Anti-CEACAM3抗体(ab111736)
Key features and details
- Rabbit polyclonal to CEACAM3
- Suitable for: WB
- Reacts with: Human
- Isotype: IgG
概述
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产品名称
Anti-CEACAM3抗体
参阅全部 CEACAM3 一抗 -
描述
兔多克隆抗体to CEACAM3 -
宿主
Rabbit -
经测试应用
适用于: WBmore details -
种属反应性
与反应: Human -
免疫原
Recombinant protein fragment containing a sequence corresponding to a region within amino acids 55 and 241 of Human CEACAM3 (UniProt ID: P40198).
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阳性对照
- A431 whole cell lysate
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常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles. -
存储溶液
pH: 7.00
Preservative: 0.01% Thimerosal (merthiolate)
Constituents: 1.21% Tris, 0.75% Glycine, 20% Glycerol (glycerin, glycerine) -
Concentration information loading... -
纯度
Immunogen affinity purified -
克隆
多克隆 -
同种型
IgG -
研究领域
相关产品
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Compatible Secondaries
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Isotype control
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Recombinant Protein
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab111736于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度；实际最佳的稀释度/浓度应由使用者检定。
| 应用 | Ab评论 | 说明 |
|---|---|---|
| WB |
1/500 - 1/3000. Predicted molecular weight: 27 kDa.
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| 说明 |
|---|
|
WB
1/500 - 1/3000. Predicted molecular weight: 27 kDa. |
靶标
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功能
Major granulocyte receptor mediating recognition and efficient opsonin-independent phagocytosis of CEACAM-binding microorganisms, including Neissiria, Moxarella and Haemophilus species, thus playing an important role in the clearance of pathogens by the innate immune system. Responsible for RAC1 stimulation in the course of pathogen phagocytosis. -
组织特异性
CGM1a, the predominant CGM1 transcript, is granulocyte-specific. Not detected out of the granulocytic lineage, such as monocytes, lymphocytes, spleen, testis, colon, brain, liver, pancreas, thymus, ovary, placenta, skeletal muscle, prostate, small intestine, heart, lung and kidney. -
序列相似性
Belongs to the immunoglobulin superfamily. CEA family.
Contains 1 Ig-like V-type (immunoglobulin-like) domain. -
结构域
The cytosolic domain is involved in S100A9 interaction. -
翻译后修饰
Tyrosine-phosphorylated in response to microbial binding. Tyr-230 and Tyr-241 are both required for phosphorylation to be detected. -
细胞定位
Membrane. - Information by UniProt
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数据库链接
- Entrez Gene: 1084 Human
- Omim: 609142 Human
- SwissProt: P40198 Human
- Unigene: 11 Human
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别名
- carcinoembryonic antibody
- Carcinoembryonic antigen CGM1 antibody
- Carcinoembryonic antigen gene family member 1 antibody
see all
图片
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Western blot - Anti-CEACAM3 antibody (ab111736)Anti-CEACAM3 antibody (ab111736) at 1/1000 dilution + A431 whole cell lysate at 30 µg
Predicted band size: 27 kDa
12% SDS PAGE
数据表及文件
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SDS download
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Datasheet download
文献 (0)
ab111736 尚未被引用在任何文献中。