重组Anti-CD2抗体[EPR3693] (ab119993)
![Western blot - Anti-CD2 antibody [EPR3693] (ab119993)](https://www.abcam.cn/ps/products/119/ab119993/Images/ab119993-133592-anti-cd2-antibody-epr3693-western-blot.jpg "Western blot - Anti-CD2 antibody [EPR3693] (ab119993)")
Key features and details
- Produced recombinantly (animal-free) for high batch-to-batch consistency and long term security of supply
- Rabbit monoclonal [EPR3693] to CD2
- Suitable for: WB
- Reacts with: Human
Related conjugates and formulations
概述
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产品名称
Anti-CD2抗体[EPR3693]
参阅全部 CD2 一抗 -
描述
兔单克隆抗体[EPR3693] to CD2 -
宿主
Rabbit -
经测试应用
适用于: WBmore details
不适用于: Flow Cyt,IHC-P or IP -
种属反应性
与反应: Human -
免疫原
Synthetic peptide. This information is proprietary to Abcam and/or its suppliers.
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阳性对照
- PBMC and Jurkat cell lysate
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常规说明
This product is a recombinant monoclonal antibody, which offers several advantages including:
- - High batch-to-batch consistency and reproducibility
- - Improved sensitivity and specificity
- - Long-term security of supply
- - Animal-free production
Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb® patents.
Mouse, Rat: We have preliminary internal testing data to indicate this antibody may not react with these species. Please contact us for more information.
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Store at -20°C. Stable for 12 months at -20°C. -
存储溶液
pH: 7.20
Preservative: 0.01% Sodium azide
Constituents: 50% Glycerol (glycerin, glycerine), 0.05% BSA -
Concentration information loading... -
纯度
Protein A purified -
克隆
单克隆 -
克隆编号
EPR3693 -
同种型
IgG -
研究领域
相关产品
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Alternative Versions
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Isotype control
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Positive Controls
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Recombinant Protein
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab119993于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度；实际最佳的稀释度/浓度应由使用者检定。
| 应用 | Ab评论 | 说明 |
|---|---|---|
| WB |
1/1000 - 1/2000. Detects a band of approximately 50 kDa (predicted molecular weight: 39 kDa).
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| 说明 |
|---|
|
WB
1/1000 - 1/2000. Detects a band of approximately 50 kDa (predicted molecular weight: 39 kDa). |
应用说明
Is unsuitable for Flow Cyt,IHC-P or IP.
靶标
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功能
CD2 interacts with lymphocyte function-associated antigen (LFA-3) and CD48/BCM1 to mediate adhesion between T-cells and other cell types. CD2 is implicated in the triggering of T-cells, the cytoplasmic domain is implicated in the signaling function. -
序列相似性
Contains 1 Ig-like C2-type (immunoglobulin-like) domain.
Contains 1 Ig-like V-type (immunoglobulin-like) domain. -
细胞定位
Membrane. - Information by UniProt
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数据库链接
- Entrez Gene: 914 Human
- Omim: 186990 Human
- SwissProt: P06729 Human
- Unigene: 523500 Human
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别名
- CD 2 antibody
- CD2 antibody
- CD2 antigen (p50), sheep red blood cell receptor antibody
see all
图片
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Western blot - Anti-CD2 antibody [EPR3693] (ab119993)All lanes : Anti-CD2 antibody [EPR3693] (ab119993) at 1/1000 dilution
Lane 1 : PBMC cell lysate
Lane 2 : Jurkat cell lysate
Lysates/proteins at 10 µg per lane.
Predicted band size: 39 kDa
Observed band size: 50 kDa why is the actual band size different from the predicted? -
![Anti-CD2 antibody [EPR3693] (ab119993)](https://www.abcam.cn/ps/products/119/ab119993/Images/ab119993-2-benefits-of-recombinant-antibodies.png)
Anti-CD2 antibody [EPR3693] (ab119993)
数据表及文件
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SDS download
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Datasheet download
文献 (2)
ab119993 被引用在 2 文献中.
- Foster CT et al. Mutual dependence of the MRTF-SRF and YAP-TEAD pathways in cancer-associated fibroblasts is indirect and mediated by cytoskeletal dynamics. Genes Dev 31:2361-2375 (2017). PubMed: 29317486
- Boissard F et al. Nurse-like cells promote CLL survival through LFA-3/CD2 interactions. Oncotarget 8:52225-52236 (2017). Flow Cyt, ICC/IF . PubMed: 28881725