent and cholesterol-dependent manner.

Applications

ICC/IF

Species

Unspecified reactive species

Fabienne Haspot,Amélie Lavault,Christian Sinzger,Kerstin Laib Sampaio,York-Dieter Stierhof,Paul Pilet,Céline Bressolette-Bodin,Franck Halary

The EMBO journal 5:3057-63 PubMed3024973

1986

Identification of the human cytomegalovirus glycoprotein B gene and induction of neutralizing antibodies via its expression in recombinant vaccinia virus.

Applications

Unspecified application

Species

Unspecified reactive species

M P Cranage,T Kouzarides,A T Bankier,S Satchwell,K Weston,P Tomlinson,B Barrell,H Hart,S E Bell,A C Minson

View all publications

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Anti-Cytomegalovirus Glycoprotein B抗体[HCMV37]