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Anti-CD1c抗体[M241] (ab18216)

Submit a review Q&A (1)References (3)

Key features and details

  • Mouse monoclonal [M241] to CD1c
  • Suitable for: IP, IHC, RID
  • Reacts with: Human
  • Isotype: IgG1

概述

  • 产品名称

    Anti-CD1c抗体[M241]
    参阅全部 CD1c 一抗

  • 描述

    小鼠单克隆抗体[M241] to CD1c

  • 宿主

    Mouse

  • 经测试应用

    适用于: IP, IHC, RIDmore details

  • 种属反应性

    与反应: Human

  • 免疫原

    Tissue, cells or virus corresponding to Human CD1c. MOLT 4 cell line.

  • 常规说明

    The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.

    If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As

性能

  • 形式

    Liquid

  • 存放说明

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.

  • 存储溶液

    Preservative: 0.02% Sodium azide
    Constituent: 99.98% PBS
  • Concentration information loading...

  • 纯度

    Protein A/G purified

  • 克隆

    单克隆

  • 克隆编号

    M241

  • 同种型

    IgG1

  • 研究领域

应用

The Abpromise guarantee

Abpromise™承诺保证使用ab18216于以下的经测试应用

“应用说明”部分 下显示的仅为推荐的起始稀释度；实际最佳的稀释度/浓度应由使用者检定。

应用 Ab评论 说明
IP
Use at an assay dependent concentration.
IHC
Use at an assay dependent concentration.
RID
Use at an assay dependent concentration.
说明
IP
Use at an assay dependent concentration.
IHC
Use at an assay dependent concentration.
RID
Use at an assay dependent concentration.

靶标

  • 功能

    Antigen-presenting protein that binds self and non-self lipid and glycolipid antigens and presents them to T-cell receptors on natural killer T-cells.

  • 组织特异性

    Expressed on cortical thymocytes, on certain T-cell leukemias, and in various other tissues.

  • 序列相似性

    Contains 1 Ig-like (immunoglobulin-like) domain.

  • 细胞定位

    Cell membrane. Endosome membrane. Subject to intracellular trafficking between the cell membrane and endosomes.
  • Information by UniProt

  • 数据库链接

    • 别名

      • BDCA1 antibody
      • CD1 antibody
      • CD1A antibody
      • CD1c antibody
      • CD1c antigen antibody
      • CD1C antigen c polypeptide antibody
      • CD1c molecule antibody
      • CD1C_HUMAN antibody
      • Cortical thymocyte antigen CD1C antibody
      • Differentiation antigen CD1 alpha 3 antibody
      • R7 antibody
      • T cell surface glycoprotein CD1c antibody
      • T-cell surface glycoprotein CD1c antibody
      see all

    文献 (3)

    发表研究结果有使用 ab18216？请让我们知道，以便我们可以引用本数据表中的参考文章。

    ab18216 被引用在 3 文献中.

    • Duchalais E  et al. Colorectal Cancer Cells Adhere to and Migrate Along the Neurons of the Enteric Nervous System. Cell Mol Gastroenterol Hepatol 5:31-49 (2018). PubMed: 29188232
    • Small TN  et al. Characterization of B cells in severe combined immunodeficiency disease. Hum Immunol 25:181-93 (1989). PubMed: 2670851
    • Knowles RW & Bodmer WF A monoclonal antibody recognizing a human thymus leukemia-like antigen associated with beta 2-microglobulin. Eur J Immunol 12:676-81 (1982). PubMed: 6754387

    客户评价及客户问答

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    Question

    Dear Sir/Madam,

    I'm a user of some primary antibodies which I have purchased from abcam. The antibodies are against CD1a, CD1b and CD1c, product numbers are ab56325, ab96329 and ab18216, respectively. I would like to use these antibodies for a number of applications and I require the sequence of the immunogen to judge whether they'd be appropriate for some of my work. Could you please supply the amino acid sequence of the respective immunogens?

    Best regards,

    Read More
    Answer

    Thank you for your inquiry.

    Please excuse the delay in my answer, I was in contact with the lab that produce these antibodies.

    Unfortunately, I was not told the immunogen for ab56325 and I apologize for any inconvenience this causes to you.

    The immunogen for ab18216 was cells from the MOLT4 cell line and there is no further information if the epitope was mapped available. And therefore we donot not the immunogen sequence.

    I am happy to confirm that the immunogen for ab96329 was a recombinant fragment, corresponding to a region within amino acids 61-258 of Human CD1b (NP_001755).

    I hope this information is helpful. Please donot hesitate to contact me again with any further questions.

    Read More

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