Anti-CD66b抗体[GM-2H6] (ab48589)
![Flow Cytometry - Anti-CD66b antibody [GM-2H6] (ab48589)](https://www.abcam.cn/ps/products/48/ab48589/Images/ab48589-61080-anti-cd66b-antibody-gm-2h6-flow-cytometry.jpg "Flow Cytometry - Anti-CD66b antibody [GM-2H6] (ab48589)")
Key features and details
- Mouse monoclonal [GM-2H6] to CD66b
- Suitable for: Flow Cyt
- Reacts with: Human
- Isotype: IgG1
概述
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产品名称
Anti-CD66b抗体[GM-2H6]
参阅全部 CD66b 一抗 -
描述
小鼠单克隆抗体[GM-2H6] to CD66b -
宿主
Mouse -
特异性
This antibody exclusively recognizes CD66b (CEACAM8). -
经测试应用
适用于: Flow Cytmore details -
种属反应性
与反应: Human -
免疫原
The complete extracellular region of human CD66b (CEACAM8) cDNA.
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阳性对照
- Flow Cyt: BOSC23 cells.
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常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Store at +4°C. -
Concentration information loading... -
纯度
Protein G purified -
纯化说明
The antibody was purified from cell culture supernatants. -
克隆
单克隆 -
克隆编号
GM-2H6 -
同种型
IgG1 -
研究领域
相关产品
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Compatible Secondaries
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Isotype control
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Recombinant Protein
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab48589于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度；实际最佳的稀释度/浓度应由使用者检定。
| 应用 | Ab评论 | 说明 |
|---|---|---|
| Flow Cyt |
| 说明 |
|---|
应用说明
cELISA: Use at an assay dependent dilution.
ELISA: Use at an assay dependent dilution.
Flow Cyt: Use at an assay dependent dilution.
Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
ELISA: Use at an assay dependent dilution.
Flow Cyt: Use at an assay dependent dilution.
Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
靶标
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组织特异性
Expressed in leukocytes of chronic myeloid Leukemia patients and bone marrow. -
序列相似性
Belongs to the immunoglobulin superfamily. CEA family.
Contains 2 Ig-like C2-type (immunoglobulin-like) domains.
Contains 1 Ig-like V-type (immunoglobulin-like) domain. -
细胞定位
Cell membrane. - Information by UniProt
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数据库链接
- Entrez Gene: 1088 Human
- Omim: 615747 Human
- SwissProt: P31997 Human
- Unigene: 41 Human
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别名
- Carcinoembryonic antigen CGM6 antibody
- Carcinoembryonic antigen gene family member 6 antibody
- Carcinoembryonic antigen related cell adhesion molecule 8 antibody
see all
图片
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Flow Cytometry - Anti-CD66b antibody [GM-2H6] (ab48589)Ab48589, staining CD66b (CEACAM8) by Flow Cytometry.
BOSC23 cells were transiently transfected with expression vectors containing either the cDNA of CEACAM1, CEACAM3-8 or PSG. The latter was expressed as a membrane bound fusion protein. Expression of the constructs was tested with monoclonal antibodies known to recognize the corresponding proteins (CEACAM1, 3, 4, 5 and 6: D14HD11; CEACAM7: BAC2; CEACAM8: Tet2; PSG: BAP3; green curves). An irrelevant monoclonal antibody served as a negative control (black curves). For specificity testing, ab48589 was tested on all CEACAM transfectants. A positive signal was obtained only with CEACAM8 (CD66b) transfected cells (red curve).
数据表及文件
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Datasheet download
文献 (1)
ab48589 被引用在 1 文献中.
- Yoon J et al. CD66b Regulates Adhesion and Activation of Human Eosinophils. J Immunol 179:8454-62 (2007). Human . PubMed: 18056392
