Anti-CD74抗体[Bu45] (ab54428)
Key features and details
- Mouse monoclonal [Bu45] to CD74
- Suitable for: IHC-Fr, Flow Cyt (Intra), IP, ICC/IF, Flow Cyt, Functional Studies
- Reacts with: Human
- Isotype: IgG1
概述
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产品名称
Anti-CD74抗体[Bu45]
参阅全部 CD74 一抗 -
描述
小鼠单克隆抗体[Bu45] to CD74 -
宿主
Mouse -
经测试应用
适用于: IHC-Fr, Flow Cyt (Intra), IP, ICC/IF, Flow Cyt, Functional Studiesmore details -
种属反应性
与反应: Human -
免疫原
Tissue, cells or virus corresponding to Human CD74. B lymphoblastoid cell line HFB1.
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常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle. -
存储溶液
pH: 7.40
Preservative: 0.09% Sodium azide
Constituent: PBS -
Concentration information loading... -
纯度
Protein G purified -
纯化说明
Purified from tissue culture supernatant. -
克隆
单克隆 -
克隆编号
Bu45 -
骨髓瘤
Ag8.653 -
同种型
IgG1 -
研究领域
相关产品
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Compatible Secondaries
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Conjugation kits
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Isotype control
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Recombinant Protein
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab54428于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度；实际最佳的稀释度/浓度应由使用者检定。
| 应用 | Ab评论 | 说明 |
|---|---|---|
| IHC-Fr |
Use at an assay dependent concentration.
|
|
| Flow Cyt (Intra) |
Use at an assay dependent concentration.
ab170190 - Mouse monoclonal IgG1, is suitable for use as an isotype control with this antibody. |
|
| IP |
Use at an assay dependent concentration.
|
|
| ICC/IF |
Use at an assay dependent concentration.
|
|
| Flow Cyt |
Use at an assay dependent concentration.
ab170190 - Mouse monoclonal IgG1, is suitable for use as an isotype control with this antibody. |
|
| Functional Studies |
Use at an assay dependent concentration.
This product contains sodium azide, removal by dialysis is recommended prior to use in functional assays. |
| 说明 |
|---|
|
IHC-Fr
Use at an assay dependent concentration. |
|
Flow Cyt (Intra)
Use at an assay dependent concentration. ab170190 - Mouse monoclonal IgG1, is suitable for use as an isotype control with this antibody. |
|
IP
Use at an assay dependent concentration. |
|
ICC/IF
Use at an assay dependent concentration. |
|
Flow Cyt
Use at an assay dependent concentration. ab170190 - Mouse monoclonal IgG1, is suitable for use as an isotype control with this antibody. |
|
Functional Studies
Use at an assay dependent concentration. This product contains sodium azide, removal by dialysis is recommended prior to use in functional assays. |
靶标
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功能
Plays a critical role in MHC class II antigen processing by stabilizing peptide-free class II alpha/beta heterodimers in a complex soon after their synthesis and directing transport of the complex from the endoplasmic reticulum to the endosomal/lysosomal system where the antigen processing and binding of antigenic peptides to MHC class II takes place. Serves as cell surface receptor for the cytokine MIF. -
序列相似性
Contains 1 thyroglobulin type-1 domain. -
细胞定位
Cell membrane. Endoplasmic reticulum membrane. Golgi apparatus > trans-Golgi network. Endosome. Lysosome. Transits through a number of intracellular compartments in the endocytic pathway. It can either undergo proteolysis or reach the cell membrane. - Information by UniProt
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数据库链接
- Entrez Gene: 972 Human
- Omim: 142790 Human
- SwissProt: P04233 Human
- Unigene: 436568 Human
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别名
- CD 74 antibody
- CD74 antibody
- CD74 antigen (invariant polypeptide of major histocompatibility complex, class II antigen-associated) antibody
see all
实验方案
数据表及文件
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Datasheet download
文献 (0)
ab54428 尚未被引用在任何文献中。
