Anti-Chromogranin A抗体(ab17064)
Key features and details
- Rabbit polyclonal to Chromogranin A
- Suitable for: Sandwich ELISA, IHC-P
- Reacts with: Human
- Isotype: IgG
概述
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产品名称
Anti-Chromogranin A抗体
参阅全部 Chromogranin A 一抗 -
描述
兔多克隆抗体to Chromogranin A -
宿主
Rabbit -
经测试应用
适用于: Sandwich ELISA, IHC-Pmore details -
种属反应性
与反应: Human -
免疫原
C-terminal half of Chromogranin A, purified from urine of patients with carcinoid syndrome.
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阳性对照
- Pancreas
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常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C or -80°C. Avoid freeze / thaw cycle. -
存储溶液
pH: 7.3
Preservative: 0.05% Sodium azide
Constituent: 1% BSA -
Concentration information loading... -
纯度
Protein A purified -
克隆
多克隆 -
同种型
IgG -
研究领域
相关产品
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Compatible Secondaries
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Isotype control
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Recombinant Protein
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab17064于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度；实际最佳的稀释度/浓度应由使用者检定。
| 应用 | Ab评论 | 说明 |
|---|---|---|
| Sandwich ELISA |
Use a concentration of 0.5 µg/ml.
For sandwich ELISA, use this antibody as Detection with ab36997 as Capture. |
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| IHC-P |
1/25 - 1/50. Perform heat mediated antigen retrieval before commencing with IHC staining protocol.
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| 说明 |
|---|
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Sandwich ELISA
Use a concentration of 0.5 µg/ml. For sandwich ELISA, use this antibody as Detection with ab36997 as Capture. |
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IHC-P
1/25 - 1/50. Perform heat mediated antigen retrieval before commencing with IHC staining protocol. |
靶标
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功能
Pancreastatin strongly inhibits glucose induced insulin release from the pancreas. -
序列相似性
Belongs to the chromogranin/secretogranin protein family. -
翻译后修饰
Sulfated on tyrosine residues and/or contains sulfated glycans.
O-glycosylated with core 1 or possibly core 8 glycans. -
细胞定位
Secreted. Neuroendocrine and endocrine secretory granules. - Information by UniProt
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数据库链接
- Entrez Gene: 1113 Human
- Omim: 118910 Human
- SwissProt: P10645 Human
- Unigene: 150793 Human
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形式
According to the Swiss-Prot database, this protein has many different forms which correspond to various molecular weights; thus the possible variation from the predicted molecular weight of 51kDa. -
别名
- beta Granin antibody
- betagranin (N-terminal fragment of chromogranin A) antibody
- catestatin antibody
see all
图片
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Sandwich ELISA - Anti-Chromogranin A antibody (ab17064)
Standard Curve for Chromogranin A (Analyte: ab85486) dilution range 1pg/ml to 1ug/ml using Capture Antibody Mouse monoclonal [23A1] to Chromogranin A (ab36997) at 1ug/ml and Detector Antibody Rabbit polyclonal to Chromogranin A (ab17064) at 0.5ug/ml. Concentration of ab17064 may vary from lot to lot; please use this curve as guideline.
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Chromogranin A antibody (ab17064)ab17064 staining Chromogranin A in formalin-fixed, paraffin-embedded Human pancreas tissue by Immunohistochemistry.
数据表及文件
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SDS download
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Datasheet download
文献 (5)
ab17064 被引用在 5 文献中.
- Ferreira FP et al. Individuals with type 2 diabetes have higher density of small intestinal neurotensin-expressing cells. Mol Cell Biochem 478:2779-2787 (2023). PubMed: 36920577
- Palha AM et al. Differential GIP/GLP-1 intestinal cell distribution in diabetics' yields distinctive rearrangements depending on Roux-en-Y biliopancreatic limb length. J Cell Biochem 119:7506-7514 (2018). PubMed: 29761876
- Weis VG et al. Loss of MYO5B in mice recapitulates Microvillus Inclusion Disease and reveals an apical trafficking pathway distinct to neonatal duodenum. Cell Mol Gastroenterol Hepatol 2:131-157 (2016). PubMed: 27019864
- Qu X et al. Growth Factor Independence-1 (Gfi1) Is Required for Pancreatic Acinar Unit Formation and Centroacinar Cell Differentiation. Cell Mol Gastroenterol Hepatol 1:233-247.e1 (2015). PubMed: 28247862
- Saqui-Salces M et al. A high-fat diet regulates gastrin and acid secretion through primary cilia. FASEB J : (2012). IHC-P ; Mouse . PubMed: 22516298