Anti-CD204抗体(ab123946)
Key features and details
- Rabbit polyclonal to CD204
- Suitable for: WB, ICC/IF
- Reacts with: Human
- Isotype: IgG
概述
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产品名称
Anti-CD204抗体
参阅全部 CD204 一抗 -
描述
兔多克隆抗体to CD204 -
宿主
Rabbit -
经测试应用
适用于: WB, ICC/IFmore details -
种属反应性
与反应: Human -
免疫原
Synthetic peptide corresponding to Human CD204 aa 300-400.
Database link: P21757 -
常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Store at 4°C (up to 6 months). Store at -20°C. -
存储溶液
Preservative: 0.1% Sodium azide
Constituents: 69% PBS, 30% Glycerol -
Concentration information loading... -
纯度
Protein A purified -
克隆
多克隆 -
同种型
IgG -
研究领域
相关产品
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Compatible Secondaries
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Isotype control
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab123946于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度；实际最佳的稀释度/浓度应由使用者检定。
| 应用 | Ab评论 | 说明 |
|---|---|---|
| WB |
Use a concentration of 0.5 µg/ml. Detects a band of approximately 50 kDa (predicted molecular weight: 50 kDa).
|
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| ICC/IF |
1/50 - 1/200.
|
| 说明 |
|---|
|
WB
Use a concentration of 0.5 µg/ml. Detects a band of approximately 50 kDa (predicted molecular weight: 50 kDa). |
|
ICC/IF
1/50 - 1/200. |
靶标
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功能
Membrane glycoproteins implicated in the pathologic deposition of cholesterol in arterial walls during atherogenesis. Two types of receptor subunits exist. These receptors mediate the endocytosis of a diverse group of macromolecules, including modified low density lipoproteins (LDL). Isoform III does not internalize actetylated LDL. -
组织特异性
Isoform I, isoform II and isoform III are expressed in monocyte-derived macrophages. -
序列相似性
Contains 1 collagen-like domain.
Contains 1 SRCR domain. -
细胞定位
Membrane. - Information by UniProt
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数据库链接
- Entrez Gene: 4481 Human
- Omim: 153622 Human
- SwissProt: P21757 Human
- Unigene: 147635 Human
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别名
- CD204 antibody
- CD204 antigen antibody
- CD24 antibody
see all
图片
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Western blot - Anti-CD204 antibody (ab123946)Anti-CD204 antibody (ab123946) at 0.5 µg/ml + Human liver lysate
Predicted band size: 50 kDa
Observed band size: 50 kDa -
Immunocytochemistry/ Immunofluorescence - Anti-CD204 antibody (ab123946)ab123946, at a 1/50 dilution, staining CD204 (green) in Hela cells by Immunofluorescence. Nuclei (blue) are counterstained using Hoechst 33258.
实验方案
数据表及文件
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SDS download
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Datasheet download
文献 (17)
ab123946 被引用在 17 文献中.
- Wang Y et al. A small-molecule inhibitor of Keap1-Nrf2 interaction attenuates sepsis by selectively augmenting the antibacterial defence of macrophages at infection sites. EBioMedicine 90:104480 (2023). PubMed: 36863256
- Campos-Sánchez JC et al. Implication of mucus-secreting cells, acidophilic granulocytes and monocytes/macrophages in the resolution of skin inflammation caused by subcutaneous injection of λ/κ-carrageenin to gilthead seabream (Sparus aurata) specimens. J Fish Dis 45:19-33 (2022). PubMed: 34549432
- Tian Y et al. Activation of RARα Receptor Attenuates Neuroinflammation After SAH via Promoting M1-to-M2 Phenotypic Polarization of Microglia and Regulating Mafb/Msr1/PI3K-Akt/NF-κB Pathway. Front Immunol 13:839796 (2022). PubMed: 35237277
- Deng L et al. Tumor-Linked Macrophages Promote HCC Development by Mediating the CCAT1/Let-7b/HMGA2 Signaling Pathway. Onco Targets Ther 13:12829-12843 (2020). PubMed: 33363387
- Xia X et al. Deubiquitination of CD36 by UCHL1 promotes foam cell formation. Cell Death Dis 11:636 (2020). PubMed: 32801299