Anti-C8抗体[056B-373] (ab59140)
Key features and details
- Mouse monoclonal [056B-373] to C8
- Suitable for: ELISA, IHC-Fr, Flow Cyt, WB
- Reacts with: Human
- Isotype: IgG1
概述
-
产品名称
Anti-C8抗体[056B-373] -
描述
小鼠单克隆抗体[056B-373] to C8 -
宿主
Mouse -
经测试应用
适用于: ELISA, IHC-Fr, Flow Cyt, WBmore details -
种属反应性
与反应: Human -
免疫原
Full length native protein (purified) corresponding to Human C8. Purified human C8
-
阳性对照
- Kidney from post streptoccal glomerulonephritis patients.
-
常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
-
形式
Liquid -
存放说明
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle. -
存储溶液
Preservative: 0.1% Sodium azide
Constituent: 99% Borate buffered saline -
Concentration information loading... -
纯度
Protein A purified -
克隆
单克隆 -
克隆编号
056B-373 -
同种型
IgG1 -
研究领域
相关产品
-
Compatible Secondaries
-
Conjugation kits
-
Isotype control
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab59140于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度；实际最佳的稀释度/浓度应由使用者检定。
| 应用 | Ab评论 | 说明 |
|---|---|---|
| ELISA |
Use at an assay dependent concentration.
|
|
| IHC-Fr |
Use at an assay dependent concentration.
|
|
| Flow Cyt |
Use at an assay dependent concentration.
ab170190 - Mouse monoclonal IgG1, is suitable for use as an isotype control with this antibody. |
|
| WB |
Use at an assay dependent concentration.
|
| 说明 |
|---|
|
ELISA
Use at an assay dependent concentration. |
|
IHC-Fr
Use at an assay dependent concentration. |
|
Flow Cyt
Use at an assay dependent concentration. ab170190 - Mouse monoclonal IgG1, is suitable for use as an isotype control with this antibody. |
|
WB
Use at an assay dependent concentration. |
靶标
-
相关性
C8 is synthesised in the liver, monocytes and fibroblasts and is a plasma protein consisting of three non identical polypeptide chains. The alpha-chain (64kDa) and gamma chain (22kDa) are disulphide linked, these associate non-covalently with the beta-chain (64kDa), to form the native C8 molecule with a molecular weight of 151kDa. Normal plasma concentration is 80mg/L. C8 is one of the terminal proteins of the complement pathways. C8 binds to the membrane bound C5b-7, C5b-8 combines with C9 to form the membrane attack complex (MAC). The MAC forms a hydrophilic, protein walled, transmembrane channel, formation of which leads to cell lysis and destruction. -
细胞定位
Secreted -
数据库链接
- Entrez Gene: 731 Human
- Entrez Gene: 732 Human
- Entrez Gene: 733 Human
- Omim: 120930 Human
- Omim: 120950 Human
- Omim: 120960 Human
- SwissProt: P07357 Human
- SwissProt: P07358 Human
see all -
别名
- C8A antibody
- C8B antibody
- C8G antibody
see all
实验方案
数据表及文件
-
SDS download
-
Datasheet download
文献 (0)
ab59140 尚未被引用在任何文献中。