重组Anti-CD239/BCAM抗体[EPR4164] (ab111181)
![Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-CD239/BCAM antibody [EPR4164] (ab111181)](https://www.abcam.cn/ps/products/111/ab111181/Images/CD239-Primary-antibodies-ab111181-4.gif "Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-CD239/BCAM antibody [EPR4164] (ab111181)")
Key features and details
- Produced recombinantly (animal-free) for high batch-to-batch consistency and long term security of supply
- Rabbit monoclonal [EPR4164] to CD239/BCAM
- Suitable for: IHC-P
- Reacts with: Human
Related conjugates and formulations
概述
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产品名称
Anti-CD239/BCAM抗体[EPR4164]
参阅全部 CD239/BCAM 一抗 -
描述
兔单克隆抗体[EPR4164] to CD239/BCAM -
宿主
Rabbit -
经测试应用
适用于: IHC-Pmore details
不适用于: Flow Cyt,IP or WB -
种属反应性
与反应: Human -
免疫原
Synthetic peptide. This information is proprietary to Abcam and/or its suppliers.
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阳性对照
- Human Breast Carcinoma and Tonsil Tissues.
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常规说明
This product is a recombinant monoclonal antibody, which offers several advantages including:
- - High batch-to-batch consistency and reproducibility
- - Improved sensitivity and specificity
- - Long-term security of supply
- - Animal-free production
Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb® patents.
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Store at -20°C. Stable for 12 months at -20°C. -
存储溶液
pH: 7.20
Preservative: 0.05% Sodium azide
Constituents: 0.1% BSA, 40% Glycerol (glycerin, glycerine), 9.85% Tris glycine, 50% Tissue culture supernatant -
Concentration information loading... -
纯度
Protein A purified -
克隆
单克隆 -
克隆编号
EPR4164 -
同种型
IgG -
研究领域
相关产品
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Alternative Versions
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Isotype control
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab111181于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度；实际最佳的稀释度/浓度应由使用者检定。
| 应用 | Ab评论 | 说明 |
|---|---|---|
| IHC-P |
1/100 - 1/250. Perform heat mediated antigen retrieval via the pressure cooker method before commencing with IHC staining protocol.
|
| 说明 |
|---|
|
IHC-P
1/100 - 1/250. Perform heat mediated antigen retrieval via the pressure cooker method before commencing with IHC staining protocol. |
靶标
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功能
Laminin alpha-5 receptor. May mediate intracellular signaling. -
组织特异性
Wide tissue distribution (highest in the pancreas and very low in brain). Closely associated with the basal layer of cells in epithelia and the endothelium of blood vessel walls. -
序列相似性
Contains 3 Ig-like C2-type (immunoglobulin-like) domains.
Contains 2 Ig-like V-type (immunoglobulin-like) domains. -
发展阶段
Is under developmental control in liver and may also be regulated during differentiation in other tissues. Up-regulated following malignant transformation in some cell types. -
翻译后修饰
Epinephrine-stimulated phosphorylation of Ser-621 by PKA enhances adhesion to laminin. -
细胞定位
Membrane. - Information by UniProt
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数据库链接
- Entrez Gene: 4059 Human
- Omim: 612773 Human
- SwissProt: P50895 Human
- Unigene: 625725 Human
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别名
- Antigen identified by monoclonal antibody F8 antibody
- AU antibody
- Auberger B antigen antibody
see all
图片
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-CD239/BCAM antibody [EPR4164] (ab111181)
ab111181 at 1/100 dilution staining CD239/BCAM in Paraffin-embedded Human breast carcinoma tissue by Immunohistochemistry.
Perform heat mediated antigen retrieval via the pressure cooker method before commencing with IHC staining protocol.
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![Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-CD239/BCAM antibody [EPR4164] (ab111181)](https://www.abcam.cn/ps/products/111/ab111181/Images/CD239-Primary-antibodies-ab111181-5.gif)
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-CD239/BCAM antibody [EPR4164] (ab111181)ab111181 at 1/100 dilution staining CD239/BCAM in Paraffin-embedded Human tonsil tissue by Immunohistochemistry.
Perform heat mediated antigen retrieval via the pressure cooker method before commencing with IHC staining protocol.
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![Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-CD239/BCAM antibody [EPR4164] (ab111181)](https://www.abcam.cn/ps/products/111/ab111181/Images/ab111181-124483-anti-cd239-antibody-epr4164-immunohistochemistry.jpg)
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-CD239/BCAM antibody [EPR4164] (ab111181)ab111181 showing positive staining in Thyroid gland carcinoma tissue.
Perform heat mediated antigen retrieval via the pressure cooker method before commencing with IHC staining protocol.
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![Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-CD239/BCAM antibody [EPR4164] (ab111181)](https://www.abcam.cn/ps/products/111/ab111181/Images/CD239-Primary-antibodies-ab111181-7.jpg)
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-CD239/BCAM antibody [EPR4164] (ab111181)ab111181 showing positive staining in Normal stomach tissue.
Perform heat mediated antigen retrieval via the pressure cooker method before commencing with IHC staining protocol.
-
![Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-CD239/BCAM antibody [EPR4164] (ab111181)](https://www.abcam.cn/ps/products/111/ab111181/Images/CD239-Primary-antibodies-ab111181-8.jpg)
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-CD239/BCAM antibody [EPR4164] (ab111181)ab111181 showing positive staining in Normal ovary tissue.
Perform heat mediated antigen retrieval via the pressure cooker method before commencing with IHC staining protocol.
-
![Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-CD239/BCAM antibody [EPR4164] (ab111181)](https://www.abcam.cn/ps/products/111/ab111181/Images/CD239-Primary-antibodies-ab111181-9.jpg)
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-CD239/BCAM antibody [EPR4164] (ab111181)ab111181 showing positive staining in Normal liver tissue.
Perform heat mediated antigen retrieval via the pressure cooker method before commencing with IHC staining protocol.
-
![Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-CD239/BCAM antibody [EPR4164] (ab111181)](https://www.abcam.cn/ps/products/111/ab111181/Images/CD239-Primary-antibodies-ab111181-10.jpg)
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-CD239/BCAM antibody [EPR4164] (ab111181)ab111181 showing positive staining in Normal kidney tissue.
Perform heat mediated antigen retrieval via the pressure cooker method before commencing with IHC staining protocol.
-
![Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-CD239/BCAM antibody [EPR4164] (ab111181)](https://www.abcam.cn/ps/products/111/ab111181/Images/CD239-Primary-antibodies-ab111181-11.jpg)
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-CD239/BCAM antibody [EPR4164] (ab111181)ab111181 showing positive staining in Hepatocellular carcinoma tissue.
Perform heat mediated antigen retrieval via the pressure cooker method before commencing with IHC staining protocol.
-
![Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-CD239/BCAM antibody [EPR4164] (ab111181)](https://www.abcam.cn/ps/products/111/ab111181/Images/CD239-Primary-antibodies-ab111181-12.jpg)
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-CD239/BCAM antibody [EPR4164] (ab111181)ab111181 showing negative staining in Normal heart tissue.
Perform heat mediated antigen retrieval via the pressure cooker method before commencing with IHC staining protocol.
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![Anti-CD239/BCAM antibody [EPR4164] (ab111181)](https://www.abcam.cn/ps/products/111/ab111181/Images/ab111181-10-benefits-of-recombinant-antibodies.png)
Anti-CD239/BCAM antibody [EPR4164] (ab111181)
数据表及文件
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SDS download
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Datasheet download
文献 (1)
ab111181 被引用在 1 文献中.
- Tang R et al. Differentiation of human induced pluripotent stem cells into nucleus pulposus-like cells. Stem Cell Res Ther 9:61 (2018). PubMed: 29523190