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AB17452

Anti-C2抗体[6E3]

Anti-C2 antibody [6E3]

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(1 Publication)

Mouse Monoclonal C2 antibody. Suitable for ELISA, WB and reacts with Human samples. Cited in 1 publication. Immunogen corresponding to Native Full Length Protein corresponding to Human C2.

查看别名

Complement C2, C3/C5 convertase, C2

关键信息

宿主种属

Mouse

克隆

Monoclonal

克隆号

6E3

亚型

IgG1

轻链类型

kappa

不含载体蛋白

No

反应种属

Human

应用

WB, ELISA

applications

免疫原

Native Full Length Protein corresponding to Human C2.

P06681

表位

Epitope specificity differs from that of ab17451 as determined by inhibition ELISA.

特异性

Strong reaction is seen with human serum/plasma and no reaction is seen with serum from patients deficient in C2. ab17452 reacts with C2 and a subfraction of C2 believed to be C2b.

反应性数据

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "ELISA" : {"fullname" : "ELISA", "shortname":"ELISA"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "ELISA-species-checked": "guaranteed", "ELISA-species-dilution-info": "", "ELISA-species-notes": "<p></p>", "WB-species-checked": "guaranteed", "WB-species-dilution-info": "", "WB-species-notes": "<p></p>" } } }

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性能和储存信息

形式
Liquid
纯化工艺
Affinity purification Protein G
存储溶液
pH: 7.4 Preservative: 0.097% Sodium azide Constituents: 2.9% Sodium chloride, 0.0268% PBS
运输条件
Blue Ice
推荐的短期储存条件
+4°C
推荐的长期储存条件
-20°C
分装信息
Upon delivery aliquot
储存信息
Avoid freeze / thaw cycle

产品实验方案

For this product, it's our understanding that no specific protocols are required. You can visit:

靶点信息

Component C2 which is part of the classical pathway of the complement system is cleaved by activated factor C1 into two fragments : C2b and C2a. C2a, a serine protease, then combines with complement factor C4b to generate the C3 or C5 convertase.
See full target information C2

文献 (1)

Recent publications for all applications. Explore the full list and refine your search

BMC immunology 11:43 PubMed20727163

2010

Recombinant human complement component C2 produced in a human cell line restores the classical complement pathway activity in-vitro: an alternative treatment for C2 deficiency diseases.

Applications

sELISA

Species

Human

Paolo G V Martini,Lynette C Cook,Scott Alderucci,Angela W Norton,Dianna M Lundberg,Susan M Fish,Knut Langsetmo,Göran Jönsson,Christian Lood,Birgitta Gullstrand,Kate J Zaleski,Nancy Savioli,Jason Lottherand,Charles Bedard,John Gill,Michael F Concino,Michael W Heartlein,Lennart Truedsson,Jan L Powell,Arthur O Tzianabos
View all publications

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