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RabMAb

Anti-CD1b抗体[EP7251] (ab173576)

Submit a review Submit a question References (2)
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-CD1b antibody [EP7251] (ab173576)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-CD1b antibody [EP7251] (ab173576)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-CD1b antibody [EP7251] (ab173576)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-CD1b antibody [EP7251] (ab173576)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-CD1b antibody [EP7251] (ab173576)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-CD1b antibody [EP7251] (ab173576)
  • Immunocytochemistry/ Immunofluorescence - Anti-CD1b antibody [EP7251] (ab173576)
  • Western blot - Anti-CD1b antibody [EP7251] (ab173576)

Key features and details

  • Rabbit monoclonal [EP7251] to CD1b
  • Suitable for: WB, IHC-P, ICC/IF
  • Reacts with: Human
  • Isotype: IgG

Conjugates logo Related conjugates and formulations

Carrier Free

概述

  • 产品名称

    Anti-CD1b抗体[EP7251]
    参阅全部 CD1b 一抗

  • 描述

    兔单克隆抗体[EP7251] to CD1b

  • 宿主

    Rabbit

  • 经测试应用

    适用于: WB, IHC-P, ICC/IFmore details
    不适用于: Flow Cyt or IP

  • 种属反应性

    与反应: Human
    不与反应: Mouse, Rat

  • 免疫原

    Synthetic peptide within Human CD1b aa 50-150 (Cysteine residue). The exact sequence is proprietary.
    Database link: P29016

    Run BLAST with BLAST the sequence with ExPASy Run BLAST with BLAST the sequence with NCBI

  • 阳性对照

    • Fetal thymus and Jurkat lysates, Human spleen tissue, Jurkat cells.

  • 常规说明

    Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb® patents.

    The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.

    If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As

性能

  • 形式

    Liquid

  • 存放说明

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.

  • 存储溶液

    pH: 7.20
    Preservative: 0.01% Sodium azide
    Constituents: 9% PBS, 40% Glycerol (glycerin, glycerine), 0.05% BSA, 50% Tissue culture supernatant
  • Concentration information loading...

  • 纯度

    Tissue culture supernatant

  • 克隆

    单克隆

  • 克隆编号

    EP7251

  • 同种型

    IgG

  • 研究领域

应用

The Abpromise guarantee

Abpromise™承诺保证使用ab173576于以下的经测试应用

“应用说明”部分 下显示的仅为推荐的起始稀释度；实际最佳的稀释度/浓度应由使用者检定。

应用 Ab评论 说明
WB
1/1000 - 1/10000. Predicted molecular weight: 37 kDa.
IHC-P
1/100 - 1/250. Perform heat mediated antigen retrieval before commencing with IHC staining protocol.
ICC/IF
1/50 - 1/100.
说明
WB
1/1000 - 1/10000. Predicted molecular weight: 37 kDa.
IHC-P
1/100 - 1/250. Perform heat mediated antigen retrieval before commencing with IHC staining protocol.
ICC/IF
1/50 - 1/100.
应用说明
Is unsuitable for Flow Cyt or IP.

靶标

  • 功能

    Antigen-presenting protein that binds self and non-self lipid and glycolipid antigens and presents them to T-cell receptors on natural killer T-cells.

  • 组织特异性

    Expressed on cortical thymocytes, on certain T-cell leukemias, and in various other tissues.

  • 序列相似性

    Contains 1 Ig-like (immunoglobulin-like) domain.

  • 细胞定位

    Cell membrane. Endosome membrane. Lysosome membrane. Subject to intracellular trafficking between the cell membrane, endosomes and lysosomes. Localizes to cell surface lipid rafts.
  • Information by UniProt

  • 数据库链接

    • 别名

      • A1 domain antibody
      • CD1 antibody
      • CD1A antibody
      • CD1b antibody
      • CD1b antigen antibody
      • CD1B antigen b polypeptide antibody
      • CD1b molecule antibody
      • CD1B_HUMAN antibody
      • Cortical thymocyte antigen CD1A antibody
      • Cortical thymocyte antigen CD1B antibody
      • Differentiation antigen CD1 alpha 3 antibody
      • hTa1 thymocyte antigen antibody
      • Ly38 antibody
      • Ly38; T cell surface glycoprotein CD1a antibody
      • MGC125990 antibody
      • MGC125991 antibody
      • R1 antibody
      • T-cell surface glycoprotein CD1b antibody
      • T6/Leu6 antibody
      • Thymocite antigen CD1B antibody
      see all

    图片

    • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-CD1b antibody [EP7251] (ab173576)
      Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-CD1b antibody [EP7251] (ab173576)

      Immunohistochemical analysis of paraffin-embedded Human spleen tissue labeling CD1b with ab173576 at 1/100 dilution

      Perform heat mediated antigen retrieval before commencing with IHC staining protocol.

    • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-CD1b antibody [EP7251] (ab173576)
      Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-CD1b antibody [EP7251] (ab173576)

      ab173576 showing +ve staining in Human normal thymus tissue.

      Perform heat mediated antigen retrieval before commencing with IHC staining protocol.

    • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-CD1b antibody [EP7251] (ab173576)
      Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-CD1b antibody [EP7251] (ab173576)

      ab173576 showing +ve staining in Human normal tonsil tissue.

      Perform heat mediated antigen retrieval before commencing with IHC staining protocol.

    • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-CD1b antibody [EP7251] (ab173576)
      Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-CD1b antibody [EP7251] (ab173576)

      ab173576 showing -ve staining in Human normal pancreas tissue.

      Perform heat mediated antigen retrieval before commencing with IHC staining protocol.

    • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-CD1b antibody [EP7251] (ab173576)
      Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-CD1b antibody [EP7251] (ab173576)

      ab173576 showing -ve staining in Human skeletal muscle tissue.

      Perform heat mediated antigen retrieval before commencing with IHC staining protocol.

    • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-CD1b antibody [EP7251] (ab173576)
      Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-CD1b antibody [EP7251] (ab173576)

      ab173576 showing -ve staining in Human endometrial adenocarcinoma tissue.

      Perform heat mediated antigen retrieval before commencing with IHC staining protocol.

    • Immunocytochemistry/ Immunofluorescence - Anti-CD1b antibody [EP7251] (ab173576)
      Immunocytochemistry/ Immunofluorescence - Anti-CD1b antibody [EP7251] (ab173576)

      Immunofluorescent staining of Jurkat cells labeling CD1b with ab173576 at 1/50 dilution

    • Western blot - Anti-CD1b antibody [EP7251] (ab173576)
      Western blot - Anti-CD1b antibody [EP7251] (ab173576)
      All lanes : Anti-CD1b antibody [EP7251] (ab173576) at 1/1000 dilution

      Lane 1 : Human fetal thymus lysate
      Lane 2 : Jurkat lysate

      Lysates/proteins at 10 µg per lane.

      Predicted band size: 37 kDa

    文献 (2)

    发表研究结果有使用 ab173576？请让我们知道，以便我们可以引用本数据表中的参考文章。

    ab173576 被引用在 2 文献中.

    • Li Z  et al. CD1B is a Potential Prognostic Biomarker Associated with Tumor Mutation Burden and Promotes Antitumor Immunity in Lung Adenocarcinoma. Int J Gen Med 15:3809-3826 (2022). PubMed: 35418778
    • Li C  et al. Comprehensive Profiling Reveals Distinct Microenvironment and Metabolism Characterization of Lung Adenocarcinoma. Front Genet 12:619821 (2021). PubMed: 34122500

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