Anti-cGMP抗体(ab836)
Key features and details
- Sheep polyclonal to cGMP
- Suitable for: ELISA, RIA
- Isotype: IgG
选择批间可重复性更高的重组抗体
- 研究可靠 —— 各批次间结果一致且可重复
- 长期批量供应 —— 采用重组技术,可实现快速生产
- 首次实验即可成功 —— 经过大量验证确认了特异性
- 符合伦理标准 —— 产品不含动物成分
概述
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产品名称
Anti-cGMP抗体
参阅全部 cGMP 一抗 -
描述
羊多克隆抗体to cGMP -
宿主
Sheep -
特异性
This antibody reacts specifically with cyclic GMP. -
经测试应用
适用于: ELISA, RIAmore details -
免疫原
Full length protein corresponding to cGMP. Succinylated cGMP conjugated to bovine serum albumin.
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常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles. -
存储溶液
Preservative: 0.01% Sodium azide -
Concentration information loading...
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纯度
Whole antiserum -
克隆
多克隆 -
同种型
IgG -
研究领域
相关产品
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Isotype control
应用
应用 | Ab评论 | 说明 |
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ELISA |
Use at an assay dependent concentration.
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RIA |
Use at an assay dependent concentration.
Able to detect and quantitate cGMP; 50% binding is achieved with a 1:6,400 dilution. |
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AP |
Use at an assay dependent concentration.
|
说明 |
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ELISA
Use at an assay dependent concentration. |
RIA
Use at an assay dependent concentration. Able to detect and quantitate cGMP; 50% binding is achieved with a 1:6,400 dilution. |
AP
Use at an assay dependent concentration. |
靶标
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相关性
Cyclic guanosine monophosphate (cGMP) serves as a second messenger in a manner similar to that observed with cAMP. Peptide hormones, such as the natriuretic factors, activate receptors that are associated with membrane-bound guanylate cyclase (GC). Receptor activation of GC leads to the conversion of GTP to cGMP. Nitric oxide (NO) also stimulates cGMP production by activating soluble GC, perhaps by binding to the heme moiety of the enzyme. Similar to cAMP, cGMP mediates most of its intracellular effects through the activation of specific cGMP dependent protein kinases (PKG). -
别名
- Cyclic GMP antibody
- Cyclic guanosine monophosphate antibody
- Guanosine 3 5 Cyclic Monophosphate antibody
实验方案
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
数据表及文件
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Datasheet download
文献 (2)
ab836 被引用在 2 文献中.
- Wu W et al. Enhancing natriuretic peptide signaling in adipose tissue, but not in muscle, protects against diet-induced obesity and insulin resistance. Sci Signal 10:N/A (2017). PubMed: 28743802
- Yu L et al. A novel bioassay for the activity determination of therapeutic human brain natriuretic peptide (BNP). PLoS One 7:e49934 (2012). ELISA . PubMed: 23185490