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AB81707

Anti-C1s抗体[M81]

Anti-C1s antibody [M81]

4

(1 Review)

|

(1 Publication)

Mouse Monoclonal C1S antibody. Suitable for IHC-P and reacts with Human samples. Cited in 1 publication.

查看别名

Complement C1s subcomponent, C1 esterase, Complement component 1 subcomponent s, C1S

1 Images
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-C1s antibody [M81] (AB81707)
  • IHC-P

Unknown

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-C1s antibody [M81] (AB81707)

ab81707, at a dilution of 1/50, staining paraffin embedded human liver melanoma cells by Immunohistochemistry. Insert is isotype control.

关键信息

宿主种属

Mouse

克隆

Monoclonal

克隆号

M81

亚型

IgG1

不含载体蛋白

No

反应种属

Human

应用

IHC-P

applications

表位

ab81707 reacts with an epitope on human C protein activated C1s, a subcomponent of the first component of C (C1). The epitope recognized by ab81707 is domain IV and/or V of the gamma domain of activated C1s.

特异性

ab81707 reacts around the binding site of C1s and reacts with both active and inactive C1s.

反应性数据

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "IHCP" : {"fullname" : "Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)", "shortname":"IHC-P"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "IHCP-species-checked": "testedAndGuaranteed", "IHCP-species-dilution-info": "", "IHCP-species-notes": "<p></p>" } } }

性能和储存信息

形式
Liquid
纯化说明
ab81707 is a purified, 0.2 µm filtered solution.
存储溶液
Constituents: PBS, 0.1% BSA
运输条件
Blue Ice
推荐的短期储存条件
+4°C
推荐的长期储存条件
-20°C
分装信息
Upon delivery aliquot
储存信息
Avoid freeze / thaw cycle

产品实验方案

For this product, it's our understanding that no specific protocols are required. You can visit:

靶点信息

C1s B chain is a serine protease that combines with C1q and C1r to form C1, the first component of the classical pathway of the complement system. C1r activates C1s so that it can, in turn, activate C2 and C4. Cleaves also IGFBP5 and thereby inhibits the trophic effects of IGF1.
See full target information C1S

文献 (1)

Recent publications for all applications. Explore the full list and refine your search

Journal of immunology (Baltimore, Md. : 1950) 142:2743-50 PubMed2522968

1989

Probing the C4-binding site on C1s with monoclonal antibodies. Evidence for a C4/C4b-binding site on the gamma-domain.

Applications

Unspecified application

Species

Unspecified reactive species

M Matsumoto,K Nagaki,H Kitamura,S Kuramitsu,S Nagasawa,T Seya
View all publications

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