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AB20203

Anti-Cytokeratin 5 + 14抗体[LH8]

Anti-Cytokeratin 5 + 14 antibody [LH8]

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(2 Publications)

Mouse Monoclonal Cytokeratin 14 antibody. Suitable for IHC-P, IHC-Fr and reacts with Human samples. Cited in 2 publications. Immunogen corresponding to Synthetic Peptide within Human KRT5.

查看别名

Cytokeratin-14, Keratin-14, CK-14, K14, KRT14, 58 kDa cytokeratin, Cytokeratin-5, Keratin-5, Type-II keratin Kb5, CK-5, K5, KRT5, CK5

关键信息

宿主种属

Mouse

克隆

Monoclonal

克隆号

LH8

亚型

IgM

轻链类型

unknown

不含载体蛋白

No

反应种属

Human

应用

IHC-P, IHC-Fr

applications

免疫原

Synthetic Peptide within Human KRT5. The exact immunogen used to generate this antibody is proprietary information.

P13647

特异性

Detected in the basal layer, lowered within the more apically located layers specifically in the stratum spinosum, stratum granulosum but is not detected in stratum corneum. Strongly expressed in the outer root sheath of anagen follicles but not in the germinative matrix, inner root sheath or hair. Found in keratinocytes surrounding the club hair during telogen.

反应性数据

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "IHCP" : {"fullname" : "Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)", "shortname":"IHC-P"}, "IHCFr" : {"fullname" : "Immunohistochemistry (Frozen sections)", "shortname":"IHC-Fr"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "IHCP-species-checked": "guaranteed", "IHCP-species-dilution-info": "", "IHCP-species-notes": "<p></p>", "IHCFr-species-checked": "guaranteed", "IHCFr-species-dilution-info": "", "IHCFr-species-notes": "<p></p>" } } }

性能和储存信息

形式
Liquid
纯化工艺
Affinity purification Protein A/G
存储溶液
Preservative: 0.02% Sodium azide Constituents: PBS
运输条件
Blue Ice
推荐的短期储存时间
1-2 weeks
推荐的短期储存条件
+4°C
推荐的长期储存条件
-20°C
分装信息
Upon delivery aliquot
储存信息
Avoid freeze / thaw cycle

产品实验方案

For this product, it's our understanding that no specific protocols are required. You can visit:

靶点信息

The nonhelical tail domain is involved in promoting KRT5-KRT14 filaments to self-organize into large bundles and enhances the mechanical properties involved in resilience of keratin intermediate filaments in vitro.
See full target information Keratin, type I cytoskeletal 14

其他靶点

Keratin, type II cytoskeletal 5

文献 (2)

Recent publications for all applications. Explore the full list and refine your search

PloS one 9:e94118 PubMed24705787

2014

Expression of RAGE and HMGB1 in thymic epithelial tumors, thymic hyperplasia and regular thymic morphology.

Applications

IHC-P

Species

Human

Bernhard Moser,Stefan Janik,Ana-Iris Schiefer,Leonhard Müllauer,Christine Bekos,Anke Scharrer,Michael Mildner,Ferenc Rényi-Vámos,Walter Klepetko,Hendrik Jan Ankersmit

Proceedings of the National Academy of Sciences of the United States of America 104:973-8 PubMed17210912

2007

Identification of a subpopulation of cells with cancer stem cell properties in head and neck squamous cell carcinoma.

Applications

IHC-Fr

Species

Human

M E Prince,R Sivanandan,A Kaczorowski,G T Wolf,M J Kaplan,P Dalerba,I L Weissman,M F Clarke,L E Ailles
View all publications

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