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Anti-CLCA4抗体(ab121524)

Submit a review Q&A (1)
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-CLCA4 antibody (ab121524)

    Key features and details

    • Rabbit polyclonal to CLCA4
    • Suitable for: IHC-P
    • Reacts with: Human
    • Isotype: IgG

    概述

    • 产品名称

      Anti-CLCA4抗体
      参阅全部 CLCA4 一抗

    • 描述

      兔多克隆抗体to CLCA4

    • 宿主

      Rabbit

    • 经测试应用

      适用于: IHC-Pmore details

    • 种属反应性

      与反应: Human

    • 免疫原

      antigen sequence: WVGMVHFDST ATIVNKLIQI KSSDERNTLM AGLPTYPLGG TSICSGIKYA FQVIGELHSQ LDGSEVLLLT DGEDNTASSC IDEV, corresponding to amino acids 56-139 of Human CLCA4.

      Run BLAST with BLAST the sequence with ExPASy Run BLAST with BLAST the sequence with NCBI

    • 阳性对照

      • Human duodenum.

    • 常规说明

      The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.

      If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As

    性能

    • 形式

      Liquid

    • 存放说明

      Shipped at 4°C. Store at -20ºC.

    • 存储溶液

      pH: 7.20
      Preservative: 0.02% Sodium azide
      Constituents: PBS, 40% Glycerol (glycerin, glycerine)
    • Concentration information loading...

    • 纯度

      Immunogen affinity purified

    • 克隆

      多克隆

    • 同种型

      IgG

    • 研究领域

    应用

    The Abpromise guarantee

    Abpromise™承诺保证使用ab121524于以下的经测试应用

    “应用说明”部分 下显示的仅为推荐的起始稀释度；实际最佳的稀释度/浓度应由使用者检定。

    应用 Ab评论 说明
    IHC-P
    1/10 - 1/20. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.
    说明
    IHC-P
    1/10 - 1/20. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

    靶标

    • 功能

      May be involved in mediating calcium-activated chloride conductance.

    • 组织特异性

      Primarily expressed in the digestive tract, mainly in colon. Detected in smaller amounts in brain, urogenital organs, testis, and salivary and mammary glands. Highly expressed in the epithelial layer and submucosal gland of the inferior turbinate mucosa. Lower levels in the epithelial layer of nasal polyp.

    • 序列相似性

      Belongs to the CLCR family.
      Contains 1 VWFA domain.

    • 翻译后修饰

      Processed at a monobasic residue to yield a larger N-terminal and a smaller C-terminal cleavage products of 90 to 110 and 30 to 35 kDa, respectively.

    • 细胞定位

      Cell membrane. Apical cell membrane. Secreted. The C-terminus 30 kDa form is anchored to the membrane (By similarity). The N-terminus 110 kDa form is released from the membrane triggered by an unknown stimulus.
    • Information by UniProt

    • 数据库链接

      • 别名

        • 30 kDa form antibody
        • CaCC-2 antibody
        • Calcium-activated chloride channel family member 4 antibody
        • Calcium-activated chloride channel protein 2 antibody
        • Calcium-activated chloride channel regulator 4 antibody
        • Clca4 antibody
        • CLCA4_HUMAN antibody
        • hCaCC-2 antibody
        • hCLCA4 antibody
        see all

      图片

      • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-CLCA4 antibody (ab121524)
        Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-CLCA4 antibody (ab121524)
        ab121524, at 1/10 dilution, staining human duodenum by immunohistochemistry on paraffin embebbed tissues (IHC-P).

      文献 (0)

      发表研究结果有使用 ab121524？请让我们知道，以便我们可以引用本数据表中的参考文章。

      ab121524 尚未被引用在任何文献中。

      客户评价及客户问答

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      提交评价 提交问题

      Question

      Can this item Anti-CLCA4 antibody (ab121524) be used in WB?

      Read More
      Answer

      Thank you very much for your interest in ab121524.
      To our knowledge, ab121524 has not been tested in WB. Therefore, I can offer a discount off a future purchase if you buy ab121524 now, test it in WB and submit feedback to us in the form of an Abreview. It doesn’t matter whether the Abreview is positive or negative, we would just really like to receive your feedback. The discount would be to the value of: 1 free primary antibody off your next Abcam order.
      If you are interested in this offer, please follow these steps:
      1. Reply to this e-mail to let me know that you would like to proceed and test ab121524 in WB. I will then send a discount code. This code must be issued before purchasing ab121524 so please wait for my reply before ordering.
      2. Purchase ab121524 either by phone, fax, or online (www.abcam.com).
      3. Test it in WB.
      4. Let us know the results, positive or negative, using our Abreview system (this will take about 10 minutes and images are great if you have them!). To find out how to submit an Abreview, please visit: https://www.abcam.com/abreviews.
      5. After the review is submitted to us, the discount code becomes active. Simply place your new order by phone, fax, or on the web and mention the discount code. The discount can be redeemed for any primary antibody ordered and the discount code is valid for 4 months after issue. Please remember that submission of the Abreview is sufficient for the discount code to become active.
      We are always pleased to obtain feedback about our products and any information is greatly appreciated! Even if ab121524 turns out to be unsuitable for WB, you will still receive the discount on your next purchase after your Abreview has been submitted.
      Please let me know if you have any questions about this offer and I would be happy to help you further.
      The Terms and Conditions of this offer can be found at: www.abcam.com/collaborationdiscount.

      Read More

      Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
      For licensing inquiries, please contact partnerships@abcam.com