Anti-COMMD4抗体(ab115169)
Key features and details
- Rabbit polyclonal to COMMD4
- Suitable for: WB
- Reacts with: Human
- Isotype: IgG
概述
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产品名称
Anti-COMMD4抗体 -
描述
兔多克隆抗体to COMMD4 -
宿主
Rabbit -
经测试应用
适用于: WBmore details -
种属反应性
与反应: Human
预测可用于: Horse, Chimpanzee, Rhesus monkey, Gorilla, Orangutan, Bat, Elephant
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免疫原
Synthetic peptide, corresponding to a region within amino acids 149 -199 of Human COMMD4 (Q9HOA8).
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阳性对照
- HeLa cell lysates.
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常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles. -
存储溶液
pH: 7
Preservative: 0.09% Sodium azide
Constituent: 99% Tris citrate/phosphate
pH 7 to 8. -
Concentration information loading... -
纯度
Immunogen affinity purified -
克隆
多克隆 -
同种型
IgG -
研究领域
相关产品
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Compatible Secondaries
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Isotype control
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Positive Controls
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab115169于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度；实际最佳的稀释度/浓度应由使用者检定。
| 应用 | Ab评论 | 说明 |
|---|---|---|
| WB |
1/2000 - 1/10000. Predicted molecular weight: 22 kDa.
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| 说明 |
|---|
|
WB
1/2000 - 1/10000. Predicted molecular weight: 22 kDa. |
靶标
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功能
Down-regulates activation of NF-kappa-B. -
组织特异性
Ubiquitous. -
序列相似性
Contains 1 COMM domain. - Information by UniProt
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数据库链接
- Entrez Gene: 54939 Human
- Omim: 616701 Human
- SwissProt: Q9H0A8 Human
- Unigene: 351327 Human
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别名
- COMD4_HUMAN antibody
- COMM domain containing 4 antibody
- COMM domain-containing protein 4 antibody
- COMMD4 antibody
图片
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Western blot - Anti-COMMD4 antibody (ab115169)All lanes : Anti-COMMD4 antibody (ab115169) at 0.4 µg/ml
Lane 1 : HeLa cell lysate at 50 µg
Lane 2 : HeLa cell lysate at 15 µg
Lane 3 : HeLa cell lysate at 5 µg
Lane 4 : 293T cell lysate at 50 µg
Predicted band size: 22 kDa
Exposure time: 10 seconds
数据表及文件
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SDS download
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Datasheet download
文献 (4)
ab115169 被引用在 4 文献中.
- Tang M et al. Targeting the COMMD4-H2B protein complex in lung cancer. Br J Cancer 129:2014-2024 (2023). PubMed: 37914802
- Healy MD et al. Structure of the endosomal Commander complex linked to Ritscher-Schinzel syndrome. Cell 186:2219-2237.e29 (2023). PubMed: 37172566
- Suraweera A et al. COMMD4 functions with the histone H2A-H2B dimer for the timely repair of DNA double-strand breaks. Commun Biol 4:484 (2021). PubMed: 33875784
- Suraweera A et al. Defining COMMD4 as an anti-cancer therapeutic target and prognostic factor in non-small cell lung cancer. Br J Cancer N/A:N/A (2020). PubMed: 32439936