CF405M Anti-CD42a/GP-IX抗体[GR-P] (ab119483)
![Flow Cytometry - CF405M Anti-CD42a/GP-IX antibody [GR-P] (ab119483)](https://www.abcam.cn/ps/products/119/ab119483/Images/ab119483-132798-anti-cd42a-gp-ix-antibody-gr-p-cf405m-flow-cytometry.jpg "Flow Cytometry - CF405M Anti-CD42a/GP-IX antibody [GR-P] (ab119483)")
Key features and details
- CF405M Mouse monoclonal [GR-P] to CD42a/GP-IX
- Suitable for: Flow Cyt
- Reacts with: Human
- Conjugation: CF405M. Ex: 408nm, Em: 452nm
- Isotype: IgG2a
概述
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产品名称
CF405M Anti-CD42a/GP-IX抗体[GR-P]
参阅全部 CD42a/GP-IX 一抗 -
描述
CF405M小鼠单克隆抗体[GR-P] to CD42a/GP-IX -
宿主
Mouse -
偶联物
CF405M. Ex: 408nm, Em: 452nm -
经测试应用
适用于: Flow Cytmore details -
种属反应性
与反应: Human -
免疫原
Tissue, cells or virus corresponding to CD42a/GP-IX. Human red blood cells and platelets
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阳性对照
- Human platelets in normal peripheral blood.
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常规说明
CF405M (Abs/Em Max: 408/450nm). Direct replacement for Pacific Blue dye®, BD Horizon™ V450.
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Store at +4°C. -
存储溶液
pH: 7.20
Preservative: 0.09% Sodium azide
Buffer containing antibody stabilizer solution. -
Concentration information loading... -
纯度
Immunogen affinity purified -
克隆
单克隆 -
克隆编号
GR-P -
同种型
IgG2a -
研究领域
相关产品
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Alternative Versions
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab119483于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度；实际最佳的稀释度/浓度应由使用者检定。
| 应用 | Ab评论 | 说明 |
|---|---|---|
| Flow Cyt |
Use 5µl for 106 cells.
ab126036 - Mouse monoclonal IgG2a, is suitable for use as an isotype control with this antibody. |
| 说明 |
|---|
|
Flow Cyt
Use 5µl for 106 cells. ab126036 - Mouse monoclonal IgG2a, is suitable for use as an isotype control with this antibody. |
靶标
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功能
The GPIb-V-IX complex functions as the vWF receptor and mediates vWF-dependent platelet adhesion to blood vessels. The adhesion of platelets to injured vascular surfaces in the arterial circulation is a critical initiating event in hemostasis. GP-IX may provide for membrane insertion and orientation of GP-Ib. -
疾病相关
Defects in GP9 are a cause of Bernard-Soulier syndrome (BSS) [MIM:231200]; also known as giant platelet disease (GPD). BSS patients have unusually large platelets and have a clinical bleeding tendency. -
序列相似性
Contains 1 LRR (leucine-rich) repeat.
Contains 1 LRRCT domain.
Contains 1 LRRNT domain. -
细胞定位
Membrane. - Information by UniProt
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数据库链接
- Entrez Gene: 2815 Human
- Omim: 173515 Human
- SwissProt: P14770 Human
- Unigene: 1144 Human
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别名
- CD42a antibody
- Glycoprotein 9 antibody
- Glycoprotein IX antibody
see all
图片
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Flow Cytometry - CF405M Anti-CD42a/GP-IX antibody [GR-P] (ab119483)
ab119483, at 5 µl/106 cells, staining CD42a/GP-IX in Human platelets from normal Human peripheral blood cells by Flow Cytometry. Total events were used for the analysis.
数据表及文件
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SDS download
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Datasheet download
文献 (0)
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