Anti-CRSP2 / MED14抗体[2214C1a] (ab51349)
Key features and details
- Mouse monoclonal [2214C1a] to CRSP2 / MED14
- Suitable for: WB
- Reacts with: Recombinant fragment
- Isotype: IgG1
概述
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产品名称
Anti-CRSP2 / MED14抗体[2214C1a]
参阅全部 CRSP2 / MED14 一抗 -
描述
小鼠单克隆抗体[2214C1a] to CRSP2 / MED14 -
宿主
Mouse -
经测试应用
适用于: WBmore details -
种属反应性
与反应: Recombinant fragment -
免疫原
Recombinant human CRSP2/ MED14 fragment
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常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. -
存储溶液
pH: 7.40
Preservative: 0.05% Sodium azide
Constituents: 0.1312% Sodium phosphate, 0.0225% Potassium chloride, 1% BSA, 0.03% Potassium phosphate, 0.812% Sodium chloride, PBS -
Concentration information loading...
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纯度
Protein G purified -
纯化说明
Ab51349 was purified using protein G column chromatography from culture supernatant of hybridoma cultured in a medium containing bovine IgG depleted (approximately 95%) fetal bovine serum. -
克隆
单克隆 -
克隆编号
2214C1a -
同种型
IgG1 -
研究领域
相关产品
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Compatible Secondaries
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Isotype control
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab51349于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度;实际最佳的稀释度/浓度应由使用者检定。
应用 | Ab评论 | 说明 |
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WB |
Use at an assay dependent concentration. Predicted molecular weight: 161 kDa.
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说明 |
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WB
Use at an assay dependent concentration. Predicted molecular weight: 161 kDa. |
靶标
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功能
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. -
组织特异性
Ubiquitous. -
序列相似性
Belongs to the Mediator complex subunit 14 family. -
细胞定位
Nucleus. - Information by UniProt
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别名
- Activator-recruited cofactor 150 kDa component antibody
- ARC150 antibody
- Cofactor required for Sp1 transcriptional activation subunit 2 antibody
see all
图片
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Anti-CRSP2 / MED14 antibody [2214C1a] (ab51349) + Recombinant CRSP2/MED14
Predicted band size: 161 kDa
Observed band size: 36 kDa why is the actual band size different from the predicted?
数据表及文件
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Datasheet download
文献 (1)
ab51349 被引用在 1 文献中.
- Englert NA et al. Epigenetic modification of histone 3 lysine 27: mediator subunit MED25 is required for the dissociation of polycomb repressive complex 2 from the promoter of cytochrome P450 2C9. J Biol Chem 290:2264-78 (2015). PubMed: 25391650