AB126514

Anti-CCDC81抗体

Name: CCDC81抗体 (ab126514)| Abcam中文官网
Brand: Abcam Limited
SKU: AB126514
Price: 5757 CNY
Availability: InStock

Anti-CCDC81 antibody

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(1 Publication)

Rabbit Polyclonal CCDC81 antibody. Suitable for IHC-P, WB and reacts with Human samples. Cited in 1 publication. Immunogen corresponding to Recombinant Fragment Protein within Human CCDC81 aa 350-500.

查看别名

Coiled-coil domain-containing protein 81, CCDC81

2 Images

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-CCDC81 antibody (AB126514)

IHC-P

Unknown

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-CCDC81 antibody (AB126514)

ab126514, at 1/200 dilution, staining CCDC81 in paraffin-embedded Human kidney tissue by Immunohistochemistry

Unknown

Western blot - Anti-CCDC81 antibody (AB126514)

All lanes:

Western blot - Anti-CCDC81 antibody (ab126514) at 1/250 dilution

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RT-4 cell lysate

Lane 2:

U-251 MG cell lysate

Lane 3:

Human plasma lysate

Lane 4:

Human liver lysate

Lane 5:

Human tonsil lysate

Predicted band size: 76 kDa

false

关键信息

宿主种属

Rabbit

克隆

Polyclonal

亚型

IgG

不含载体蛋白

反应种属

Human

应用

IHC-P, WB

applications

免疫原

Recombinant Fragment Protein within Human CCDC81 aa 350-500. The exact immunogen used to generate this antibody is proprietary information.

Q6ZN84

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反应性数据

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "IHCP" : {"fullname" : "Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)", "shortname":"IHC-P"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "IHCP-species-checked": "testedAndGuaranteed", "IHCP-species-dilution-info": "1/200 - 1/500", "IHCP-species-notes": "<p></p> Perform heat-mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.", "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "1/250 - 1/500", "WB-species-notes": "<p></p>" } } }

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性能和储存信息

形式

Liquid

纯化工艺

Affinity purification Immunogen

存储溶液

pH: 7.2 Preservative: 0.02% Sodium azide Constituents: PBS, 40% Glycerol (glycerin, glycerine)

运输条件

Blue Ice

分装信息

Upon delivery aliquot

储存信息

Avoid freeze / thaw cycle

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补充信息

This supplementary information is collated from multiple sources and compiled automatically.

CCDC81 also known as Coiled-Coil Domain Containing 81 is a protein with a mass of approximately 78 kDa. The protein functions in mechanical support and structural organization within cells. It contains coiled-coil domains which facilitate protein-protein interactions. CCDC81 expresses in various tissues including the brain and heart. The expression pattern suggests its involvement in structural cellular roles relevant to specific tissues.

Biological function summary

In cellular mechanics and organization CCDC81 participates in structural integrity and intracellular transport processes. The coiled-coil domains allow CCDC81 to interact with other cytoskeletal components functioning partly as a linker or scaffold. While the protein does not belong to a well-characterized complex it cooperates with cytoskeletal proteins to maintain cell structure.

Pathways

CCDC81 contributes to cytoskeletal and intracellular transport pathways. It interacts with pathways that manage cellular architecture and transport of vesicles and organelles. In these pathways CCDC81 indirectly associates with proteins like actin and microtubule-associated proteins which are important for structural and transport functions within cells.

The variation or dysregulation of CCDC81 links to neural-related diseases and cardiac disorders. Changes in CCDC81 may influence structural stability affecting functions in neurons and cardiac tissues. Research indicates that CCDC81 interacts with proteins like myosin in cardiomyocytes and potentially contributes to conditions like cardiomyopathy when mutated or improperly expressed.

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产品实验方案

For this product, it's our understanding that no specific protocols are required. You can visit:

Visit the General protocols
Visit the Troubleshooting

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靶点信息

See full target information CCDC81

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文献 (1)

Recent publications for all applications. Explore the full list and refine your search

Frontiers in immunology 14:1179742 PubMed37622116

2023

Identification of cuproptosis and immune-related gene prognostic signature in lung adenocarcinoma.

Applications

Unspecified application

Species

Unspecified reactive species

Wentao Zhang,Haizeng Qu,Xiaoqing Ma,Liang Li,Yanjun Wei,Ye Wang,Renya Zeng,Yuanliu Nie,Chenggui Zhang,Ke Yin,Fengge Zhou,Zhe Yang

View all publications

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Anti-CCDC81抗体

Anti-CCDC81 antibody

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-CCDC81 antibody (AB126514)

Western blot - Anti-CCDC81 antibody (AB126514)