Anti-Collagen V抗体(ab134800)
Key features and details
- Rabbit polyclonal to Collagen V
- Suitable for: IHC-P
- Reacts with: Human
- Isotype: IgG
概述
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产品名称
Anti-Collagen V抗体
参阅全部 Collagen V 一抗 -
描述
兔多克隆抗体to Collagen V -
宿主
Rabbit -
经测试应用
适用于: IHC-Pmore details -
种属反应性
与反应: Human
预测可用于: Cow, Mammals -
免疫原
This product was produced with the following immunogens:
Tissue, cells or virus corresponding to Human Collagen V. Collagen Type V purified from human placenta.
Tissue, cells or virus corresponding to Cow Collagen V. Collagen Type V purified from bovine placenta. -
阳性对照
- Human skin, dermal collagen
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常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. -
存储溶液
pH: 8.00
Preservative: 0.01% Sodium azide
Constituents: 4.77% Sodium borate, 0.43% Sodium chloride, 0.15% EDTA -
Concentration information loading...
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纯度
Immunogen affinity purified -
克隆
多克隆 -
同种型
IgG -
研究领域
相关产品
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Compatible Secondaries
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Isotype control
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab134800于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度;实际最佳的稀释度/浓度应由使用者检定。
应用 | Ab评论 | 说明 |
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IHC-P |
Use a concentration of 5 µg/ml. Perform heat mediated antigen retrieval before commencing with IHC staining protocol.
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说明 |
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IHC-P
Use a concentration of 5 µg/ml. Perform heat mediated antigen retrieval before commencing with IHC staining protocol. |
靶标
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功能
Type V collagen is a member of group I collagen (fibrillar forming collagen). It is a minor connective tissue component of nearly ubiquitous distribution. Type V collagen binds to DNA, heparan sulfate, thrombospondin, heparin, and insulin. -
疾病相关
Ehlers-Danlos syndrome 1
Ehlers-Danlos syndrome 2 -
序列相似性
Belongs to the fibrillar collagen family.
Contains 1 fibrillar collagen NC1 domain.
Contains 1 laminin G-like domain. -
结构域
The C-terminal propeptide, also known as COLFI domain, have crucial roles in tissue growth and repair by controlling both the intracellular assembly of procollagen molecules and the extracellular assembly of collagen fibrils. It binds a calcium ion which is essential for its function. -
翻译后修饰
Prolines at the third position of the tripeptide repeating unit (G-X-Y) are hydroxylated in some or all of the chains.
Sulfated on 40% of tyrosines. -
细胞定位
Secreted > extracellular space > extracellular matrix. - Information by UniProt
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数据库链接
- Entrez Gene: 282192 Cow
- Entrez Gene: 1289 Human
- Entrez Gene: 1290 Human
- Entrez Gene: 50509 Human
- Omim: 120190 Human
- Omim: 120215 Human
- Omim: 120216 Human
- SwissProt: P05997 Human
see all -
别名
- AB collagen antibody
- Alpha 1 type V collagen antibody
- Alpha 2 type V collagen antibody
see all
图片
数据表及文件
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SDS download
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Datasheet download
文献 (1)
ab134800 被引用在 1 文献中.
- Coulson-Thomas VJ Analysis of Cancer Stromal Reaction Using an O-ring Co-culture Assay. Bio Protoc 7:e2131 (2017). PubMed: 34458452