Anti-CD69抗体[H1.2F3] (ab25190)
Key features and details
- Armenian Hamster monoclonal [H1.2F3] to CD69
- Suitable for: IHC-FoFr, Flow Cyt, IP, Cellular Activation
- Reacts with: Mouse
- Isotype: IgG
Related conjugates and formulations
概述
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产品名称
Anti-CD69抗体[H1.2F3]
参阅全部 CD69 一抗 -
描述
亚美尼亚仓鼠单克隆抗体[H1.2F3] to CD69 -
宿主
Armenian hamster -
特异性
ab25190 recognises mouse CD69/Very Early Activation Antigen (VEA),. -
经测试应用
适用于: IHC-FoFr, Flow Cyt, IP, Cellular Activationmore details -
种属反应性
与反应: Mouse -
免疫原
Tissue/ cell preparation (Mouse) - Y245 mouse dendritic epidermal T cell line.
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常规说明
This antibody augments PMA-induced T-cell proliferation, and induces redirected lysis of Fc receptor-bearing target cells by NK cells.
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle. -
存储溶液
pH: 8.2
Constituent: 100% Borate buffered saline -
Concentration information loading... -
纯度
Affinity purified -
Primary antibody说明
This antibody augments PMA-induced T-cell proliferation, and induces redirected lysis of Fc receptor-bearing target cells by NK cells. -
克隆
单克隆 -
克隆编号
H1.2F3 -
同种型
IgG -
轻链类型
lambda -
研究领域
相关产品
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Alternative Versions
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Isotype control
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Recombinant Protein
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab25190于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度；实际最佳的稀释度/浓度应由使用者检定。
| 应用 | Ab评论 | 说明 |
|---|---|---|
| IHC-FoFr |
Use at an assay dependent concentration. PubMed: 22483694
|
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| Flow Cyt |
Use at an assay dependent concentration.
Pubmed:2838547 and Pubmed:2026886. ab18474 - Armenian Hamster monoclonal IgG, is suitable for use as an isotype control with this antibody. |
|
| IP |
Use at an assay dependent concentration.
Please see: Pubmed:2838547. |
|
| Cellular Activation |
Use at an assay dependent concentration.
T cell and NK cells. Please see: Pubmed:2838547 and Pubmed:2026886. |
| 说明 |
|---|
|
IHC-FoFr
Use at an assay dependent concentration. PubMed: 22483694 |
|
Flow Cyt
Use at an assay dependent concentration. Pubmed:2838547 and Pubmed:2026886. ab18474 - Armenian Hamster monoclonal IgG, is suitable for use as an isotype control with this antibody. |
|
IP
Use at an assay dependent concentration. Please see: Pubmed:2838547. |
|
Cellular Activation
Use at an assay dependent concentration. T cell and NK cells. Please see: Pubmed:2838547 and Pubmed:2026886. |
靶标
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功能
Involved in lymphocyte proliferation and functions as a signal transmitting receptor in lymphocytes, natural killer (NK) cells, and platelets. -
组织特异性
Expressed on the surface of activated T-cells, B-cells, natural killer cells, neutrophils, eosinophils, epidermal Langerhans cells and platelets. -
序列相似性
Contains 1 C-type lectin domain. -
发展阶段
Earliest inducible cell surface glycoprotein acquired during lymphoid activation. -
翻译后修饰
Constitutive Ser/Thr phosphorylation in both mature thymocytes and activated T-lymphocytes. -
细胞定位
Membrane. - Information by UniProt
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数据库链接
- Entrez Gene: 12515 Mouse
- SwissProt: P37217 Mouse
- Unigene: 74745 Mouse
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别名
- Activation inducer molecule (AIM/CD69) antibody
- Activation inducer molecule antibody
- AIM antibody
see all
实验方案
数据表及文件
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SDS download
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Datasheet download
文献 (2)
ab25190 被引用在 2 文献中.
- Aftabizadeh M et al. Potent antitumor effects of cell-penetrating peptides targeting STAT3 axis. JCI Insight 6:N/A (2021). PubMed: 33491667
- Ishizaki S et al. Role of CD69 in acute lung injury. Life Sci 90:657-65 (2012). IHC-FoFr ; Mouse . PubMed: 22483694