Anti-Cystatin SN/CST1抗体(ab124281)
Key features and details
- Rabbit polyclonal to Cystatin SN/CST1
- Suitable for: IHC-P, ICC/IF, ELISA
- Reacts with: Human
- Isotype: IgG
概述
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产品名称
Anti-Cystatin SN/CST1抗体
参阅全部 Cystatin SN/CST1 一抗 -
描述
兔多克隆抗体to Cystatin SN/CST1 -
宿主
Rabbit -
经测试应用
适用于: IHC-P, ICC/IF, ELISAmore details -
种属反应性
与反应: Human -
免疫原
Synthetic peptide corresponding to Human Cystatin SN/CST1 (internal sequence).
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阳性对照
- Human prostate tissue. MCF7 cells.
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常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles. -
存储溶液
pH: 7.40
Preservative: 0.02% Sodium azide
Constituents: 50% Glycerol (glycerin, glycerine), 0.88% Sodium chloride, 49% PBS -
Concentration information loading... -
纯度
Immunogen affinity purified -
克隆
多克隆 -
同种型
IgG -
研究领域
相关产品
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Compatible Secondaries
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Isotype control
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Recombinant Protein
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab124281于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度；实际最佳的稀释度/浓度应由使用者检定。
| 应用 | Ab评论 | 说明 |
|---|---|---|
| IHC-P |
Use a concentration of 5 µg/ml.
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| ICC/IF |
1/100 - 1/500.
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| ELISA |
Use at an assay dependent concentration.
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| 说明 |
|---|
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IHC-P
Use a concentration of 5 µg/ml. |
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ICC/IF
1/100 - 1/500. |
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ELISA
Use at an assay dependent concentration. |
靶标
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功能
Human saliva appears to contain several cysteine proteinase inhibitors that are immunologically related to cystatin S but that differ in their specificity due to amino acid sequence differences. Cystatin SN, with a pI of 7.5, is a much better inhibitor of papain and dipeptidyl peptidase I than is cystatin S, although both inhibit ficin equally well. -
组织特异性
Expressed in submandibular and sublingual saliva but not in parotid saliva (at protein level). Expressed in saliva, tears, urine and seminal fluid. -
序列相似性
Belongs to the cystatin family. -
细胞定位
Secreted. - Information by UniProt
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数据库链接
- Entrez Gene: 1469 Human
- Omim: 123855 Human
- SwissProt: P01037 Human
- Unigene: 123114 Human
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别名
- CST1 antibody
- Cystain SAI antibody
- Cystain-SA-I antibody
see all
图片
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Cystatin SN/CST1 antibody (ab124281)
ab124281, at 5µg/ml, staining Cystatin SN/CST1 in formalin-fixed, paraffin-embedded Human prostate tissue.
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Immunocytochemistry/ Immunofluorescence - Anti-Cystatin SN/CST1 antibody (ab124281)Immunofluorescence analysis of MCF7 cells, using ab124281at 1/100 dilution. The picture on the right is treated with the synthesized peptide.
实验方案
数据表及文件
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SDS download
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Datasheet download
文献 (2)
ab124281 被引用在 2 文献中.
- Zhao M et al. Weighted Correlation Network Analysis of Cancer Stem Cell-Related Prognostic Biomarkers in Esophageal Squamous Cell Carcinoma. Technol Cancer Res Treat 21:15330338221117003 (2022). PubMed: 35899307
- Gao W et al. Psoralen inhibits the inflammatory response and mucus production in allergic rhinitis by inhibiting the activator protein 1 pathway and the downstream expression of cystatin‑SN. Mol Med Rep 24:N/A (2021). PubMed: 34278468