Anti-Clostridium botulinum Toxin B抗体[GR-3G7] (ab59715)
![Flow Cytometry - Anti-Clostridium botulinum Toxin B antibody [GR-3G7] (ab59715)](https://www.abcam.cn/ps/products/59/ab59715/Images/ab59715_1.jpg "Flow Cytometry - Anti-Clostridium botulinum Toxin B antibody [GR-3G7] (ab59715)")
Key features and details
- Mouse monoclonal [GR-3G7] to Clostridium botulinum Toxin B
- Suitable for: Flow Cyt, Competitive ELISA
- Reacts with: Clostridium botulinum
- Isotype: IgG1
概述
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产品名称
Anti-Clostridium botulinum Toxin B抗体[GR-3G7] -
描述
小鼠单克隆抗体[GR-3G7] to Clostridium botulinum Toxin B -
宿主
Mouse -
特异性
This antibody reacts with Clostridium botulinum Toxin B. -
经测试应用
适用于: Flow Cyt, Competitive ELISAmore details -
种属反应性
与反应: Clostridium botulinum -
免疫原
Genetic immunisation with cDNA encoding Clostridium botulinum Toxin B.
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常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle. -
存储溶液
pH: 7.20
Constituent: PBS -
Concentration information loading... -
纯度
Protein G purified -
克隆
单克隆 -
克隆编号
GR-3G7 -
同种型
IgG1 -
研究领域
相关产品
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Compatible Secondaries
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Isotype control
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab59715于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度；实际最佳的稀释度/浓度应由使用者检定。
| 应用 | Ab评论 | 说明 |
|---|---|---|
| Flow Cyt |
Use 1.2µg for 106 cells.
ab170190 - Mouse monoclonal IgG1, is suitable for use as an isotype control with this antibody. |
|
| Competitive ELISA |
1/200 - 1/400.
|
| 说明 |
|---|
|
Flow Cyt
Use 1.2µg for 106 cells. ab170190 - Mouse monoclonal IgG1, is suitable for use as an isotype control with this antibody. |
|
Competitive ELISA
1/200 - 1/400. |
靶标
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相关性
Botulinum toxin acts by inhibiting neurotransmitter release. It binds to peripheral neuronal synapses, is internalized and moves by retrograde transport up the axon into the spinal cord where it can move between postsynaptic and presynaptic neurons. It inhibits neurotransmitter release by acting as a zinc endopeptidase that cleaves the 76 Gln | Phe 77 bond of synaptobrevin 2. -
细胞定位
Secreted -
数据库链接
- SwissProt: P10844 Clostridium botulinum
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别名
- BoNT/B antibody
- Bontoxilysin B antibody
- BontoxilysinB antibody
see all
图片
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Flow Cytometry - Anti-Clostridium botulinum Toxin B antibody [GR-3G7] (ab59715)BOSC23 cells were transiently trans-fected with an expression vector encoding either Clostridium botulinum Toxin B (red curve) or an irrelevant protein (control transfectant). Binding of ab59715 was detected with a PE conjugated secondary antibody. A positive signal was obtained only with Clostridium botulinum Toxin B transfected cells.
数据表及文件
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Datasheet download
文献 (0)
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