Anti-CPI-17抗体(ab131451)
Key features and details
- Rabbit polyclonal to CPI-17
- Suitable for: ICC/IF
- Reacts with: Human
- Isotype: IgG
概述
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产品名称
Anti-CPI-17抗体
参阅全部 CPI-17 一抗 -
描述
兔多克隆抗体to CPI-17 -
宿主
Rabbit -
经测试应用
适用于: ICC/IFmore details -
种属反应性
与反应: Human -
免疫原
Synthetic peptide corresponding to Human CPI-17 aa 36-40 (internal sequence) conjugated to keyhole limpet haemocyanin.
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阳性对照
- Methanol fixed HeLa cells.
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常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Store at -20°C. Stable for 12 months at -20°C. -
存储溶液
pH: 7.40
Preservative: 0.02% Sodium azide
Constituents: 49% PBS, 50% Glycerol (glycerin, glycerine), 0.88% Sodium chloride
PBS without Mg2+ and Ca2+ -
Concentration information loading...
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纯度
Immunogen affinity purified -
纯化说明
ab131451 was purified by affinity chromatography using epitope specific peptide. -
克隆
多克隆 -
同种型
IgG -
研究领域
相关产品
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Compatible Secondaries
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Isotype control
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Recombinant Protein
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab131451于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度;实际最佳的稀释度/浓度应由使用者检定。
应用 | Ab评论 | 说明 |
---|---|---|
ICC/IF |
1/100 - 1/200.
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说明 |
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ICC/IF
1/100 - 1/200. |
靶标
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功能
Inhibitor of PPP1CA. Has over 1000-fold higher inhibitory activity when phosphorylated, creating a molecular switch for regulating the phosphorylation status of PPP1CA substrates and smooth muscle contraction. -
组织特异性
Isoform 1 is detected in aorta and testis. Isoform 2 is detected in aorta. -
序列相似性
Belongs to the PP1 inhibitor family. -
细胞定位
Cytoplasm. - Information by UniProt
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数据库链接
- Entrez Gene: 94274 Human
- Omim: 608153 Human
- SwissProt: Q96A00 Human
- Unigene: 631569 Human
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别名
- 17 kDa PKC-potentiated inhibitory protein of PP1 antibody
- 17-KDa protein antibody
- 17kDa PKC potentiated inhibitory protein of PP1 antibody
see all
图片
数据表及文件
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SDS download
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Datasheet download
文献 (2)
ab131451 被引用在 2 文献中.
- Chen J et al. MiRNA-26a-5p inhibits preterm labor initiation by targeting and regulating TRPC3 ion channel protein expression. Environ Toxicol 39:357-366 (2024). PubMed: 37755144
- Chen J et al. Roles and mechanisms of TRPC3 and the PLC?/PKC/CPI-17 signaling pathway in regulating parturition. Mol Med Rep 17:898-910 (2018). PubMed: 29115500