Anti-CCR1抗体(ab19013)
Key features and details
- Rabbit polyclonal to CCR1
- Suitable for: WB
- Reacts with: Human
- Isotype: IgG
概述
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产品名称
Anti-CCR1抗体
参阅全部 CCR1 一抗 -
描述
兔多克隆抗体to CCR1 -
宿主
Rabbit -
经测试应用
适用于: WBmore details -
种属反应性
与反应: Human -
免疫原
Synthetic peptide corresponding to Human CCR1. Surrounding amino acid 341.
Database link: P32246 -
阳性对照
- WB: Jurkat cell lysate.
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常规说明
This product is manufactured by BioVision, an Abcam company and was previously called 3414 CCR1 Antibody. 3414-100 is the same size as the 100 µg size of ab19013.
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles. -
存储溶液
Preservative: 0.01% Thimerosal (merthiolate)
Constituents: PBS, 30% Glycerol (glycerin, glycerine), 0.5% BSA -
Concentration information loading... -
纯度
Affinity purified -
克隆
多克隆 -
同种型
IgG -
研究领域
相关产品
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Compatible Secondaries
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Isotype control
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab19013于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度；实际最佳的稀释度/浓度应由使用者检定。
| 应用 | Ab评论 | 说明 |
|---|---|---|
| WB |
Use a concentration of 0.5 - 4 µg/ml. Predicted molecular weight: 43 kDa.
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| 说明 |
|---|
|
WB
Use a concentration of 0.5 - 4 µg/ml. Predicted molecular weight: 43 kDa. |
靶标
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功能
Receptor for a C-C type chemokine. Binds to MIP-1-alpha, MIP-1-delta, RANTES, and MCP-3 and, less efficiently, to MIP-1-beta or MCP-1 and subsequently transduces a signal by increasing the intracellular calcium ions level. Responsible for affecting stem cell proliferation. -
组织特异性
Widely expressed in different hematopoietic cells. -
序列相似性
Belongs to the G-protein coupled receptor 1 family. -
细胞定位
Cell membrane. - Information by UniProt
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数据库链接
- Entrez Gene: 1230 Human
- Omim: 601159 Human
- SwissProt: P32246 Human
- Unigene: 301921 Human
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别名
- C C chemokine receptor type 1 antibody
- C C CKR 1 antibody
- C-C chemokine receptor type 1 antibody
see all
图片
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Western blot - Anti-CCR1 antibody (ab19013)All lanes : Anti-CCR1 antibody (ab19013)
All lanes : Jurkat cell lysate
Predicted band size: 43 kDa
数据表及文件
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SDS download
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Datasheet download
文献 (7)
ab19013 被引用在 7 文献中.
- Wu C et al. Mapk7 deletion in chondrocytes causes vertebral defects by reducing MEF2C/PTEN/AKT signaling. Genes Dis 11:964-977 (2024). IHC-Fr ; Mouse . PubMed: 37692479
- Meng J et al. CCL23 suppresses liver cancer progression through the CCR1/AKT/ESR1 feedback loop. Cancer Sci 112:3099-3110 (2021). PubMed: 34050704
- Liang Z et al. Curcumin inhibits the migration of osteoclast precursors and osteoclastogenesis by repressing CCL3 production. BMC Complement Med Ther 20:234 (2020). PubMed: 32703287
- Pincha N et al. PAI1 mediates fibroblast-mast cell interactions in skin fibrosis. J Clin Invest 128:1807-1819 (2018). PubMed: 29584619
- Zhang Y et al. Effect of Tetramethylpyrazine on Atherosclerosis and SCAP/SREBP-1c Signaling Pathway in ApoE(-/-) Mice Fed with a High-Fat Diet. Evid Based Complement Alternat Med 2017:3121989 (2017). PubMed: 28491104
- Hyldahl RD et al. Satellite cell activity is differentially affected by contraction mode in human muscle following a work-matched bout of exercise. Front Physiol 5:485 (2014). IHC . PubMed: 25566087
- Barron DA et al. TGF-ß1 Induces an Age-Dependent Inflammation of Nerve Ganglia and Fibroplasia in the Prostate Gland Stroma of a Novel Transgenic Mouse. PLoS One 5:e13751 (2010). IHC . PubMed: 21060787