Anti-CCL4/MIP-1 beta抗体(ab106548)
Key features and details
- Rabbit polyclonal to CCL4/MIP-1 beta
- Suitable for: WB
- Reacts with: Pig
- Isotype: IgG
概述
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产品名称
Anti-CCL4/MIP-1 beta抗体
参阅全部 CCL4/MIP-1 beta 一抗 -
描述
兔多克隆抗体to CCL4/MIP-1 beta -
宿主
Rabbit -
特异性
This antibody is specific for swine CCL4 protein. A BLAST analysis was used to suggest cross-reactivity with CCL4 from swine sources based on 100% homology with the immunizing sequence. Partial reactivity is expected against horse and panda CCL4 based on 90% homology. Cross-reactivity with CCL4 from other sources has not been determined. The swine CCL4 sequence is also 86% homologous to swine CCL3L1.
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经测试应用
适用于: WBmore details -
种属反应性
与反应: Pig
预测可用于: Rat, Rabbit, Horse, Cow, Cat, Dog, Chimpanzee, Macaque monkey, Opossum
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免疫原
Recombinant full length protein corresponding to Pig CCL4/MIP-1 beta aa 1 to the C-terminus. Mature full length chain without signal peptide.
Database link: Q711P4 -
阳性对照
- Recombinant Pig CCL4/MIP-1 beta.
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常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle. -
存储溶液
pH: 7.2
Preservative: 0.01% Sodium azide
Constituents: 0.424% Potassium phosphate solution, 0.88% Sodium chloride -
Concentration information loading... -
纯度
Protein A purified -
纯化说明
This product was Protein-A purified from monospecific antiserum by chromatography. -
克隆
多克隆 -
同种型
IgG -
研究领域
相关产品
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Compatible Secondaries
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Isotype control
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab106548于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度；实际最佳的稀释度/浓度应由使用者检定。
| 应用 | Ab评论 | 说明 |
|---|---|---|
| WB |
1/500. Predicted molecular weight: 10 kDa.
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| 说明 |
|---|
|
WB
1/500. Predicted molecular weight: 10 kDa. |
靶标
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功能
Monokine with inflammatory and chemokinetic properties. Binds to CCR5. One of the major HIV-suppressive factors produced by CD8+ T-cells. Recombinant MIP-1-beta induces a dose-dependent inhibition of different strains of HIV-1, HIV-2, and simian immunodeficiency virus (SIV). The processed form MIP-1-beta(3-69) retains the abilities to induce down-modulation of surface expression of the chemokine receptor CCR5 and to inhibit the CCR5-mediated entry of HIV-1 in T-cells. MIP-1-beta(3-69) is also a ligand for CCR1 and CCR2 isoform B. -
序列相似性
Belongs to the intercrine beta (chemokine CC) family. -
翻译后修饰
N-terminal processed form MIP-1-beta(3-69) is produced by proteolytic cleavage after secretion from peripheral blood lymphocytes. -
细胞定位
Secreted. - Information by UniProt
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数据库链接
- Entrez Gene: 414347 Cow
- Entrez Gene: 448786 Dog
- Entrez Gene: 100057859 Horse
- Entrez Gene: 116637 Rat
- SwissProt: Q17QA1 Cow
- SwissProt: Q68AZ0 Dog
- SwissProt: P50230 Rat
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别名
- MIP 1 beta antibody
- Secreted protein G 26 antibody
- ACT 2 antibody
see all
图片
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Western blot - Anti-CCL4/MIP-1 beta antibody (ab106548)Anti-CCL4/MIP-1 beta antibody (ab106548) at 4 µg/ml + Recombinant Pig CCL4/MIP-1 beta.
Secondary
IRDye800™ Conjugated Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 10 kDa
数据表及文件
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SDS download
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Datasheet download
文献 (0)
ab106548 尚未被引用在任何文献中。