Anti-C5a-R抗体[P12/1] (ab24036)
Key features and details
- Mouse monoclonal [P12/1] to C5a-R
- Suitable for: Flow Cyt, WB, IHC-P, IHC-Fr
- Reacts with: Human, Rhesus monkey
- Isotype: IgG2a
概述
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产品名称
Anti-C5a-R抗体[P12/1]
参阅全部 C5a-R 一抗 -
描述
小鼠单克隆抗体[P12/1] to C5a-R -
宿主
Mouse -
特异性
No P12/1 signal after pre-incubation of HMC-1 cells with C5a, meaning that P12/1 does not displace C5a.
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经测试应用
适用于: Flow Cyt, WB, IHC-P, IHC-Frmore details -
种属反应性
与反应: Human, Rhesus monkey -
免疫原
Synthetic peptide corresponding to Human C5a-R aa 1-31 (N terminal).
Sequence:MNSFNYTTPDYGHYDDKDTLDLNTPVDKTSN
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常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. -
存储溶液
pH: 7.3
Preservative: 0.09% Sodium azide
Constituent: PBS -
Concentration information loading... -
纯度
Affinity purified -
克隆
单克隆 -
克隆编号
P12/1 -
同种型
IgG2a -
研究领域
相关产品
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Compatible Secondaries
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Isotype control
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Recombinant Protein
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab24036于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度；实际最佳的稀释度/浓度应由使用者检定。
| 应用 | Ab评论 | 说明 |
|---|---|---|
| Flow Cyt |
Use a concentration of 1 mg/ml.
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| WB |
Use a concentration of 1 mg/ml. Predicted molecular weight: 39 kDa.
|
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| IHC-P |
Use a concentration of 1 mg/ml.
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| IHC-Fr |
Use a concentration of 1 mg/ml.
|
| 说明 |
|---|
|
Flow Cyt
Use a concentration of 1 mg/ml. |
|
WB
Use a concentration of 1 mg/ml. Predicted molecular weight: 39 kDa. |
|
IHC-P
Use a concentration of 1 mg/ml. |
|
IHC-Fr
Use a concentration of 1 mg/ml. |
靶标
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功能
Receptor for the chemotactic and inflammatory peptide anaphylatoxin C5a. This receptor stimulates chemotaxis, granule enzyme release and superoxide anion production. -
序列相似性
Belongs to the G-protein coupled receptor 1 family. -
翻译后修饰
Sulfation plays a critical role in the association of the receptor with C5a, but no significant role in the ability of the receptor to transduce a signal and mobilize calcium in response to a small peptide agonist. -
细胞定位
Cell membrane. - Information by UniProt
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数据库链接
- Entrez Gene: 728 Human
- Omim: 113995 Human
- SwissProt: P21730 Human
- Unigene: 2161 Human
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别名
- ANAPHYLATOXIN RECEPTOR antibody
- C5a anaphylatoxin chemotactic receptor antibody
- C5a anaphylatoxin receptor antibody
see all
实验方案
数据表及文件
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SDS download
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Datasheet download
文献 (1)
ab24036 被引用在 1 文献中.
- Oppermann M et al. Probing the human receptor for C5a anaphylatoxin with site-directed antibodies. Identification of a potential ligand binding site on the NH2-terminal domain. J Immunol 151:3785-94 (1993). PubMed: 8376805