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AB181179

重组Anti-C1orf163抗体[EPR13779-38]

Anti-C1orf163 antibody [EPR13779-38]

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(1 Publication)

Rabbit Recombinant Monoclonal C1orf163 antibody. Suitable for WB and reacts with Human samples. Cited in 1 publication.

查看别名

C1orf163, RESA1, SELRC1, COA7, Cytochrome c oxidase assembly factor 7, Beta-lactamase hcp-like protein, Respiratory chain assembly factor 1, Sel1 repeat-containing protein 1

1 Images
Western blot - Anti-C1orf163 antibody [EPR13779-38] (AB181179)
  • WB

Supplier Data

Western blot - Anti-C1orf163 antibody [EPR13779-38] (AB181179)

All lanes:

Western blot - Anti-C1orf163 antibody [EPR13779-38] (ab181179) at 1/5000 dilution

Lane 1:

Jurkat cell lysate at 20 µg

Lane 2:

HT-1376 cell lysate at 20 µg

Lane 3:

SH SY5Y cell lysate at 20 µg

Lane 4:

HepG2 cell lysate at 20 µg

Secondary

All lanes:

goat anti-rabbit IgG, (H+L), peroxidase conjugated at 1/1000 dilution

Predicted band size: 26 kDa

true

关键信息

宿主种属

Rabbit

克隆

Monoclonal

克隆号

EPR13779-38

亚型

IgG

不含载体蛋白

No

反应种属

Human

应用

WB

applications

免疫原

The exact immunogen used to generate this antibody is proprietary information.

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反应性数据

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "1/1000 - 1/5000", "WB-species-notes": "<p></p>" }, "Mouse": { "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "" }, "Rat": { "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "" } } }
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产品详情

Patented technology
Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb® patents.

What are the advantages of a recombinant monoclonal antibody?
This product is a recombinant monoclonal antibody, which offers several advantages including:

  • - High batch-to-batch consistency and reproducibility
  • - Improved sensitivity and specificity
  • - Long-term security of supply
  • - Animal-free batch production

For more information, read more on recombinant antibodies.

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性能和储存信息

形式
Liquid
纯度
Tissue culture supernatant
存储溶液
Preservative: 0.01% Sodium azide Constituents: PBS, 40% Glycerol (glycerin, glycerine), 0.05% BSA
运输条件
Blue Ice
推荐的短期储存时间
1-2 weeks
推荐的短期储存条件
+4°C
推荐的长期储存条件
-20°C
分装信息
Upon delivery aliquot
储存信息
Avoid freeze / thaw cycle
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补充信息

This supplementary information is collated from multiple sources and compiled automatically.

C1orf163 also known as Chromosome 1 Open Reading Frame 163 is a protein with a molecular mass of around 34 kDa. It localizes mainly in the mitochondria. The expression of C1orf163 has been observed in various tissues suggesting its presence in multiple physiological systems. However it shows higher expression specifically in heart and skeletal muscle tissues which indicates a potential muscle-related function.
Biological function summary

The protein C1orf163 seems to play a role in maintaining mitochondrial function. It is part of mitochondrial organization and possibly involved in energy metabolism due to its localization. Although not widely characterized C1orf163 is speculated to participate in the structural integrity of mitochondria. Researchers have identified it as a component of the mitochondrial complex suggesting its integration with other mitochondrial proteins that ensure mitochondrial health and function.

Pathways

C1orf163 appears associated with the mitochondrial electron transport chain (ETC). The electron transport chain is important for ATP production. C1orf163 interacts with components within the ETC pathway maintaining energy production processes. Its connection with other mitochondrial proteins like NADH:ubiquinone oxidoreductase (Complex I) supports energy conversion within cells.

Abnormalities in C1orf163 function or expression have links to disorders related to mitochondrial dysfunction. One such disorder is mitochondrial myopathy which affects muscle function. C1orf163 may interact with proteins such as COX10 further implicating it in mitochondrial-related pathologies. Studies aim to accurately determine its role in these conditions which could potentially identify therapeutic targets for mitochondrial disorders.
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产品实验方案

For this product, it's our understanding that no specific protocols are required. You can visit:
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靶点信息

Required for assembly of mitochondrial respiratory chain complex I and complex IV.
See full target information COA7
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文献 (1)

Recent publications for all applications. Explore the full list and refine your search

Medical science monitor : international medical journal of experimental and clinical research 24:3997-4008 PubMed29894468

2018

Role of Hydroxysteroid Dehydrogenase-Like 2 (HSDL2) in Human Ovarian Cancer.

Applications

Unspecified application

Species

Unspecified reactive species

Qing Sun,Yilin Zhang,Juanjuan Su,Tiechen Li,Yuxin Jiang
View all publications
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