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AB238013

Anti-Cytokeratin 6a抗体[KRT6A/2368]

Anti-Cytokeratin 6a antibody [KRT6A/2368]

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(3 Publications)

Mouse Monoclonal K2C6A antibody. Suitable for IHC-P, Protein Array and reacts with Human samples. Cited in 3 publications. Immunogen corresponding to Recombinant Full Length Protein corresponding to Human KRT6A.

查看别名

K6A, KRT6D, KRT6A, Cytokeratin-6A, Cytokeratin-6D, Keratin-6A, Type-II keratin Kb6, CK-6A, CK-6D

4 Images
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Cytokeratin 6a antibody [KRT6A/2368] (AB238013)
  • IHC-P

Supplier Data

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Cytokeratin 6a antibody [KRT6A/2368] (AB238013)

Formalin-fixed, paraffin-embedded human prostate carcinoma tissue stained for Cytokeratin 6 using ab238013 at 2 μg/ml in immunohistochemical analysis.

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Cytokeratin 6a antibody [KRT6A/2368] (AB238013)
  • IHC-P

Supplier Data

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Cytokeratin 6a antibody [KRT6A/2368] (AB238013)

Formalin-fixed, paraffin-embedded human basal cell carcinoma tissue stained for Cytokeratin 6 using ab238013 at 2 μg/ml in immunohistochemical analysis.

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Cytokeratin 6a antibody [KRT6A/2368] (AB238013)
  • IHC-P

Supplier Data

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Cytokeratin 6a antibody [KRT6A/2368] (AB238013)

Formalin-fixed, paraffin-embedded human basal cell tissue stained for Cytokeratin 6 using ab238013 at 2 μg/ml in immunohistochemical analysis.

Protein Array - Anti-Cytokeratin 6a antibody [KRT6A/2368] (AB238013)
  • Protein Array

Unknown

Protein Array - Anti-Cytokeratin 6a antibody [KRT6A/2368] (AB238013)

ab238013 was tested in protein array against over 19000 different full-length human proteins.
Z- and S- Score : The Z-score represents the strength of a signal that a monoclonal antibody (MAb) (in combination with a fluorescently-tagged anti-IgG secondary antibody) produces when binding to a particular protein on the HuProtTM array. Z-scores are described in units of standard deviations (SD's) above the mean value of all signals generated on that array. If targets on HuProtTM are arranged in descending order of the Z-score, the S-score is the difference (also in units of SD's) between the Z-score. S-score therefore represents the relative target specificity of a MAb to its intended target.
A MAb is specific to its intended target if the MAb has an S-score of at least 2.5. For example, if a MAb binds to protein X with a Z-score of 43 and to protein Y with a Z-score of 14, then the S-score for the binding of that MAb to protein X is equal to 29.

关键信息

宿主种属

Mouse

克隆

Monoclonal

克隆号

KRT6A/2368

亚型

IgG2a

轻链类型

kappa

不含载体蛋白

No

反应种属

Human

应用

IHC-P, Protein Array

applications

免疫原

Recombinant Full Length Protein corresponding to Human KRT6A.

P02538

反应性数据

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "IHCP" : {"fullname" : "Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)", "shortname":"IHC-P"}, "ProteinArray" : {"fullname" : "Protein Array", "shortname":"Protein Array"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "IHCP-species-checked": "testedAndGuaranteed", "IHCP-species-dilution-info": "1-2 µg/mL", "IHCP-species-notes": "<p>Incubate with primary antibody for 30 minutes at RT.</p> Perform heat-mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.", "ProteinArray-species-checked": "testedAndGuaranteed", "ProteinArray-species-dilution-info": "", "ProteinArray-species-notes": "<p></p>" } } }

性能和储存信息

形式
Liquid
纯化工艺
Affinity purification Protein A/G
纯化说明
Purified from Bioreactor Concentrate by Protein A/G.
存储溶液
pH: 7.2 - 7.4 Preservative: 0.05% Sodium azide Constituents: PBS, 0.05% BSA
运输条件
Blue Ice
推荐的短期储存时间
1-2 weeks
推荐的短期储存条件
+4°C
推荐的长期储存条件
-20°C
分装信息
Upon delivery aliquot
储存信息
Avoid freeze / thaw cycle

产品实验方案

For this product, it's our understanding that no specific protocols are required. You can visit:

靶点信息

Epidermis-specific type I keratin involved in wound healing. Involved in the activation of follicular keratinocytes after wounding, while it does not play a major role in keratinocyte proliferation or migration. Participates in the regulation of epithelial migration by inhibiting the activity of SRC during wound repair.
See full target information KRT6A

文献 (3)

Recent publications for all applications. Explore the full list and refine your search

The Journal of investigative dermatology 143:2052-2064.e5 PubMed37044260

2023

Bacterial Pyocyanin Inducible Keratin 6A Accelerates Closure of Epithelial Defect under Conditions of Mitochondrial Dysfunction.

Applications

Unspecified application

Species

Unspecified reactive species

Subhadip Ghatak,Craig Hemann,James Boslett,Kanhaiya Singh,Anu Sharma,Mohamed S El Masry,Ahmed Safwat Abouhashem,Nandini Ghosh,Shomita S Mathew-Steiner,Sashwati Roy,Jay L Zweier,Chandan K Sen

Cell cycle (Georgetown, Tex.) 21:1479-1490 PubMed35311447

2022

expedites bladder cancer progression, regulated by miR-31-5p.

Applications

Unspecified application

Species

Unspecified reactive species

Yuan Chen,Shiben Ji,Jianxin Ying,Yongchang Sun,Jun Liu,Guohong Yin

Hepatology (Baltimore, Md.) 74:847-863 PubMed33554350

2021

The Clinical Significance of Hepatic CD69 CD103 CD8 Resident-Memory T Cells in Autoimmune Hepatitis.

Applications

Unspecified application

Species

Unspecified reactive species

Zhengrui You,You Li,Qixia Wang,Zhibin Zhao,Yikang Li,Qiwei Qian,Bo Li,Jun Zhang,Bingyuan Huang,Jubo Liang,Ruiling Chen,Zhuwan Lyu,Yong Chen,Min Lian,Xiao Xiao,Qi Miao,Jingyuan Fang,Zhexiong Lian,M Eric Gershwin,Ruqi Tang,Xiong Ma
View all publications

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