Anti-CD21抗体[B-E5] - BSA and Azide free (ab46900)
![Flow Cytometry - Anti-CD21 antibody [B-E5] (ab46900)](https://www.abcam.cn/ps/products/46/ab46900/Images/ab46900.gif "Flow Cytometry - Anti-CD21 antibody [B-E5] (ab46900)")
Key features and details
- Mouse monoclonal [B-E5] to CD21 - BSA and Azide free
- Suitable for: Flow Cyt
- Reacts with: Human
- Isotype: IgG2a
概述
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产品名称
Anti-CD21抗体[B-E5] - BSA and Azide free
参阅全部 CD21 一抗 -
描述
小鼠单克隆抗体[B-E5] to CD21 - BSA and Azide free -
宿主
Mouse -
特异性
This antibody is specific for CD21. (Recognises the soluble antigen). -
经测试应用
适用于: Flow Cytmore details -
种属反应性
与反应: Human -
免疫原
Tissue, cells or virus corresponding to Human CD21. Daudi cell line
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阳性对照
- human lymphocytes
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常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle. -
存储溶液
pH: 7.30
Constituent: 100% PBS
Sterile-filtered through 0.22 µm. Carrier and preservative free -
无载体
是 -
Concentration information loading... -
纯度
Ion Exchange Chromatography -
纯化说明
Sterile-filtered through 0.22 µm and treated to remove endotoxins. Carrier and preservative free. -
克隆
单克隆 -
克隆编号
B-E5 -
骨髓瘤
x63-Ag8.653 -
同种型
IgG2a -
轻链类型
kappa -
研究领域
相关产品
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Compatible Secondaries
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Isotype control
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab46900于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度；实际最佳的稀释度/浓度应由使用者检定。
| 应用 | Ab评论 | 说明 |
|---|---|---|
| Flow Cyt |
| 说明 |
|---|
应用说明
Flow Cyt: Use at an assay dependent dilution.
Induces human B lymphocytes proliferation
Competes with EBV for CD21 binding
Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
Induces human B lymphocytes proliferation
Competes with EBV for CD21 binding
Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
靶标
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功能
Receptor for complement C3Dd, for the Epstein-Barr virus on human B-cells and T-cells and for HNRPU. Participates in B lymphocytes activation. -
组织特异性
Mature B-lymphocytes, T-lymphocytes, pharyngeal epithelial cells, astrocytes and follicular dendritic cells of the spleen. -
疾病相关
Genetic variations in CR2 are associated with susceptibility to systemic lupus erythematosus type 9 (SLEB9) [MIM:610927]. Systemic lupus erythematosus (SLE) is a chronic autoimmune disease with a complex genetic basis. SLE is an inflammatory, and often febrile multisystemic disorder of connective tissue characterized principally by involvement of the skin, joints, kidneys, and serosal membranes. It is thought to represent a failure of the regulatory mechanisms of the autoimmune system. -
序列相似性
Belongs to the receptors of complement activation (RCA) family.
Contains 15 Sushi (CCP/SCR) domains. -
细胞定位
Membrane. - Information by UniProt
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数据库链接
- Entrez Gene: 1380 Human
- Omim: 120650 Human
- SwissProt: P20023 Human
- Unigene: 445757 Human
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别名
- C3DR antibody
- CD 21 antibody
- CD21 antibody
see all
图片
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Flow Cytometry - Anti-CD21 antibody [B-E5] (ab46900)A typical lymphocytes staining pattern with ab46900.
数据表及文件
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Datasheet download
文献 (0)
ab46900 尚未被引用在任何文献中。
