Anti-CD14抗体[UCHM1] (ab6623)
![Flow Cytometry - Anti-CD14 antibody [UCHM1] (ab6623)](https://www.abcam.cn/ps/products/6/ab6623/Images/ab6623_1.jpg "Flow Cytometry - Anti-CD14 antibody [UCHM1] (ab6623)")
Key features and details
- Mouse monoclonal [UCHM1] to CD14
- Suitable for: Flow Cyt
- Reacts with: Human
- Isotype: IgG2a
概述
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产品名称
Anti-CD14抗体[UCHM1]
参阅全部 CD14 一抗 -
描述
小鼠单克隆抗体[UCHM1] to CD14 -
宿主
Mouse -
特异性
ab6623 recognises a monocyte surface antigen of 55 kDa found chiefly on monocytes. UCHM1 was clustered at the Third International Workshop and Conference on Human Leucocyte Differentiation Antigens. Oxford 1986, as CDw14, group A. In tonsil tissue sections UCHM1 gives positive staining reactions with monocytic cells, the interfollicular tissue macrophages seen under the capsule, and dendritic reticulum cells. Skin Langerhans cells are always negative. UCHM1 also reacts with Kupffer cells and sinus lining cells on the liver. -
经测试应用
适用于: Flow Cytmore details
不适用于: IHC-P -
种属反应性
与反应: Human -
免疫原
Tissue, cells or virus corresponding to Human CD14. Human Thymocytes followed by peripheral blood mononuclear cells
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阳性对照
- Tonsil.
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常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles. -
存储溶液
pH: 7.60
Preservative: 0.09% Sodium azide -
Concentration information loading... -
纯度
Protein G purified -
纯化说明
Purified IgG prepared by affinity chromatography on Protein G from tissue culture supernatant. -
克隆
单克隆 -
克隆编号
UCHM1 -
骨髓瘤
NS1/1-Ag4-1 -
同种型
IgG2a -
研究领域
相关产品
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Compatible Secondaries
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Isotype control
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Recombinant Protein
应用
| 应用 | Ab评论 | 说明 |
|---|---|---|
| Flow Cyt |
Use at an assay dependent concentration.
ab170191 - Mouse monoclonal IgG2a, is suitable for use as an isotype control with this antibody. |
| 说明 |
|---|
|
Flow Cyt
Use at an assay dependent concentration. ab170191 - Mouse monoclonal IgG2a, is suitable for use as an isotype control with this antibody. |
靶标
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功能
Cooperates with MD-2 and TLR4 to mediate the innate immune response to bacterial lipopolysaccharide (LPS). Acts via MyD88, TIRAP and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Up-regulates cell surface molecules, including adhesion molecules. -
组织特异性
Expressed strongly on the surface of monocytes and weakly on the surface of granulocytes; also expressed by most tissue macrophages. -
序列相似性
Contains 11 LRR (leucine-rich) repeats. -
翻译后修饰
N- and O- glycosylated. O-glycosylated with a core 1 or possibly core 8 glycan. -
细胞定位
Cell membrane. - Information by UniProt
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数据库链接
- Entrez Gene: 929 Human
- Omim: 158120 Human
- SwissProt: P08571 Human
- Unigene: 163867 Human
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别名
- CD 14 antibody
- CD_antigen=CD14 antibody
- CD14 antibody
see all
图片
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Flow Cytometry - Anti-CD14 antibody [UCHM1] (ab6623)ab6623 staining of human peripheral blood monocytes, visualised with rabbit anti-mouse IgG: FITC.
实验方案
数据表及文件
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SDS download
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Datasheet download
文献 (0)
ab6623 尚未被引用在任何文献中。