Anti-CXCR6抗体(ab125115)
Key features and details
- Goat polyclonal to CXCR6
- Suitable for: WB, IHC-P
- Reacts with: Human
- Isotype: IgG
概述
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产品名称
Anti-CXCR6抗体
参阅全部 CXCR6 一抗 -
描述
山羊多克隆抗体to CXCR6 -
宿主
Goat -
经测试应用
适用于: WB, IHC-Pmore details -
种属反应性
与反应: Human
预测可用于: Mouse, Rat, Dog
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免疫原
Synthetic peptide:
SEDNSKTFSASHN
with a Cysteine residue linker, corresponding to C terminal amino acids 321-333 of Human Bonzo (NP_006555.1). -
阳性对照
- Human thymus tissue; HEK293 lysate.
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常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles. -
存储溶液
pH: 7.30
Preservative: 0.02% Sodium azide
Constituents: 0.5% BSA, 99% Tris buffered saline -
Concentration information loading... -
纯度
Immunogen affinity purified -
克隆
多克隆 -
同种型
IgG -
研究领域
相关产品
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Compatible Secondaries
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Isotype control
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab125115于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度；实际最佳的稀释度/浓度应由使用者检定。
| 应用 | Ab评论 | 说明 |
|---|---|---|
| WB |
Use a concentration of 0.3 - 1 µg/ml. Predicted molecular weight: 39 kDa.
|
|
| IHC-P |
Use a concentration of 3.75 µg/ml. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.
|
| 说明 |
|---|
|
WB
Use a concentration of 0.3 - 1 µg/ml. Predicted molecular weight: 39 kDa. |
|
IHC-P
Use a concentration of 3.75 µg/ml. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol. |
靶标
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功能
Receptor for the C-X-C chemokine CXCL16. Used as a coreceptor by SIVs and by strains of HIV-2 and m-tropic HIV-1. -
组织特异性
Expressed in lymphoid tissues and activated T cells. -
序列相似性
Belongs to the G-protein coupled receptor 1 family. -
细胞定位
Cell membrane. - Information by UniProt
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数据库链接
- Entrez Gene: 10663 Human
- Entrez Gene: 80901 Mouse
- Entrez Gene: 100124593 Rat
- Omim: 605163 Human
- SwissProt: O00574 Human
- SwissProt: Q9EQ16 Mouse
- Unigene: 34526 Human
- Unigene: 124289 Mouse
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别名
- bonzo antibody
- C X C chemokine receptor type 6 antibody
- C-X-C chemokine receptor type 6 antibody
see all
图片
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-CXCR6 antibody (ab125115)
ab125115, at 3.75µg/ml, staining CXCR6 in formalin-fixed, paraffin-embedded Human thymus tissue by Immunohistochemistry.
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Western blot - Anti-CXCR6 antibody (ab125115)Anti-CXCR6 antibody (ab125115) at 1 µg/ml + HEK293 lysate (in RIPA buffer) at 35 µg
Developed using the ECL technique.
Predicted band size: 39 kDa
Exposure time: 1 hour
数据表及文件
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Datasheet download
文献 (2)
ab125115 被引用在 2 文献中.
- Hald SM et al. Prognostic impact of CXCL16 and CXCR6 in non-small cell lung cancer: combined high CXCL16 expression in tumor stroma and cancer cells yields improved survival. BMC Cancer 15:441 (2015). IHC . PubMed: 26021984
- Richardsen E et al. The prognostic significance of CXCL16 and its receptor C-X-C chemokine receptor 6 in prostate cancer. Am J Pathol 185:2722-30 (2015). PubMed: 26272362
