Anti-CD1a抗体[NA1/34-HLK] (ab24055)
Key features and details
- Mouse monoclonal [NA1/34-HLK] to CD1a
- Suitable for: Flow Cyt
- Reacts with: Dog, Human, Monkey
- Isotype: IgG2a
Related conjugates and formulations
概述
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产品名称
Anti-CD1a抗体[NA1/34-HLK]
参阅全部 CD1a 一抗 -
描述
小鼠单克隆抗体[NA1/34-HLK] to CD1a -
宿主
Mouse -
经测试应用
适用于: Flow Cytmore details -
种属反应性
与反应: Dog, Human, Monkey -
免疫原
Tissue, cells or virus corresponding to Human CD1a. Thymocytes (Human).
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常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. -
存储溶液
pH: 7.40
Preservative: 0.09% Sodium azide
Constituents: PBS, 1% BSA -
Concentration information loading... -
纯度
Ion Exchange Chromatography -
纯化说明
Purified IgG prepared by ion exchange chromatography -
克隆
单克隆 -
克隆编号
NA1/34-HLK -
骨髓瘤
NS1/1-Ag4-1 -
同种型
IgG2a -
研究领域
相关产品
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Alternative Versions
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Compatible Secondaries
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Isotype control
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Recombinant Protein
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab24055于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度；实际最佳的稀释度/浓度应由使用者检定。
| 应用 | Ab评论 | 说明 |
|---|---|---|
| Flow Cyt |
Use at an assay dependent concentration.
Use 10 ul of this concentration to label 10^6 cells in 100ul. ab170191 - Mouse monoclonal IgG2a, is suitable for use as an isotype control with this antibody. |
| 说明 |
|---|
|
Flow Cyt
Use at an assay dependent concentration. Use 10 ul of this concentration to label 10^6 cells in 100ul. ab170191 - Mouse monoclonal IgG2a, is suitable for use as an isotype control with this antibody. |
靶标
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功能
Antigen-presenting protein that binds self and non-self lipid and glycolipid antigens and presents them to T-cell receptors on natural killer T-cells. -
组织特异性
Expressed on cortical thymocytes, epidermal Langerhans cells, dendritic cells, on certain T-cell leukemias, and in various other tissues. -
序列相似性
Contains 1 Ig-like (immunoglobulin-like) domain. -
细胞定位
Cell membrane. Endosome membrane. Subject to intracellular trafficking between the cell membrane and endosomes. Localizes to cell surface lipid rafts. - Information by UniProt
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数据库链接
- Entrez Gene: 909 Human
- Omim: 188370 Human
- SwissProt: P06126 Human
- Unigene: 1309 Human
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别名
- CD 1a antibody
- CD1 antibody
- CD1a antibody
see all
数据表及文件
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SDS download
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Datasheet download
文献 (6)
ab24055 被引用在 6 文献中.
- Qeska V et al. Canine distemper virus infection leads to an inhibitory phenotype of monocyte-derived dendritic cells in vitro with reduced expression of co-stimulatory molecules and increased interleukin-10 transcription. PLoS One 9:e96121 (2014). Flow Cyt . PubMed: 24769532
- West JA et al. Polyclonal T-cells express CD1a in Langerhans cell histiocytosis (LCH) lesions. PLoS One 9:e109586 (2014). ICC ; Human . PubMed: 25343480
- Yoshino N et al. Upgrading of flow cytometric analysis for absolute counts, cytokines and other antigenic molecules of cynomolgus monkeys (Macaca fascicularis) by using anti-human cross-reactive antibodies. Exp Anim 49:97-110 (2000). PubMed: 10889948
- Galkowska H et al. Reactivity of antibodies directed against human antigens with surface markers on canine leukocytes. Vet Immunol Immunopathol 53:329-34 (1996). PubMed: 8969052
- Burrone OR & Milstein C Control of HLA-A,B,C synthesis and expression in interferon-treated cells. EMBO J 1:345-9 (1982). PubMed: 6765173
- McMichael AJ et al. A human thymocyte antigen defined by a hybrid myeloma monoclonal antibody. Eur J Immunol 9:205-10 (1979). PubMed: 376318