Anti-Choline Acetyltransferase抗体(ab6168)
Key features and details
- Rabbit polyclonal to Choline Acetyltransferase
- Suitable for: IHC-FrFl
- Reacts with: Rat
- Isotype: IgG
选择批间可重复性更高的重组抗体
- 研究可靠 —— 各批次间结果一致且可重复
- 长期批量供应 —— 采用重组技术,可实现快速生产
- 首次实验即可成功 —— 经过大量验证确认了特异性
- 符合伦理标准 —— 产品不含动物成分
概述
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产品名称
Anti-Choline Acetyltransferase抗体
参阅全部 Choline Acetyltransferase 一抗 -
描述
兔多克隆抗体to Choline Acetyltransferase -
宿主
Rabbit -
特异性
Extensive immunohistochemistry indicates localisation to cholinergic nervous system only. Will stain cholinergic neurons in rat central and peripheral nervous systems. -
经测试应用
适用于: IHC-FrFlmore details -
种属反应性
与反应: Rat
预测可用于: Chicken, Human, Pig, Non human primates不与反应: Sheep
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免疫原
Synthetic peptide:
H-GLFSSYRLPGHTQDTLVAQKSS
conjugated to KLH by a Glutaraldehyde linker, corresponding to amino acids 168-189 of Choline Acetyltransferase. -
常规说明
This antibody appears to have identical characteristics to those described by Benecke et al (1993). The antigen is the same. It is an excellent reagent for immunohistochemistry for both peripheral and central nervous system, staining both cell bodies and nerve terminals.The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Add glycerol to a final volume of 50% for extra stability and aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle. -
Concentration information loading...
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纯度
Whole antiserum -
克隆
多克隆 -
同种型
IgG -
研究领域
相关产品
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Compatible Secondaries
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Isotype control
应用
应用 | Ab评论 | 说明 |
---|---|---|
IHC-FrFl |
Use at an assay dependent concentration.
|
说明 |
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IHC-FrFl
Use at an assay dependent concentration. |
靶标
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功能
Catalyzes the reversible synthesis of acetylcholine (ACh) from acetyl CoA and choline at cholinergic synapses. -
疾病相关
Myasthenic syndrome, congenital, 6, presynaptic -
序列相似性
Belongs to the carnitine/choline acetyltransferase family. - Information by UniProt
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数据库链接
- Entrez Gene: 1103 Human
- Entrez Gene: 396896 Pig
- Entrez Gene: 290567 Rat
- Omim: 118490 Human
- SwissProt: P28329 Human
- SwissProt: P13222 Pig
- SwissProt: P32738 Rat
- Unigene: 302002 Human
see all -
别名
- Acetyl CoA choline O acetyltransferase antibody
- Acetyl CoA:choline O acetyltransferase antibody
- ChAT antibody
see all
图片
数据表及文件
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Datasheet download
文献 (13)
ab6168 被引用在 13 文献中.
- Liu Z et al. Activation of Neural Modeling-Related Genes in the Heart of Mice after Gamma Irradiation. Comput Math Methods Med 2021:8522417 (2021). PubMed: 35003326
- Li L et al. Electro-Acupuncture Improve the Early Pattern Separation in Alzheimer's Disease Mice via Basal Forebrain-Hippocampus Cholinergic Neural Circuit. Front Aging Neurosci 13:770948 (2021). PubMed: 35185516
- Zhu Q et al. Neural stem cell transplantation improves learning and memory by protecting cholinergic neurons and restoring synaptic impairment in an amyloid precursor protein/presenilin 1 transgenic mouse model of Alzheimer's disease. Mol Med Rep 21:1172-1180 (2020). PubMed: 31922229
- Xiao Q et al. A new GABAergic somatostatin projection from the BNST onto accumbal parvalbumin neurons controls anxiety. Mol Psychiatry N/A:N/A (2020). PubMed: 32555286
- Kannan A et al. ZPR1 prevents R-loop accumulation, upregulates SMN2 expression and rescues spinal muscular atrophy. Brain 143:69-93 (2020). PubMed: 31828288