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AB7495

Anti-CD15抗体[MMA]，prediluted

Anti-CD15 antibody [MMA], prediluted

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(1 Publication)

Mouse Monoclonal CD15 antibody. Suitable for IHC-P and reacts with Human samples. Cited in 1 publication. Immunogen corresponding to Cell preparation containing U937 protein.
1 Images
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-CD15 antibody [MMA], prediluted (AB7495)
  • IHC-P

Unknown

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-CD15 antibody [MMA], prediluted (AB7495)

Immunohistochemistry (Formalin fixed paraffin-embedded sections) analysis of human tonsil tissue labelling CD15 with ab7495.

不同偶联物与剂型 (1)

关键信息

宿主种属

Mouse

克隆

Monoclonal

克隆号

MMA

亚型

IgM

轻链类型

kappa

不含载体蛋白

No

反应种属

Human

应用

IHC-P

applications

免疫原

The exact immunogen used to generate this antibody is proprietary information.

特异性

This antibody reacts with a 220 kD protein.

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替代产品

Primary Antibodies

AB218403

Anti-CD15 antibody [FUT4/1478R]

Recombinant

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-CD15 antibody [FUT4/1478R] (AB218403)

  • 0
  • 0
Primary Antibodies

AB172729

Anti-CD15 antibody [EPR9521]

RabMAb|Recombinant

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-CD15 antibody [EPR9521] (AB172729)

  • 0
  • 0
Primary Antibodies

AB135377

Anti-CD15 antibody [SP159]

20ul selling size|BOND RX™ Validated|Advanced Validation|RabMAb|Recombinant

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-CD15 antibody [SP159] (AB135377)

  • 5
  • 1
Primary Antibodies

AB240092

Anti-CD15 antibody [SP159] - BSA and Azide free

BOND RX™ Validated|Advanced Validation|RabMAb|Recombinant

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-CD15 antibody [SP159] - BSA and Azide free (AB240092)

  • 5
  • 1
Primary Antibodies

AB240171

Anti-CD15 antibody [EPR9521] - BSA and Azide free

RabMAb|Recombinant

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-CD15 antibody [EPR9521] - BSA and Azide free (AB240171)

  • 0
  • 0

搭配使用产品

Primary Antibodies

AB64088

Anti-CD20 antibody [SP32]

BOND RX™ Validated|20ul selling size|RabMAb|Advanced Validation|Recombinant|KO Validated

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-CD20 antibody [SP32] (AB64088)

  • 5
  • 13
Primary Antibodies

AB81289

Anti-CD34 antibody [EP373Y]

BOND RX™ Validated|RabMAb|Recombinant|20ul selling size

Flow Cytometry (Intracellular) - Anti-CD34 antibody [EP373Y] (AB81289)

  • 4
  • 56
Primary Antibodies

AB227640

Anti-CD10 antibody [SP67]

20ul selling size|BOND RX™ Validated|RabMAb|Recombinant

Flow Cytometry - Anti-CD10 antibody [SP67] (AB227640)

  • 5
  • 1
Primary Antibodies

AB130405

Anti-Syndecan-1 antibody [SP152]

20ul selling size|RabMAb|Recombinant

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Syndecan-1 antibody [SP152] (AB130405)

  • 0
  • 0
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反应性数据

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "IHCP" : {"fullname" : "Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)", "shortname":"IHC-P"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "IHCP-species-checked": "testedAndGuaranteed", "IHCP-species-dilution-info": "", "IHCP-species-notes": "<p></p>" } } }
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性能和储存信息

形式
Liquid
纯化工艺
Affinity purification Protein A
存储溶液
pH: 7.3 - 7.5 Constituents: PBS
运输条件
Blue Ice
推荐的短期储存时间
1-2 weeks
推荐的短期储存条件
+4°C
推荐的长期储存条件
-20°C
储存信息
Avoid freeze / thaw cycle
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补充信息

This supplementary information is collated from multiple sources and compiled automatically.

CD15 also known as Lewis x or 3-fucosyl-N-acetyllactosamine is a carbohydrate antigen with a molecular mass typically not individually defined due to its nature as a glycan. CD15 is expressed on the surface of many human cells including neutrophils and various epithelial cells. It is commonly associated with granulocytes and is used as a cell surface marker. The presence of CD15 can be identified using CD15 antibodies through techniques such as CD15 flow cytometry and CD15 APC labeling.
Biological function summary

CD15 is important in cell-cell interaction mechanisms. It plays a role in mediating adhesion processes particularly in immune responses where it aids neutrophils in adhering to vascular endothelium and transmigrating to sites of infection or inflammation. As a glycoconjugate CD15 forms part of a larger glycoprotein complex on the cell surface interacting with other proteins to facilitate cellular responses and movement.

Pathways

CD15's function as an adhesion molecule ties into key cellular processes such as the selectin pathway. In this pathway it interacts with proteins like E-selectin and L-selectin contributing to leukocyte rolling and extravasation during the immune response. Additionally CD15 is implicated in the signaling pathways that mediate inflammatory responses where its role in neutrophil dynamics is important.

CD15 has notable implications in Hodgkin's lymphoma and certain myeloid leukemias. It is frequently used as a diagnostic marker in these conditions where its overexpression or abnormal expression patterns may signify disease presence or progression. CD15's interaction with other proteins such as CD30 in Hodgkin's lymphoma highlights its utility in understanding the pathological mechanisms and potential therapeutic targets of these disorders.
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产品实验方案

For this product, it's our understanding that no specific protocols are required. You can visit:
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靶点信息

See full target information CD15
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文献 (1)

Recent publications for all applications. Explore the full list and refine your search

Cancer cell 18:655-68 PubMed21156287

2010

TGF-β Receptor Inhibitors Target the CD44(high)/Id1(high) Glioma-Initiating Cell Population in Human Glioblastoma.

Applications

IF

Species

Human

Judit Anido,Andrea Sáez-Borderías,Alba Gonzàlez-Juncà,Laura Rodón,Gerard Folch,Maria A Carmona,Rosa M Prieto-Sánchez,Ignasi Barba,Elena Martínez-Sáez,Ludmila Prudkin,Isabel Cuartas,Carolina Raventós,Francisco Martínez-Ricarte,M Antonia Poca,David García-Dorado,Michael M Lahn,Jonathan M Yingling,Jordi Rodón,Juan Sahuquillo,José Baselga,Joan Seoane
View all publications
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Abcam Product Promise

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