Key features and details
- Mouse monoclonal [GM-2H6] to CD66b
- Suitable for: Flow Cyt
- Reacts with: Human
- Isotype: IgG1
参阅全部 CD66b 一抗
描述小鼠单克隆抗体[GM-2H6] to CD66b
特异性This antibody exclusively recognizes CD66b (CEACAM8).
经测试应用适用于: Flow Cytmore details
The complete extracellular region of human CD66b (CEACAM8) cDNA.
- Flow Cyt: BOSC23 cells.
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存放说明Shipped at 4°C. Store at +4°C.
Concentration information loading...
纯度Protein G purified
纯化说明The antibody was purified from cell culture supernatants.
The Abpromise guarantee
ELISA: Use at an assay dependent dilution.
Flow Cyt: Use at an assay dependent dilution.
Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
组织特异性Expressed in leukocytes of chronic myeloid Leukemia patients and bone marrow.
序列相似性Belongs to the immunoglobulin superfamily. CEA family.
Contains 2 Ig-like C2-type (immunoglobulin-like) domains.
Contains 1 Ig-like V-type (immunoglobulin-like) domain.
- Information by UniProt
- Carcinoembryonic antigen CGM6 antibody
- Carcinoembryonic antigen gene family member 6 antibody
- Carcinoembryonic antigen related cell adhesion molecule 8 antibody
Ab48589, staining CD66b (CEACAM8) by Flow Cytometry.
BOSC23 cells were transiently transfected with expression vectors containing either the cDNA of CEACAM1, CEACAM3-8 or PSG. The latter was expressed as a membrane bound fusion protein. Expression of the constructs was tested with monoclonal antibodies known to recognize the corresponding proteins (CEACAM1, 3, 4, 5 and 6: D14HD11; CEACAM7: BAC2; CEACAM8: Tet2; PSG: BAP3; green curves). An irrelevant monoclonal antibody served as a negative control (black curves). For specificity testing, ab48589 was tested on all CEACAM transfectants. A positive signal was obtained only with CEACAM8 (CD66b) transfected cells (red curve).
ab48589 被引用在 1 文献中.
- Yoon J et al. CD66b Regulates Adhesion and Activation of Human Eosinophils. J Immunol 179:8454-62 (2007). Human . PubMed: 18056392