Anti-CD39抗体[IMG17B5F11] (ab178572)
Key features and details
- Mouse monoclonal [IMG17B5F11] to CD39
- Suitable for: WB, IHC-P
- Reacts with: Mouse, Rat, Human
- Isotype: IgG2b
选择批间可重复性更高的重组抗体
- 研究可靠 —— 各批次间结果一致且可重复
- 长期批量供应 —— 采用重组技术,可实现快速生产
- 首次实验即可成功 —— 经过大量验证确认了特异性
- 符合伦理标准 —— 产品不含动物成分
概述
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产品名称
Anti-CD39抗体[IMG17B5F11]
参阅全部 CD39 一抗 -
描述
小鼠单克隆抗体[IMG17B5F11] to CD39 -
宿主
Mouse -
经测试应用
适用于: WB, IHC-Pmore details -
种属反应性
与反应: Mouse, Rat, Human -
免疫原
Recombinant fragment corresponding to Human CD39 aa 102-208.
Sequence:GIYLTDCMERAREVIPRSQHQETPVYLGATAGMRLLRMESEELADRVLDV VERSLSNYPFDFQGARIITGQEEGAYGWITINYLLGKFSQKTRWFSIVPY ETNNQET
Database link: P49961 -
阳性对照
- Human, mouse and rat brain lysates; Human spleen tissue.
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常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle. -
存储溶液
pH: 7.40
Preservative: 0.05% Sodium azide
Constituents: 0.05% BSA, 99% PBS -
Concentration information loading...
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纯度
Protein G purified -
克隆
单克隆 -
克隆编号
IMG17B5F11 -
同种型
IgG2b -
轻链类型
lambda -
研究领域
相关产品
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Compatible Secondaries
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Isotype control
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Positive Controls
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Recombinant Protein
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Related Products
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab178572于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度;实际最佳的稀释度/浓度应由使用者检定。
应用 | Ab评论 | 说明 |
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WB |
Use a concentration of 0.5 - 5 µg/ml. Predicted molecular weight: 58 kDa.
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IHC-P |
Use a concentration of 5 µg/ml.
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说明 |
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WB
Use a concentration of 0.5 - 5 µg/ml. Predicted molecular weight: 58 kDa. |
IHC-P
Use a concentration of 5 µg/ml. |
靶标
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功能
In the nervous system, could hydrolyze ATP and other nucleotides to regulate purinergic neurotransmission. Could also be implicated in the prevention of platelet aggregation. Hydrolyzes ATP and ADP equally well. -
组织特异性
Expressed primarily on activated lymphoid cells. Also expressed in endothelial tissues. The vascular isoform and the placental isoform II are present in both placenta and umbilical vein, whereas placental isoform I is present in placenta only. -
序列相似性
Belongs to the GDA1/CD39 NTPase family. -
翻译后修饰
The N-terminus is blocked.
Palmitoylated in the N-terminal part. -
细胞定位
Membrane. - Information by UniProt
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数据库链接
- Entrez Gene: 953 Human
- Entrez Gene: 12495 Mouse
- Entrez Gene: 64519 Rat
- Omim: 601752 Human
- SwissProt: P49961 Human
- SwissProt: P55772 Mouse
- SwissProt: P97687 Rat
- Unigene: 576612 Human
see all -
形式
There are 3 isoforms produced by alternative splicing. -
别名
- ATPDase antibody
- CD 39 antibody
- CD39 antibody
see all
图片
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Immunohistochemical analysis of formalin-fixed, paraffin-embedded normal Human spleen tissue labeling CD39 with ab178572 at 5 µg/ml, followed by peroxidase-conjugate and DAB chromogen.
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All lanes : Anti-CD39 antibody [IMG17B5F11] (ab178572) at 1 µg/ml
Lane 1 : Human brain lysate
Lane 2 : Mouse brain lysate
Lane 3 : Rat brain lysate
Lane 4 : Recombinant Human CD39 protein fragment
Predicted band size: 58 kDa
数据表及文件
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Datasheet download
文献 (4)
ab178572 被引用在 4 文献中.
- Ferreira JM et al. High CD39 expression is associated with the non-muscle-invasive phenotype of human bladder cancer. Oncotarget 12:1580-1586 (2021). PubMed: 34381563
- Sohn R et al. Anti-Inflammatory Effects of Endogenously Released Adenosine in Synovial Cells of Osteoarthritis and Rheumatoid Arthritis Patients. Int J Mol Sci 22:N/A (2021). PubMed: 34445661
- Zhan Y et al. PLA2G4A promotes right-sided colorectal cancer progression by inducing CD39+?d Treg polarization. JCI Insight 6:N/A (2021). PubMed: 34283812
- Aliagas E et al. Is the purinergic pathway involved in the pathology of COPD? Decreased lung CD39 expression at initial stages of COPD. Respir Res 19:103 (2018). PubMed: 29807526