Anti-COPB2抗体(ab2915)

Anti-COPB2抗体
参阅全部 COPB2 一抗

兔多克隆抗体to COPB2

Rabbit

Detects coatomer-protein I beta (COP I beta).

与反应: Rat
预测可用于: Mouse, Cow, Cynomolgus monkey

Synthetic peptide corresponding to Rat COPB2 aa 494-511.
Sequence:

KVLAAQETHEGVTEDGIE

(Peptide available as ab4933)

Run BLAST with Run BLAST with

Liquid

Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.

Preservative: 0.05% Sodium azide
Constituents: 0.1% BSA, 99% PBS

Immunogen affinity purified

Coatomer proteins are involved in regulating transport between the endoplasmic reticulum (ER) and the Golgi complex and in intra-Golgi transport. There exist two coatomer-protein mechanisms (COP I and COP II) and although they have mechanistic parallels, they are molecularly distinct. The COP I coat is comprised of seven subunits (alpha-, beta-, beta'-, gamma-, delta-, epsilon-, and zeta-COP) in a complex called coatomer. Assembly of the coatomer (COP I) onto non-clathrin coated vesicles is regulated by ADP-ribosylation factor (ARF). Vesicle formation, budding, fusion, and disassembly is dependent on GDP-GTP exchange, COP I, and ARF. COP I has been shown to facilitate retrograde intracellular transport from the ER to the Golgi complex. By contrast, COP II facilitates anterograde transport between these subcellular organelles. COP II has been shown to be independently and selectively recruited to the ER relative to COP I subunits.

多克隆

IgG

• Signal Transduction
• Protein Trafficking
• Chaperones

• Signal Transduction
• Protein Trafficking
• Vesicle Transport
• Coat Proteins

• Goat Anti-Rabbit IgG H&L (Alexa Fluor® 488) (ab150077)
• Goat Anti-Rabbit IgG H&L (HRP) (ab205718)

• Rabbit IgG, polyclonal - Isotype Control (ChIP Grade) (ab171870)