Anti-CYP2A6抗体[F16 P2 D8] (ab56069)
![Western blot - Anti-CYP2A6 antibody [F16 P2 D8] (ab56069)](https://www.abcam.cn/ps/products/56/ab56069/Images/ab56069-69405-anti-cytochrome-p450-2a6-antibody-f16-p2-d8-western-blot.jpg "Western blot - Anti-CYP2A6 antibody [F16 P2 D8] (ab56069)")
Key features and details
- Mouse monoclonal [F16 P2 D8] to CYP2A6
- Suitable for: WB, IHC-P
- Reacts with: Human
- Isotype: IgG1
概述
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产品名称
Anti-CYP2A6抗体[F16 P2 D8]
参阅全部 CYP2A6 一抗 -
描述
小鼠单克隆抗体[F16 P2 D8] to CYP2A6 -
宿主
Mouse -
经测试应用
适用于: WB, IHC-Pmore details -
种属反应性
与反应: Human -
免疫原
Synthetic peptide corresponding to Human CYP2A6 (C terminal) conjugated to ovalbumin.
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常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles. -
存储溶液
Preservative: 0.08% Sodium azide
Constituent: PBS -
Concentration information loading... -
纯度
Protein G purified -
克隆
单克隆 -
克隆编号
F16 P2 D8 -
骨髓瘤
Ag8.653 -
同种型
IgG1 -
研究领域
相关产品
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Compatible Secondaries
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Isotype control
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab56069于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度；实际最佳的稀释度/浓度应由使用者检定。
| 应用 | Ab评论 | 说明 |
|---|---|---|
| WB |
Use a concentration of 1 - 2 µg/ml. Detects a band of approximately 54 kDa (predicted molecular weight: 57 kDa).
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| IHC-P |
Use a concentration of 1 µg/ml.
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| 说明 |
|---|
|
WB
Use a concentration of 1 - 2 µg/ml. Detects a band of approximately 54 kDa (predicted molecular weight: 57 kDa). |
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IHC-P
Use a concentration of 1 µg/ml. |
靶标
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功能
Exhibits a high coumarin 7-hydroxylase activity. Can act in the hydroxylation of the anti-cancer drugs cyclophosphamide and ifosphamide. Competent in the metabolic activation of aflatoxin B1. Constitutes the major nicotine C-oxidase. Possesses low phenacetin O-deethylation activity. -
组织特异性
Liver. -
序列相似性
Belongs to the cytochrome P450 family. -
细胞定位
Endoplasmic reticulum membrane. Microsome membrane. - Information by UniProt
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数据库链接
- Entrez Gene: 1548 Human
- Omim: 122720 Human
- SwissProt: P11509 Human
- Unigene: 250615 Human
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别名
- Coumarin 7 hydroxylase antibody
- Coumarin 7-hydroxylase antibody
- CP2A6_HUMAN antibody
see all
图片
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Western blot - Anti-CYP2A6 antibody [F16 P2 D8] (ab56069)Anti-CYP2A6 antibody [F16 P2 D8] (ab56069) at 1 µg/ml + Recombinant cytochrome p450
Predicted band size: 57 kDa
Observed band size: 54 kDa why is the actual band size different from the predicted? -
![Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-CYP2A6 antibody [F16 P2 D8] (ab56069)](https://www.abcam.cn/ps/products/56/ab56069/Images/ab56069-69404-anti-cytochrome-p450-2a6-antibody-f16-p2-d8-immunohistochemistry.jpg)
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-CYP2A6 antibody [F16 P2 D8] (ab56069)This image shows normal human liver tissue stained by ab56069 at 1µg/ml.
数据表及文件
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SDS download
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Datasheet download
文献 (1)
ab56069 被引用在 1 文献中.
- Dhamankar V et al. Gene expression and immunochemical localization of major cytochrome P450 drug-metabolizing enzymes in bovine nasal olfactory and respiratory mucosa. Inhal Toxicol 27:767-77 (2015). PubMed: 26572092