Anti-Complement factor B抗体[M13/12] (ab106139)
Key features and details
- Mouse monoclonal [M13/12] to Complement factor B
- Suitable for: IP, WB
- Reacts with: Human
- Isotype: IgG1
概述
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产品名称
Anti-Complement factor B抗体[M13/12]
参阅全部 Complement factor B 一抗 -
描述
小鼠单克隆抗体[M13/12] to Complement factor B -
宿主
Mouse -
特异性
ab106139 recognizes complement factor B/Bb -
经测试应用
适用于: IP, WBmore details -
种属反应性
与反应: Human -
免疫原
Full length protein corresponding to Complement factor B. Complement factor B/Bb
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常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles. -
存储溶液
Preservative: 0.02% Sodium azide
Constituents: 0.1% BSA, PBS -
Concentration information loading... -
纯度
Protein G purified -
克隆
单克隆 -
克隆编号
M13/12 -
同种型
IgG1
相关产品
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Compatible Secondaries
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Isotype control
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Recombinant Protein
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab106139于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度；实际最佳的稀释度/浓度应由使用者检定。
| 应用 | Ab评论 | 说明 |
|---|---|---|
| IP |
Use at an assay dependent concentration.
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| WB |
Use at an assay dependent concentration.
|
| 说明 |
|---|
|
IP
Use at an assay dependent concentration. |
|
WB
Use at an assay dependent concentration. |
靶标
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相关性
Factor B which is part of the alternate pathway of the complement system is cleaved by factor D into 2 fragments: Ba and Bb. Bb, a serine protease, then combines with complement factor 3b to generate the C3 or C5 convertase. It has also been implicated in proliferation and differentiation of preactivated B-lymphocytes, rapid spreading of peripheral blood monocytes, stimulation of lymphocyte blastogenesis and lysis of erythrocytes. Ba inhibits the proliferation of preactivated B-lymphocytes. -
细胞定位
Plasma membrane and Secreted -
数据库链接
- Entrez Gene: 629 Human
- Omim: 138470 Human
- SwissProt: P00751 Human
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别名
- C3/C5 convertase antibody
- Complement factor B antibody
- Glycine-rich beta glycoprotein antibody
see all
数据表及文件
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SDS download
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Datasheet download
文献 (2)
ab106139 被引用在 2 文献中.
- Oppermann M et al. Elevated plasma levels of the immunosuppressive complement fragment Ba in renal failure. Kidney Int 40:939-47 (1991). PubMed: 1837062
- Oppermann M et al. Quantitation of components of the alternative pathway of complement (APC) by enzyme-linked immunosorbent assays. J Immunol Methods 133:181-90 (1990). PubMed: 2146321