重组Anti-CXCL7/PBP抗体[EPR7767] (ab133252)
![Western blot - Anti-CXCL7/PBP antibody [EPR7767] (ab133252)](https://www.abcam.cn/ps/products/133/ab133252/Images/NAP2-Primary-antibodies-ab133252-1.JPG "Western blot - Anti-CXCL7/PBP antibody [EPR7767] (ab133252)")
Key features and details
- Produced recombinantly (animal-free) for high batch-to-batch consistency and long term security of supply
- Rabbit monoclonal [EPR7767] to CXCL7/PBP
- Suitable for: WB
- Reacts with: Human
Related conjugates and formulations
概述
-
产品名称
Anti-CXCL7/PBP抗体[EPR7767]
参阅全部 CXCL7/PBP 一抗 -
描述
兔单克隆抗体[EPR7767] to CXCL7/PBP -
宿主
Rabbit -
经测试应用
适用于: WBmore details
不适用于: IHC-P -
种属反应性
与反应: Human -
免疫原
Synthetic peptide. This information is proprietary to Abcam and/or its suppliers.
-
阳性对照
- Human platelet lysate
-
常规说明
This product is a recombinant monoclonal antibody, which offers several advantages including:
- - High batch-to-batch consistency and reproducibility
- - Improved sensitivity and specificity
- - Long-term security of supply
- - Animal-free production
Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb® patents.
Mouse, Rat: We have preliminary internal testing data to indicate this antibody may not react with these species. Please contact us for more information.
性能
-
形式
Liquid -
存放说明
Shipped at 4°C. Store at -20°C. Stable for 12 months at -20°C. -
解离常数（KD）
KD = 9.40 x 10 -12 M Learn more about KD -
存储溶液
pH: 7.20
Preservative: 0.01% Sodium azide
Constituents: 9% PBS, 40% Glycerol (glycerin, glycerine), 0.05% BSA, 50% Tissue culture supernatant -
Concentration information loading... -
纯度
Protein A purified -
克隆
单克隆 -
克隆编号
EPR7767 -
同种型
IgG -
研究领域
相关产品
-
Alternative Versions
-
Isotype control
-
Recombinant Protein
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab133252于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度；实际最佳的稀释度/浓度应由使用者检定。
| 应用 | Ab评论 | 说明 |
|---|---|---|
| WB |
1/1000 - 1/10000. Predicted molecular weight: 14 kDa.
|
| 说明 |
|---|
|
WB
1/1000 - 1/10000. Predicted molecular weight: 14 kDa. |
应用说明
Is unsuitable for IHC-P.
靶标
-
功能
LA-PF4 stimulates DNA synthesis, mitosis, glycolysis, intracellular cAMP accumulation, prostaglandin E2 secretion, and synthesis of hyaluronic acid and sulfated glycosaminoglycan. It also stimulates the formation and secretion of plasminogen activator by human synovial cells. NAP-2 is a ligand for CXCR1 and CXCR2, and NAP-2, NAP-2(73), NAP-2(74), NAP-2(1-66), and most potent NAP-2(1-63) are chemoattractants and activators for neutrophils. TC-1 and TC-2 are antibacterial proteins, in vitro released from activated platelet alpha-granules. CTAP-III(1-81) is more potent than CTAP-III desensitize chemokine-induced neutrophil activation. -
序列相似性
Belongs to the intercrine alpha (chemokine CxC) family. -
翻译后修饰
Proteolytic removal of residues 1-9 produces the active peptide connective tissue-activating peptide III (CTAP-III) (low-affinity platelet factor IV (LA-PF4)).
Proteolytic removal of residues 1-13 produces the active peptide beta-thromboglobulin, which is released from platelets along with platelet factor 4 and platelet-derived growth factor.
NAP-2(1-66) is produced by proteolytical processing, probably after secretion by leukocytes other than neutrophils.
NAP-2(73) and NAP-2(74) seem not be produced by proteolytical processing of secreted precursors but are released in an active form from platelets. -
细胞定位
Secreted. - Information by UniProt
-
数据库链接
- Entrez Gene: 5473 Human
- Omim: 121010 Human
- SwissProt: P02775 Human
- Unigene: 2164 Human
-
别名
- B TG1 antibody
- Beta TG antibody
- Beta thromboglobulin antibody
see all
图片
-
Western blot - Anti-CXCL7/PBP antibody [EPR7767] (ab133252)Anti-CXCL7/PBP antibody [EPR7767] (ab133252) at 1/1000 dilution + Human platelet lysate at 10 µg
Predicted band size: 14 kDa -
![OI-RD Scanning - Anti-CXCL7/PBP antibody [EPR7767] (ab133252)](https://www.abcam.cn/ps/products/133/ab133252/Images/NAP2-Primary-antibodies-ab133252-3.jpg)
OI-RD Scanning - Anti-CXCL7/PBP antibody [EPR7767] (ab133252) -
![Anti-CXCL7/PBP antibody [EPR7767] (ab133252)](https://www.abcam.cn/ps/products/133/ab133252/Images/ab133252-3-benefits-of-recombinant-antibodies.png)
Anti-CXCL7/PBP antibody [EPR7767] (ab133252)
数据表及文件
-
SDS download
-
Datasheet download
文献 (0)
ab133252 尚未被引用在任何文献中。