重组Anti-CPT1B抗体[EPR7838] (ab134135)
Key features and details
- Produced recombinantly (animal-free) for high batch-to-batch consistency and long term security of supply
- Rabbit monoclonal [EPR7838] to CPT1B
- Suitable for: WB
- Reacts with: Human
Related conjugates and formulations
概述
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产品名称
Anti-CPT1B抗体[EPR7838]
参阅全部 CPT1B 一抗 -
描述
兔单克隆抗体[EPR7838] to CPT1B -
宿主
Rabbit -
经测试应用
适用于: WBmore details
不适用于: IHC-P or IP -
种属反应性
与反应: Human -
免疫原
Synthetic peptide within Human CPT1B aa 650-750. The exact sequence is proprietary.
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阳性对照
- Human fetal heart lysate; Human fetal muscle lysate
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常规说明
This product is a recombinant monoclonal antibody, which offers several advantages including:
- - High batch-to-batch consistency and reproducibility
- - Improved sensitivity and specificity
- - Long-term security of supply
- - Animal-free production
Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb® patents.
Mouse, Rat: We have preliminary internal testing data to indicate this antibody may not react with these species. Please contact us for more information.
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Store at -20°C. -
解离常数(KD)
KD = 9.80 x 10 -11 M Learn more about KD -
存储溶液
pH: 7.2
Preservative: 0.01% Sodium azide
Constituents: 9% PBS, 40% Glycerol (glycerin, glycerine), 0.05% BSA, 50% Tissue culture supernatant -
Concentration information loading...
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纯度
Protein A purified -
克隆
单克隆 -
克隆编号
EPR7838 -
同种型
IgG -
研究领域
相关产品
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Alternative Versions
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Isotype control
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Recombinant Protein
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab134135于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度;实际最佳的稀释度/浓度应由使用者检定。
应用 | Ab评论 | 说明 |
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WB |
1/1000 - 1/10000. Predicted molecular weight: 87 kDa.
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说明 |
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WB
1/1000 - 1/10000. Predicted molecular weight: 87 kDa. |
靶标
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组织特异性
Strong expression in heart and skeletal muscle. No expression in liver and kidney. -
通路
Lipid metabolism; fatty acid beta-oxidation. -
序列相似性
Belongs to the carnitine/choline acetyltransferase family. -
细胞定位
Mitochondrion outer membrane. - Information by UniProt
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数据库链接
- Entrez Gene: 1375 Human
- Omim: 601987 Human
- SwissProt: Q92523 Human
- Unigene: 439777 Human
- Unigene: 609867 Human
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别名
- muscle isoform antibody
- Carnitine O palmitoyltransferase 1B antibody
- Carnitine O palmitoyltransferase I mitochondrial muscle isoform antibody
see all
图片
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All lanes : Anti-CPT1B antibody [EPR7838] (ab134135) at 1/1000 dilution
Lane 1 : Human fetal heart lysate
Lane 2 : Human fetal muscle lysate
Lysates/proteins at 10 µg per lane.
Secondary
All lanes : HRP labelled goat anti rabbit at 1/2000 dilution
Predicted band size: 87 kDa
数据表及文件
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SDS download
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Datasheet download
文献 (9)
ab134135 被引用在 9 文献中.
- Jiang C et al. Targeting c-Jun inhibits fatty acid oxidation to overcome tamoxifen resistance in estrogen receptor-positive breast cancer. Cell Death Dis 14:653 (2023). PubMed: 37803002
- Weber CM et al. Induced pluripotent stem cell-derived cells model brain microvascular endothelial cell glucose metabolism. Fluids Barriers CNS 19:98 (2022). PubMed: 36494870
- Fox CD et al. Frequent Manipulation of Resistance Training Variables Promotes Myofibrillar Spacing Changes in Resistance-Trained Individuals. Front Physiol 12:773995 (2021). PubMed: 34975527
- Huang D et al. Multiomic analysis identifies CPT1A as a potential therapeutic target in platinum-refractory, high-grade serous ovarian cancer. Cell Rep Med 2:100471 (2021). PubMed: 35028612
- Warren JL et al. Exercise Effects on Mitochondrial Function and Lipid Metabolism during Energy Balance. Med Sci Sports Exerc 52:827-834 (2020). PubMed: 31652245
- Che L et al. Valine increases milk fat synthesis in mammary gland of gilts through stimulating AKT/MTOR/SREBP1 pathway‡. Biol Reprod N/A:N/A (2019). PubMed: 30985894
- Jakobsgaard JE et al. Impact of blood flow-restricted bodyweight exercise on skeletal muscle adaptations. Clin Physiol Funct Imaging N/A:N/A (2018). PubMed: 29446524
- Warren JL et al. Effects of acute hyperinsulinemia on skeletal muscle mitochondrial function, reactive oxygen species production, and metabolism in premenopausal women. Metabolism 77:1-12 (2017). PubMed: 29132536
- Gejl KD et al. No Superior Adaptations to Carbohydrate Periodization in Elite Endurance Athletes. Med Sci Sports Exerc 49:2486-2497 (2017). PubMed: 28723843