Anti-CDKN1A interacting zinc finger蛋白1/CIZ1抗体(ab172442)
Key features and details
- Mouse polyclonal to CDKN1A interacting zinc finger protein 1/CIZ1
- Suitable for: WB
- Reacts with: Human
- Isotype: IgG
概述
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产品名称
Anti-CDKN1A interacting zinc finger蛋白1/CIZ1抗体
参阅全部 CDKN1A interacting zinc finger protein 1/CIZ1 一抗 -
描述
小鼠多克隆抗体to CDKN1A interacting zinc finger蛋白1/CIZ1 -
宿主
Mouse -
经测试应用
适用于: WBmore details -
种属反应性
与反应: Human -
免疫原
Recombinant full length protein within Human CDKN1A interacting zinc finger protein 1/CIZ1 aa 1 to the C-terminus. The exact immunogen sequence used to generate this antibody is proprietary information. If additional detail on the immunogen is needed to determine the suitability of the antibody for your needs, please contact our Scientific Support team to discuss your requirements. (AAH21163.1)
Database link: Q9ULV3-3 -
阳性对照
- CDKN1A interacting zinc finger protein 1/CIZ1 transfected 293T cell lysate
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常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle. -
存储溶液
pH: 7.4
Constituent: 100% PBS -
Concentration information loading... -
纯度
Protein A purified -
克隆
多克隆 -
同种型
IgG -
研究领域
相关产品
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Compatible Secondaries
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Isotype control
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab172442于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度；实际最佳的稀释度/浓度应由使用者检定。
| 应用 | Ab评论 | 说明 |
|---|---|---|
| WB |
Use a concentration of 1 µg/ml. Predicted molecular weight: 91 kDa.
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| 说明 |
|---|
|
WB
Use a concentration of 1 µg/ml. Predicted molecular weight: 91 kDa. |
靶标
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功能
May regulate the subcellular localization of CIP/WAF1. -
疾病相关
Defects in CIZ1 may be a cause of adult onset primary cervical dystonia. Dystonia is defined by the presence of sustained involuntary muscle contractions, often leading to abnormal postures. Cervical dystonia or spasmodic torticollis, the most common form of focal dystonia, is characterized by involuntary contractions of the neck muscles, which produce abnormal posturing of the head upon the trunk. -
序列相似性
Contains 1 matrin-type zinc finger. -
细胞定位
Nucleus. - Information by UniProt
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数据库链接
- Entrez Gene: 25792 Human
- Omim: 116899 Human
- SwissProt: Q9ULV3 Human
- Unigene: 212395 Human
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别名
- CDKI antibody
- CDKN1A-interacting zinc finger protein 1 antibody
- Cip1-interacting zinc finger protein antibody
see all
图片
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Western blot - Anti-CDKN1A interacting zinc finger protein 1/CIZ1 antibody (ab172442)All lanes : Anti-CDKN1A interacting zinc finger protein 1/CIZ1 antibody (ab172442) at 1 µg/ml
Lane 1 : CDKN1A interacting zinc finger protein 1/CIZ1 transfected 293T cell line lysate
Lane 2 : Non-transfected 293T cell line lysate
Lysates/proteins at 15 µl per lane.
Predicted band size: 91 kDa
数据表及文件
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Datasheet download
文献 (2)
ab172442 被引用在 2 文献中.
- Xiao J et al. Consequences of Cre-mediated deletion of Ciz1 exon 5 in mice. FEBS Lett 592:3101-3110 (2018). PubMed: 30098009
- Xiao J et al. Motor phenotypes and molecular networks associated with germline deficiency of Ciz1. Exp Neurol 283:110-20 (2016). PubMed: 27163549
