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AB12322

Anti-CSN4抗体

Anti-CSN4 antibody

5

(1 Review)

|

(4 Publications)

Rabbit Polyclonal CSN4 antibody. Suitable for WB and reacts with Mouse, Human samples. Cited in 4 publications. Immunogen corresponding to Synthetic Peptide within Human COPS4 aa 350-450.

查看别名

CSN4, COPS4, COP9 signalosome complex subunit 4, SGN4, Signalosome subunit 4, JAB1-containing signalosome subunit 4

1 Images
Western blot - Anti-CSN4 antibody (AB12322)
  • WB

Supplier Data

Western blot - Anti-CSN4 antibody (AB12322)

All lanes:

Western blot - Anti-CSN4 antibody (ab12322) at 0.1 µg/mL

Lane 1:

HeLa whole cell lysate at 50 µg

Lane 2:

HEK293T whole cell lysate at 50 µg

Lane 3:

Jurkat whole cell lysate at 50 µg

Lane 4:

TCMK-1 whole cell lysate at 50 µg

Lane 5:

NIH/3T3 whole cell lysate at 50 µg

Predicted band size: 46 kDa

false

Exposure time: 3min

关键信息

宿主种属

Rabbit

克隆

Polyclonal

亚型

IgG

不含载体蛋白

No

反应种属

Human, Mouse

应用

WB

applications

免疫原

Synthetic Peptide within Human COPS4 aa 350-450. The exact immunogen used to generate this antibody is proprietary information.

Q9BT78

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替代产品

Primary Antibodies

AB139688

Anti-CSN4 antibody [EPR7453]

RabMAb|Recombinant

Western blot - Anti-CSN4 antibody [EPR7453] (AB139688)

  • 0
  • 0

搭配使用产品

Primary Antibodies

AB34540

Anti-Torsin A/DYT1 antibody

Immunocytochemistry/ Immunofluorescence - Anti-Torsin A/DYT1 antibody (AB34540)

  • 5
  • 2
Primary Antibodies

AB215191

Anti-DFNA5/GSDME antibody [EPR19859] - N-terminal

20ul selling size|RabMAb|Recombinant|KO Validated

Western blot - Anti-DFNA5/GSDME antibody [EPR19859] - N-terminal (AB215191)

  • 5
  • 4
Primary Antibodies

AB203126

Anti-Hsp90 antibody [EPR16621-67]

RabMAb|Recombinant|Lab Essentials|20ul selling size

Immunocytochemistry/ Immunofluorescence - Anti-Hsp90 antibody [EPR16621-67] (AB203126)

  • 0
  • 0
Primary Antibodies

AB124779

Anti-CSN8 antibody [EPR5139]

RabMAb|Recombinant

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-CSN8 antibody [EPR5139] (AB124779)

  • 0
  • 0
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反应性数据

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "1/2000 - 1/10000", "WB-species-notes": "<p></p>" }, "Mouse": { "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "1/2000 - 1/10000", "WB-species-notes": "<p></p>" }, "Rat": { "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "" }, "Chicken": { "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "" }, "Chimpanzee": { "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "" }, "Cow": { "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "" }, "Dog": { "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "" }, "Guinea pig": { "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "" }, "Horse": { "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "" }, "Orangutan": { "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "" }, "Pig": { "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "" }, "Rabbit": { "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "" }, "Rhesus monkey": { "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "" }, "Turkey": { "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "" }, "Zebrafish": { "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "" } } }
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性能和储存信息

形式
Liquid
纯化工艺
Affinity purification Immunogen
纯化说明
Purified using the peptide immobilized on solid support.
存储溶液
pH: 7 - 8 Preservative: 0.1% Sodium azide Constituents: PBS, 1.815% Tris, 1.764% Sodium citrate
运输条件
Blue Ice
推荐的短期储存条件
+4°C
推荐的长期储存条件
+4°C
分装信息
Upon delivery aliquot
储存信息
Avoid freeze / thaw cycle
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产品实验方案

For this product, it's our understanding that no specific protocols are required. You can visit:
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靶点信息

Component of the COP9 signalosome complex (CSN), a complex involved in various cellular and developmental processes. The CSN complex is an essential regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunits of SCF-type E3 ligase complexes, leading to decrease the Ubl ligase activity of SCF-type complexes such as SCF, CSA or DDB2. Also involved in the deneddylation of non-cullin subunits such as STON2. The complex is also involved in phosphorylation of p53/TP53, c-jun/JUN, IkappaBalpha/NFKBIA, ITPK1, IRF8/ICSBP and SNAPIN, possibly via its association with CK2 and PKD kinases. CSN-dependent phosphorylation of TP53 and JUN promotes and protects degradation by the Ubl system, respectively.
See full target information COPS4
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文献 (4)

Recent publications for all applications. Explore the full list and refine your search

Cell cycle (Georgetown, Tex.) 18:1135-1153 PubMed31057046

2019

Inhibition of neddylation induces mitotic defects and alters MKLP1 accumulation at the midbody during cytokinesis.

Applications

Unspecified application

Species

Unspecified reactive species

Dudley Chung,Jayme Salsman,Graham Dellaire

Molecular endocrinology (Baltimore, Md.) 28:834-45 PubMed24725084

2014

COP9 subunits 4 and 5 target soluble guanylyl cyclase α1 and p53 in prostate cancer cells.

Applications

Unspecified application

Species

Unspecified reactive species

Meenakshi Bhansali,Lirim Shemshedini

Molecular and cellular biology 34:1066-76 PubMed24421388

2014

Dynamic regulation of the COP9 signalosome in response to DNA damage.

Applications

WB

Species

Human

Maria G Füzesi-Levi,Gili Ben-Nissan,Elisabetta Bianchi,Houjiang Zhou,Michael J Deery,Kathryn S Lilley,Yishai Levin,Michal Sharon

The Journal of biological chemistry 281:17457-65 PubMed16624822

2006

Jab1 induces the cytoplasmic localization and degradation of p53 in coordination with Hdm2.

Applications

Unspecified application

Species

Unspecified reactive species

Wonkyung Oh,Eun-Woo Lee,Young Hoon Sung,Mi-Ran Yang,Jaewang Ghim,Han-Woong Lee,Jaewhan Song
View all publications
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